Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | RNA_PROCESSING |
| Enrichment Score (ES) | -0.40966302 |
| Normalized Enrichment Score (NES) | -1.514716 |
| Nominal p-value | 0.014742015 |
| FDR q-value | 0.3153669 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 325 | 0.238 | 0.0224 | No |
| 2 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 389 | 0.213 | 0.0596 | No |
| 3 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 561 | 0.171 | 0.0803 | No |
| 4 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 977 | 0.123 | 0.0734 | No |
| 5 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1068 | 0.116 | 0.0895 | No |
| 6 | AGGF1 | AGGF1 Entrez, Source | angiogenic factor with G patch and FHA domains 1 | 1507 | 0.094 | 0.0749 | No |
| 7 | FARS2 | FARS2 Entrez, Source | phenylalanine-tRNA synthetase 2 (mitochondrial) | 1738 | 0.083 | 0.0739 | No |
| 8 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 1934 | 0.075 | 0.0740 | No |
| 9 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 2178 | 0.068 | 0.0691 | No |
| 10 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 2854 | 0.052 | 0.0284 | No |
| 11 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 3618 | 0.037 | -0.0219 | No |
| 12 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 3810 | 0.033 | -0.0298 | No |
| 13 | SLU7 | SLU7 Entrez, Source | - | 4976 | 0.016 | -0.1145 | No |
| 14 | TRNT1 | TRNT1 Entrez, Source | tRNA nucleotidyl transferase, CCA-adding, 1 | 5151 | 0.013 | -0.1250 | No |
| 15 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 5567 | 0.007 | -0.1548 | No |
| 16 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 5830 | 0.004 | -0.1738 | No |
| 17 | RBMS2 | RBMS2 Entrez, Source | RNA binding motif, single stranded interacting protein 2 | 6058 | 0.001 | -0.1906 | No |
| 18 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6461 | -0.004 | -0.2201 | No |
| 19 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 6720 | -0.007 | -0.2381 | No |
| 20 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 7120 | -0.012 | -0.2658 | No |
| 21 | SF3A2 | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 7150 | -0.012 | -0.2655 | No |
| 22 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 7205 | -0.013 | -0.2670 | No |
| 23 | INTS6 | INTS6 Entrez, Source | integrator complex subunit 6 | 7424 | -0.016 | -0.2803 | No |
| 24 | GRSF1 | GRSF1 Entrez, Source | G-rich RNA sequence binding factor 1 | 7484 | -0.016 | -0.2815 | No |
| 25 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 7584 | -0.018 | -0.2855 | No |
| 26 | POP4 | POP4 Entrez, Source | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) | 7679 | -0.019 | -0.2888 | No |
| 27 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 7775 | -0.020 | -0.2919 | No |
| 28 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 7790 | -0.021 | -0.2889 | No |
| 29 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8111 | -0.025 | -0.3081 | No |
| 30 | DUSP11 | DUSP11 Entrez, Source | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 8581 | -0.032 | -0.3371 | No |
| 31 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 8696 | -0.034 | -0.3391 | No |
| 32 | CPSF3 | CPSF3 Entrez, Source | cleavage and polyadenylation specific factor 3, 73kDa | 8954 | -0.037 | -0.3512 | No |
| 33 | DHX8 | DHX8 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 9187 | -0.040 | -0.3608 | No |
| 34 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 9386 | -0.043 | -0.3672 | No |
| 35 | RBM5 | RBM5 Entrez, Source | RNA binding motif protein 5 | 9487 | -0.045 | -0.3659 | No |
| 36 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 10069 | -0.055 | -0.3989 | Yes |
| 37 | GEMIN6 | GEMIN6 Entrez, Source | gem (nuclear organelle) associated protein 6 | 10170 | -0.056 | -0.3954 | Yes |
