Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | RNA_SPLICING |
| Enrichment Score (ES) | -0.45528567 |
| Normalized Enrichment Score (NES) | -1.4991945 |
| Nominal p-value | 0.024017468 |
| FDR q-value | 0.32922822 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 325 | 0.238 | 0.0604 | No |
| 2 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 977 | 0.123 | 0.0554 | No |
| 3 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1068 | 0.116 | 0.0901 | No |
| 4 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 2178 | 0.068 | 0.0309 | No |
| 5 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 2854 | 0.052 | -0.0015 | No |
| 6 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 3618 | 0.037 | -0.0458 | No |
| 7 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 3810 | 0.033 | -0.0483 | No |
| 8 | SLU7 | SLU7 Entrez, Source | - | 4976 | 0.016 | -0.1303 | No |
| 9 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 5567 | 0.007 | -0.1720 | No |
| 10 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6461 | -0.004 | -0.2378 | No |
| 11 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 6720 | -0.007 | -0.2545 | No |
| 12 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 7120 | -0.012 | -0.2802 | No |
| 13 | SF3A2 | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 7150 | -0.012 | -0.2780 | No |
| 14 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 7205 | -0.013 | -0.2773 | No |
| 15 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 7584 | -0.018 | -0.2994 | No |
| 16 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 7790 | -0.021 | -0.3075 | No |
| 17 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8111 | -0.025 | -0.3226 | No |
| 18 | DHX8 | DHX8 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 9187 | -0.040 | -0.3891 | No |
| 19 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 10069 | -0.055 | -0.4358 | Yes |
| 20 | GEMIN6 | GEMIN6 Entrez, Source | gem (nuclear organelle) associated protein 6 | 10170 | -0.056 | -0.4233 | Yes |
| 21 | DHX16 | DHX16 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 10268 | -0.058 | -0.4099 | Yes |
| 22 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 10434 | -0.061 | -0.4006 | Yes |
| 23 | CRNKL1 | CRNKL1 Entrez, Source | Crn, crooked neck-like 1 (Drosophila) | 10445 | -0.061 | -0.3796 | Yes |
| 24 | PRPF8 | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 10586 | -0.064 | -0.3674 | Yes |
| 25 | PPAN | PPAN Entrez, Source | peter pan homolog (Drosophila) | 10647 | -0.065 | -0.3487 | Yes |
| 26 | PPIG | PPIG Entrez, Source | peptidylprolyl isomerase G (cyclophilin G) | 10743 | -0.067 | -0.3319 | Yes |
| 27 | SNRPN | SNRPN Entrez, Source | small nuclear ribonucleoprotein polypeptide N | 10762 | -0.067 | -0.3092 | Yes |
| 28 | SRPK1 | SRPK1 Entrez, Source | SFRS protein kinase 1 | 10895 | -0.071 | -0.2940 | Yes |
| 29 | DDX20 | DDX20 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 11083 | -0.075 | -0.2812 | Yes |
| 30 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 11170 | -0.077 | -0.2601 | Yes |
| 31 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11343 | -0.083 | -0.2436 | Yes |
| 32 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 11513 | -0.087 | -0.2254 | Yes |
| 33 | DDX39 | DDX39 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 | 11591 | -0.089 | -0.1996 | Yes |
| 34 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 11660 | -0.090 | -0.1725 | Yes |
| 35 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 11792 | -0.095 | -0.1484 | Yes |
| 36 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 11902 | -0.099 | -0.1212 | Yes |
| 37 | HNRPF | HNRPF Entrez, Source | heterogeneous nuclear ribonucleoprotein F | 11999 | -0.103 | -0.0917 | Yes |
| 38 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12122 | -0.108 | -0.0623 | Yes |
| 39 | ASCC3L1 | ASCC3L1 Entrez, Source | activating signal cointegrator 1 complex subunit 3-like 1 | 12985 | -0.180 | -0.0629 | Yes |
| 40 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 13196 | -0.252 | 0.0110 | Yes |
