Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TPA_SENS_EARLY_UP |
| Enrichment Score (ES) | 0.6336533 |
| Normalized Enrichment Score (NES) | 1.87537 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.01962286 |
| FWER p-Value | 0.752 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HMGCS2 | HMGCS2 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) | 66 | 0.519 | 0.1220 | Yes |
| 2 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 69 | 0.494 | 0.2426 | Yes |
| 3 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 183 | 0.333 | 0.3157 | Yes |
| 4 | CYBA | CYBA Entrez, Source | cytochrome b-245, alpha polypeptide | 353 | 0.229 | 0.3590 | Yes |
| 5 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 367 | 0.223 | 0.4126 | Yes |
| 6 | ADORA2B | ADORA2B Entrez, Source | adenosine A2b receptor | 482 | 0.186 | 0.4494 | Yes |
| 7 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 577 | 0.168 | 0.4834 | Yes |
| 8 | HBEGF | HBEGF Entrez, Source | heparin-binding EGF-like growth factor | 717 | 0.149 | 0.5094 | Yes |
| 9 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 888 | 0.130 | 0.5285 | Yes |
| 10 | GABRG2 | GABRG2 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 962 | 0.124 | 0.5534 | Yes |
| 11 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 1086 | 0.116 | 0.5725 | Yes |
| 12 | CCL7 | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 1159 | 0.111 | 0.5943 | Yes |
| 13 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 1208 | 0.109 | 0.6174 | Yes |
| 14 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 1327 | 0.103 | 0.6337 | Yes |
| 15 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 1828 | 0.079 | 0.6154 | No |
| 16 | TNFRSF8 | TNFRSF8 Entrez, Source | tumor necrosis factor receptor superfamily, member 8 | 3295 | 0.043 | 0.5157 | No |
| 17 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 4101 | 0.029 | 0.4622 | No |
| 18 | CCNF | CCNF Entrez, Source | cyclin F | 4470 | 0.023 | 0.4401 | No |
| 19 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 4899 | 0.017 | 0.4121 | No |
| 20 | AKAP7 | AKAP7 Entrez, Source | A kinase (PRKA) anchor protein 7 | 5273 | 0.011 | 0.3869 | No |
| 21 | AGER | AGER Entrez, Source | advanced glycosylation end product-specific receptor | 5780 | 0.005 | 0.3500 | No |
| 22 | DAG1 | DAG1 Entrez, Source | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 6712 | -0.007 | 0.2818 | No |
| 23 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 6928 | -0.010 | 0.2680 | No |
| 24 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 7790 | -0.021 | 0.2084 | No |
| 25 | SMARCB1 | SMARCB1 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 7987 | -0.023 | 0.1994 | No |
| 26 | RAB2 | RAB2 Entrez, Source | RAB2, member RAS oncogene family | 9314 | -0.042 | 0.1100 | No |
| 27 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 9367 | -0.043 | 0.1166 | No |
| 28 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 9474 | -0.045 | 0.1195 | No |
| 29 | CCT5 | CCT5 Entrez, Source | chaperonin containing TCP1, subunit 5 (epsilon) | 9486 | -0.045 | 0.1297 | No |
| 30 | MEOX2 | MEOX2 Entrez, Source | mesenchyme homeobox 2 | 10109 | -0.055 | 0.0964 | No |
| 31 | TRPC1 | TRPC1 Entrez, Source | transient receptor potential cation channel, subfamily C, member 1 | 11040 | -0.074 | 0.0447 | No |
| 32 | CSF1R | CSF1R Entrez, Source | colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog | 11365 | -0.083 | 0.0407 | No |
| 33 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 12774 | -0.149 | -0.0286 | No |
| 34 | OTUD4 | OTUD4 Entrez, Source | OTU domain containing 4 | 13243 | -0.291 | 0.0074 | No |
