Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TISSUE_DEVELOPMENT |
| Enrichment Score (ES) | 0.6058668 |
| Normalized Enrichment Score (NES) | 2.034119 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0036717497 |
| FWER p-Value | 0.112 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 14 | 0.770 | 0.0898 | Yes |
| 2 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 28 | 0.668 | 0.1675 | Yes |
| 3 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 32 | 0.660 | 0.2451 | Yes |
| 4 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 44 | 0.606 | 0.3157 | Yes |
| 5 | MGP | MGP Entrez, Source | matrix Gla protein | 62 | 0.533 | 0.3772 | Yes |
| 6 | FST | FST Entrez, Source | follistatin | 132 | 0.388 | 0.4178 | Yes |
| 7 | LAMC1 | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 224 | 0.303 | 0.4466 | Yes |
| 8 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 234 | 0.297 | 0.4809 | Yes |
| 9 | GJB5 | GJB5 Entrez, Source | gap junction protein, beta 5 (connexin 31.1) | 322 | 0.239 | 0.5026 | Yes |
| 10 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 367 | 0.223 | 0.5255 | Yes |
| 11 | STS | STS Entrez, Source | steroid sulfatase (microsomal), arylsulfatase C, isozyme S | 436 | 0.199 | 0.5438 | Yes |
| 12 | BTD | BTD Entrez, Source | biotinidase | 670 | 0.155 | 0.5446 | Yes |
| 13 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 738 | 0.146 | 0.5567 | Yes |
| 14 | IL17F | IL17F Entrez, Source | interleukin 17F | 946 | 0.125 | 0.5559 | Yes |
| 15 | KL | KL Entrez, Source | klotho | 967 | 0.124 | 0.5690 | Yes |
| 16 | DSPP | DSPP Entrez, Source | dentin sialophosphoprotein | 1020 | 0.120 | 0.5792 | Yes |
| 17 | PLOD1 | PLOD1 Entrez, Source | procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 | 1057 | 0.117 | 0.5903 | Yes |
| 18 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 1086 | 0.116 | 0.6019 | Yes |
| 19 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 1344 | 0.102 | 0.5945 | Yes |
| 20 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 1352 | 0.101 | 0.6059 | Yes |
| 21 | TIE1 | TIE1 Entrez, Source | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 1674 | 0.086 | 0.5918 | No |
| 22 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1840 | 0.078 | 0.5886 | No |
| 23 | GHSR | GHSR Entrez, Source | growth hormone secretagogue receptor | 1979 | 0.074 | 0.5869 | No |
| 24 | PTF1A | PTF1A Entrez, Source | pancreas specific transcription factor, 1a | 2008 | 0.073 | 0.5934 | No |
| 25 | OSTF1 | OSTF1 Entrez, Source | osteoclast stimulating factor 1 | 2399 | 0.062 | 0.5713 | No |
| 26 | DMP1 | DMP1 Entrez, Source | dentin matrix acidic phosphoprotein | 2433 | 0.061 | 0.5761 | No |
| 27 | COL11A1 | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 2472 | 0.060 | 0.5803 | No |
| 28 | CRABP2 | CRABP2 Entrez, Source | cellular retinoic acid binding protein 2 | 2566 | 0.058 | 0.5802 | No |
| 29 | SLIT2 | SLIT2 Entrez, Source | slit homolog 2 (Drosophila) | 2885 | 0.051 | 0.5623 | No |
| 30 | TWIST2 | TWIST2 Entrez, Source | twist homolog 2 (Drosophila) | 3829 | 0.033 | 0.4951 | No |
| 31 | ATP2C1 | ATP2C1 Entrez, Source | ATPase, Ca++ transporting, type 2C, member 1 | 3896 | 0.032 | 0.4939 | No |
| 32 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 3943 | 0.031 | 0.4941 | No |
| 33 | GDF11 | GDF11 Entrez, Source | growth differentiation factor 11 | 4049 | 0.030 | 0.4897 | No |
| 34 | MATK | MATK Entrez, Source | megakaryocyte-associated tyrosine kinase | 4259 | 0.026 | 0.4770 | No |
