Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TGFBETA_EARLY_UP |
| Enrichment Score (ES) | 0.6790307 |
| Normalized Enrichment Score (NES) | 2.0821033 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0027499537 |
| FWER p-Value | 0.053 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 3 | 1.046 | 0.1728 | Yes |
| 2 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 12 | 0.803 | 0.3050 | Yes |
| 3 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 15 | 0.737 | 0.4269 | Yes |
| 4 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 122 | 0.399 | 0.4850 | Yes |
| 5 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 200 | 0.321 | 0.5323 | Yes |
| 6 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 234 | 0.297 | 0.5789 | Yes |
| 7 | RND3 | RND3 Entrez, Source | Rho family GTPase 3 | 350 | 0.230 | 0.6083 | Yes |
| 8 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 567 | 0.170 | 0.6203 | Yes |
| 9 | PXN | PXN Entrez, Source | paxillin | 617 | 0.163 | 0.6435 | Yes |
| 10 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 710 | 0.149 | 0.6613 | Yes |
| 11 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 785 | 0.141 | 0.6790 | Yes |
| 12 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 1312 | 0.104 | 0.6566 | No |
| 13 | CDH6 | CDH6 Entrez, Source | cadherin 6, type 2, K-cadherin (fetal kidney) | 1405 | 0.098 | 0.6659 | No |
| 14 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 1975 | 0.074 | 0.6354 | No |
| 15 | FN1 | FN1 Entrez, Source | fibronectin 1 | 2637 | 0.057 | 0.5950 | No |
| 16 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2713 | 0.055 | 0.5985 | No |
| 17 | RHOG | RHOG Entrez, Source | ras homolog gene family, member G (rho G) | 2819 | 0.052 | 0.5992 | No |
| 18 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 3143 | 0.046 | 0.5825 | No |
| 19 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 3147 | 0.045 | 0.5898 | No |
| 20 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 3256 | 0.044 | 0.5889 | No |
| 21 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 3714 | 0.035 | 0.5603 | No |
| 22 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 3764 | 0.034 | 0.5623 | No |
| 23 | WNT2B | WNT2B Entrez, Source | wingless-type MMTV integration site family, member 2B | 3814 | 0.033 | 0.5641 | No |
| 24 | BSG | BSG Entrez, Source | basigin (Ok blood group) | 3928 | 0.031 | 0.5608 | No |
| 25 | NID1 | NID1 Entrez, Source | nidogen 1 | 6133 | 0.000 | 0.3952 | No |
| 26 | ITGB2 | ITGB2 Entrez, Source | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 6196 | -0.001 | 0.3906 | No |
| 27 | LRRC17 | LRRC17 Entrez, Source | leucine rich repeat containing 17 | 6786 | -0.008 | 0.3476 | No |
| 28 | ZYX | ZYX Entrez, Source | zyxin | 7461 | -0.016 | 0.2997 | No |
| 29 | ARHGDIA | ARHGDIA Entrez, Source | Rho GDP dissociation inhibitor (GDI) alpha | 9058 | -0.038 | 0.1860 | No |
| 30 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 9179 | -0.040 | 0.1836 | No |
| 31 | DVL1 | DVL1 Entrez, Source | dishevelled, dsh homolog 1 (Drosophila) | 9309 | -0.042 | 0.1809 | No |
| 32 | JUP | JUP Entrez, Source | junction plakoglobin | 10241 | -0.057 | 0.1204 | No |
| 33 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 10417 | -0.061 | 0.1172 | No |
| 34 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 10559 | -0.063 | 0.1171 | No |
| 35 | RHOQ | RHOQ Entrez, Source | ras homolog gene family, member Q | 11086 | -0.075 | 0.0901 | No |
| 36 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 11121 | -0.076 | 0.1001 | No |
| 37 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 12996 | -0.183 | -0.0104 | No |
| 38 | NOTCH2 | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 13133 | -0.220 | 0.0157 | No |
