Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TAKEDA_NUP8_HOXA9_10D_DN |
| Enrichment Score (ES) | 0.61082983 |
| Normalized Enrichment Score (NES) | 2.1060784 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0019153232 |
| FWER p-Value | 0.028 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CD24 | CD24 Entrez, Source | CD24 molecule | 17 | 0.726 | 0.0640 | Yes |
| 2 | PDK4 | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 22 | 0.685 | 0.1252 | Yes |
| 3 | DAB2 | DAB2 Entrez, Source | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 31 | 0.661 | 0.1841 | Yes |
| 4 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 44 | 0.606 | 0.2377 | Yes |
| 5 | IL1R2 | IL1R2 Entrez, Source | interleukin 1 receptor, type II | 46 | 0.599 | 0.2915 | Yes |
| 6 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 73 | 0.484 | 0.3330 | Yes |
| 7 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 118 | 0.402 | 0.3658 | Yes |
| 8 | HS3ST2 | HS3ST2 Entrez, Source | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 129 | 0.391 | 0.4002 | Yes |
| 9 | F13A1 | F13A1 Entrez, Source | coagulation factor XIII, A1 polypeptide | 135 | 0.379 | 0.4339 | Yes |
| 10 | RASSF4 | RASSF4 Entrez, Source | Ras association (RalGDS/AF-6) domain family 4 | 146 | 0.366 | 0.4661 | Yes |
| 11 | TSPAN2 | TSPAN2 Entrez, Source | tetraspanin 2 | 168 | 0.349 | 0.4958 | Yes |
| 12 | RNASE1 | RNASE1 Entrez, Source | ribonuclease, RNase A family, 1 (pancreatic) | 175 | 0.341 | 0.5260 | Yes |
| 13 | ST14 | ST14 Entrez, Source | suppression of tumorigenicity 14 (colon carcinoma) | 220 | 0.306 | 0.5502 | Yes |
| 14 | CD9 | CD9 Entrez, Source | CD9 molecule | 299 | 0.250 | 0.5668 | Yes |
| 15 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 330 | 0.237 | 0.5859 | Yes |
| 16 | FABP3 | FABP3 Entrez, Source | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 666 | 0.155 | 0.5746 | Yes |
| 17 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 710 | 0.149 | 0.5848 | Yes |
| 18 | HS3ST1 | HS3ST1 Entrez, Source | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 830 | 0.136 | 0.5880 | Yes |
| 19 | FCER1A | FCER1A Entrez, Source | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 844 | 0.135 | 0.5992 | Yes |
| 20 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 1062 | 0.117 | 0.5933 | Yes |
| 21 | CCL7 | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 1159 | 0.111 | 0.5961 | Yes |
| 22 | TMEM45B | TMEM45B Entrez, Source | transmembrane protein 45B | 1246 | 0.108 | 0.5993 | Yes |
| 23 | SLC38A6 | SLC38A6 Entrez, Source | solute carrier family 38, member 6 | 1356 | 0.101 | 0.6001 | Yes |
| 24 | HEXA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 1360 | 0.101 | 0.6089 | Yes |
| 25 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 1541 | 0.092 | 0.6036 | Yes |
| 26 | MS4A2 | MS4A2 Entrez, Source | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | 1555 | 0.091 | 0.6108 | Yes |
| 27 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 1832 | 0.079 | 0.5971 | No |
| 28 | ACSL6 | ACSL6 Entrez, Source | acyl-CoA synthetase long-chain family member 6 | 1985 | 0.074 | 0.5923 | No |
| 29 | LGMN | LGMN Entrez, Source | legumain | 2054 | 0.071 | 0.5935 | No |
| 30 | PDE4DIP | PDE4DIP Entrez, Source | phosphodiesterase 4D interacting protein (myomegalin) | 2158 | 0.068 | 0.5919 | No |
| 31 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 2181 | 0.068 | 0.5963 | No |
| 32 | PADI4 | PADI4 Entrez, Source | peptidyl arginine deiminase, type IV | 2199 | 0.067 | 0.6011 | No |
| 33 | TACSTD2 | TACSTD2 Entrez, Source | tumor-associated calcium signal transducer 2 | 2200 | 0.067 | 0.6071 | No |
| 34 | APOE | APOE Entrez, Source | apolipoprotein E | 2345 | 0.063 | 0.6020 | No |
| 35 | SLC25A27 | SLC25A27 Entrez, Source | solute carrier family 25, member 27 | 2374 | 0.063 | 0.6055 | No |
| 36 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 3267 | 0.043 | 0.5421 | No |
| 37 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 3304 | 0.042 | 0.5432 | No |
| 38 | RTN1 | RTN1 Entrez, Source | reticulon 1 | 3317 | 0.042 | 0.5461 | No |
| 39 | HRH4 | HRH4 Entrez, Source | histamine receptor H4 | 3333 | 0.042 | 0.5487 | No |
| 40 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 3468 | 0.039 | 0.5421 | No |
| 41 | RGC32 | RGC32 Entrez, Source | - | 3775 | 0.034 | 0.5221 | No |