| 35 | VAX2 | VAX2 Entrez, Source | ventral anterior homeobox 2 | 4278 | 0.026 | 0.4787 | No |
| 36 | CASR | CASR Entrez, Source | calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism) | 4461 | 0.023 | 0.4676 | No |
| 37 | PTHLH | PTHLH Entrez, Source | parathyroid hormone-like hormone | 4594 | 0.021 | 0.4602 | No |
| 38 | AHSG | AHSG Entrez, Source | alpha-2-HS-glycoprotein | 4733 | 0.019 | 0.4521 | No |
| 39 | FLOT2 | FLOT2 Entrez, Source | flotillin 2 | 4869 | 0.017 | 0.4439 | No |
| 40 | GHRL | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 5231 | 0.012 | 0.4182 | No |
| 41 | ERCC3 | ERCC3 Entrez, Source | excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) | 5284 | 0.011 | 0.4156 | No |
| 42 | EYA2 | EYA2 Entrez, Source | eyes absent homolog 2 (Drosophila) | 5381 | 0.010 | 0.4095 | No |
| 43 | DSP | DSP Entrez, Source | desmoplakin | 5452 | 0.009 | 0.4053 | No |
| 44 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 5875 | 0.004 | 0.3739 | No |
| 45 | BMP1 | BMP1 Entrez, Source | bone morphogenetic protein 1 | 5892 | 0.004 | 0.3732 | No |
| 46 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 6323 | -0.002 | 0.3410 | No |
| 47 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 6404 | -0.003 | 0.3354 | No |
| 48 | GLI1 | GLI1 Entrez, Source | glioma-associated oncogene homolog 1 (zinc finger protein) | 6483 | -0.004 | 0.3300 | No |
| 49 | RUNX2 | RUNX2 Entrez, Source | runt-related transcription factor 2 | 6625 | -0.006 | 0.3201 | No |
| 50 | TCF21 | TCF21 Entrez, Source | transcription factor 21 | 6846 | -0.009 | 0.3045 | No |
| 51 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 7435 | -0.016 | 0.2621 | No |
| 52 | KLK8 | KLK8 Entrez, Source | kallikrein 8 (neuropsin/ovasin) | 7500 | -0.017 | 0.2593 | No |
| 53 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 8226 | -0.027 | 0.2078 | No |
| 54 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 8847 | -0.035 | 0.1653 | No |
| 55 | STX2 | STX2 Entrez, Source | syntaxin 2 | 8992 | -0.037 | 0.1588 | No |
| 56 | NME2 | NME2 Entrez, Source | non-metastatic cells 2, protein (NM23B) expressed in | 9131 | -0.039 | 0.1531 | No |
| 57 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 9565 | -0.046 | 0.1259 | No |
| 58 | ACVR1 | ACVR1 Entrez, Source | activin A receptor, type I | 9665 | -0.048 | 0.1241 | No |
| 59 | ATP2A2 | ATP2A2 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 9899 | -0.052 | 0.1127 | No |
| 60 | POU2F3 | POU2F3 Entrez, Source | POU domain, class 2, transcription factor 3 | 10351 | -0.059 | 0.0857 | No |
| 61 | RBP2 | RBP2 Entrez, Source | retinol binding protein 2, cellular | 10395 | -0.060 | 0.0895 | No |
| 62 | HCK | HCK Entrez, Source | hemopoietic cell kinase | 12385 | -0.120 | -0.0461 | No |
| 63 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 12520 | -0.130 | -0.0409 | No |
| 64 | DHCR24 | DHCR24 Entrez, Source | 24-dehydrocholesterol reductase | 12656 | -0.138 | -0.0349 | No |
| 65 | SECTM1 | SECTM1 Entrez, Source | secreted and transmembrane 1 | 12728 | -0.144 | -0.0232 | No |
| 66 | KLK7 | KLK7 Entrez, Source | kallikrein 7 (chymotryptic, stratum corneum) | 12860 | -0.160 | -0.0143 | No |
| 67 | FABP5 | FABP5 Entrez, Source | fatty acid binding protein 5 (psoriasis-associated) | 12975 | -0.177 | -0.0020 | No |
| 68 | JAK2 | JAK2 Entrez, Source | Janus kinase 2 (a protein tyrosine kinase) | 13193 | -0.251 | 0.0112 | No |
