Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | STATIN_PATHWAY_PHARMGKB |
| Enrichment Score (ES) | 0.71685606 |
| Normalized Enrichment Score (NES) | 1.790022 |
| Nominal p-value | 0.0037383179 |
| FDR q-value | 0.03341342 |
| FWER p-Value | 0.976 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LPL | LPL Entrez, Source | lipoprotein lipase | 24 | 0.680 | 0.1974 | Yes |
| 2 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 57 | 0.561 | 0.3593 | Yes |
| 3 | LIPC | LIPC Entrez, Source | lipase, hepatic | 92 | 0.451 | 0.4887 | Yes |
| 4 | APOC1 | APOC1 Entrez, Source | apolipoprotein C-I | 102 | 0.426 | 0.6129 | Yes |
| 5 | APOA4 | APOA4 Entrez, Source | apolipoprotein A-IV | 255 | 0.280 | 0.6834 | Yes |
| 6 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 562 | 0.171 | 0.7105 | Yes |
| 7 | CYP7A1 | CYP7A1 Entrez, Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 963 | 0.124 | 0.7169 | Yes |
| 8 | APOE | APOE Entrez, Source | apolipoprotein E | 2345 | 0.063 | 0.6318 | No |
| 9 | APOA1 | APOA1 Entrez, Source | apolipoprotein A-I | 2953 | 0.050 | 0.6008 | No |
| 10 | DGAT1 | DGAT1 Entrez, Source | diacylglycerol O-acyltransferase homolog 1 (mouse) | 3479 | 0.039 | 0.5728 | No |
| 11 | APOC3 | APOC3 Entrez, Source | apolipoprotein C-III | 5734 | 0.005 | 0.4053 | No |
| 12 | LDLR | LDLR Entrez, Source | low density lipoprotein receptor (familial hypercholesterolemia) | 6572 | -0.005 | 0.3441 | No |
| 13 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 10559 | -0.063 | 0.0635 | No |
| 14 | LCAT | LCAT Entrez, Source | lecithin-cholesterol acyltransferase | 11800 | -0.096 | -0.0015 | No |
| 15 | HMGCR | HMGCR Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 11844 | -0.097 | 0.0238 | No |
| 16 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 13254 | -0.302 | 0.0066 | No |