| 42 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 3833 | 0.033 | 0.5208 | No |
| 43 | C1QA | C1QA Entrez, Source | complement component 1, q subcomponent, A chain | 4037 | 0.030 | 0.5081 | No |
| 44 | SLC7A8 | SLC7A8 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 | 4160 | 0.028 | 0.5014 | No |
| 45 | KCNJ15 | KCNJ15 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 15 | 4287 | 0.026 | 0.4942 | No |
| 46 | BLNK | BLNK Entrez, Source | B-cell linker | 4539 | 0.022 | 0.4772 | No |
| 47 | RPS6KA2 | RPS6KA2 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 4610 | 0.021 | 0.4738 | No |
| 48 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 4666 | 0.020 | 0.4715 | No |
| 49 | GPD2 | GPD2 Entrez, Source | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 4761 | 0.019 | 0.4661 | No |
| 50 | MAPK13 | MAPK13 Entrez, Source | mitogen-activated protein kinase 13 | 5354 | 0.010 | 0.4224 | No |
| 51 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 5434 | 0.009 | 0.4173 | No |
| 52 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 5592 | 0.007 | 0.4061 | No |
| 53 | PPBP | PPBP Entrez, Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 5643 | 0.006 | 0.4029 | No |
| 54 | GGTA1 | GGTA1 Entrez, Source | glycoprotein, alpha-galactosyltransferase 1 | 5771 | 0.005 | 0.3937 | No |
| 55 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 5939 | 0.003 | 0.3814 | No |
| 56 | C1QC | C1QC Entrez, Source | complement component 1, q subcomponent, C chain | 6016 | 0.002 | 0.3758 | No |
| 57 | ACE | ACE Entrez, Source | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 6152 | -0.000 | 0.3656 | No |
| 58 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 6410 | -0.003 | 0.3466 | No |
| 59 | SRPX | SRPX Entrez, Source | sushi-repeat-containing protein, X-linked | 6552 | -0.005 | 0.3364 | No |
| 60 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 6950 | -0.010 | 0.3074 | No |
| 61 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 7060 | -0.011 | 0.3002 | No |
| 62 | OLIG1 | OLIG1 Entrez, Source | oligodendrocyte transcription factor 1 | 7100 | -0.012 | 0.2983 | No |
| 63 | RAP1A | RAP1A Entrez, Source | RAP1A, member of RAS oncogene family | 7119 | -0.012 | 0.2980 | No |
| 64 | CORO2A | CORO2A Entrez, Source | coronin, actin binding protein, 2A | 7394 | -0.015 | 0.2787 | No |
| 65 | S100B | S100B Entrez, Source | S100 calcium binding protein B | 8430 | -0.030 | 0.2033 | No |
| 66 | PPP1R1B | PPP1R1B Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32) | 8670 | -0.033 | 0.1883 | No |
| 67 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 8926 | -0.036 | 0.1724 | No |
| 68 | C5AR1 | C5AR1 Entrez, Source | complement component 5a receptor 1 | 9594 | -0.047 | 0.1263 | No |
| 69 | CHI3L1 | CHI3L1 Entrez, Source | chitinase 3-like 1 (cartilage glycoprotein-39) | 9869 | -0.051 | 0.1102 | No |
| 70 | PPP2R2B | PPP2R2B Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform | 10110 | -0.055 | 0.0971 | No |
| 71 | CTSB | CTSB Entrez, Source | cathepsin B | 10352 | -0.059 | 0.0842 | No |
| 72 | CEBPE | CEBPE Entrez, Source | CCAAT/enhancer binding protein (C/EBP), epsilon | 10710 | -0.066 | 0.0633 | No |
| 73 | C1QB | C1QB Entrez, Source | complement component 1, q subcomponent, B chain | 10939 | -0.072 | 0.0525 | No |
| 74 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 11324 | -0.082 | 0.0310 | No |
| 75 | A2M | A2M Entrez, Source | alpha-2-macroglobulin | 11335 | -0.082 | 0.0376 | No |
| 76 | PCSK5 | PCSK5 Entrez, Source | proprotein convertase subtilisin/kexin type 5 | 11336 | -0.082 | 0.0450 | No |
| 77 | ACP5 | ACP5 Entrez, Source | acid phosphatase 5, tartrate resistant | 11379 | -0.083 | 0.0494 | No |
| 78 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 12406 | -0.122 | -0.0171 | No |
| 79 | PTGER3 | PTGER3 Entrez, Source | prostaglandin E receptor 3 (subtype EP3) | 12492 | -0.127 | -0.0121 | No |
| 80 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 12642 | -0.137 | -0.0110 | No |
| 81 | RASGRP1 | RASGRP1 Entrez, Source | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 12782 | -0.150 | -0.0080 | No |
| 82 | SLCO2B1 | SLCO2B1 Entrez, Source | solute carrier organic anion transporter family, member 2B1 | 13208 | -0.258 | -0.0168 | No |
| 83 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 13250 | -0.299 | 0.0069 | No |