| 38 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 10205 | -0.057 | -0.3867 | Yes |
| 39 | DHX16 | DHX16 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 10268 | -0.058 | -0.3800 | Yes |
| 40 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 10434 | -0.061 | -0.3804 | Yes |
| 41 | CRNKL1 | CRNKL1 Entrez, Source | Crn, crooked neck-like 1 (Drosophila) | 10445 | -0.061 | -0.3692 | Yes |
| 42 | FBL | FBL Entrez, Source | fibrillarin | 10535 | -0.063 | -0.3635 | Yes |
| 43 | PRPF8 | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 10586 | -0.064 | -0.3547 | Yes |
| 44 | PPAN | PPAN Entrez, Source | peter pan homolog (Drosophila) | 10647 | -0.065 | -0.3463 | Yes |
| 45 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10688 | -0.066 | -0.3364 | Yes |
| 46 | CDC2L1 | CDC2L1 Entrez, Source | cell division cycle 2-like 1 (PITSLRE proteins) | 10741 | -0.067 | -0.3271 | Yes |
| 47 | PPIG | PPIG Entrez, Source | peptidylprolyl isomerase G (cyclophilin G) | 10743 | -0.067 | -0.3139 | Yes |
| 48 | SNRPN | SNRPN Entrez, Source | small nuclear ribonucleoprotein polypeptide N | 10762 | -0.067 | -0.3020 | Yes |
| 49 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 10794 | -0.068 | -0.2909 | Yes |
| 50 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 10861 | -0.070 | -0.2821 | Yes |
| 51 | SRPK1 | SRPK1 Entrez, Source | SFRS protein kinase 1 | 10895 | -0.071 | -0.2707 | Yes |
| 52 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 10990 | -0.073 | -0.2634 | Yes |
| 53 | SSB | SSB Entrez, Source | Sjogren syndrome antigen B (autoantigen La) | 10994 | -0.073 | -0.2492 | Yes |
| 54 | NUFIP1 | NUFIP1 Entrez, Source | nuclear fragile X mental retardation protein interacting protein 1 | 11003 | -0.073 | -0.2353 | Yes |
| 55 | DDX20 | DDX20 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 11083 | -0.075 | -0.2265 | Yes |
| 56 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 11170 | -0.077 | -0.2177 | Yes |
| 57 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 11203 | -0.078 | -0.2047 | Yes |
| 58 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11343 | -0.083 | -0.1989 | Yes |
| 59 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 11513 | -0.087 | -0.1946 | Yes |
| 60 | DDX39 | DDX39 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 | 11591 | -0.089 | -0.1829 | Yes |
| 61 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 11660 | -0.090 | -0.1702 | Yes |
| 62 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 11763 | -0.094 | -0.1593 | Yes |
| 63 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 11792 | -0.095 | -0.1427 | Yes |
| 64 | NOL5A | NOL5A Entrez, Source | nucleolar protein 5A (56kDa with KKE/D repeat) | 11821 | -0.096 | -0.1259 | Yes |
| 65 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 11902 | -0.099 | -0.1123 | Yes |
| 66 | CSTF1 | CSTF1 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 11951 | -0.101 | -0.0961 | Yes |
| 67 | HNRPF | HNRPF Entrez, Source | heterogeneous nuclear ribonucleoprotein F | 11999 | -0.103 | -0.0794 | Yes |
| 68 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12122 | -0.108 | -0.0672 | Yes |
| 69 | PABPC4 | PABPC4 Entrez, Source | poly(A) binding protein, cytoplasmic 4 (inducible form) | 12431 | -0.123 | -0.0663 | Yes |
| 70 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12447 | -0.123 | -0.0431 | Yes |
| 71 | RBM3 | RBM3 Entrez, Source | RNA binding motif (RNP1, RRM) protein 3 | 12503 | -0.128 | -0.0220 | Yes |
| 72 | ASCC3L1 | ASCC3L1 Entrez, Source | activating signal cointegrator 1 complex subunit 3-like 1 | 12985 | -0.180 | -0.0227 | Yes |
| 73 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 13196 | -0.252 | 0.0110 | Yes |
