Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TPA_SENS_MIDDLE_UP |
| Enrichment Score (ES) | 0.6938362 |
| Normalized Enrichment Score (NES) | 2.1920652 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.0615567E-4 |
| FWER p-Value | 0.0020 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VIM | VIM Entrez, Source | vimentin | 6 | 0.953 | 0.1389 | Yes |
| 2 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 12 | 0.803 | 0.2558 | Yes |
| 3 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 69 | 0.494 | 0.3238 | Yes |
| 4 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 76 | 0.477 | 0.3930 | Yes |
| 5 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 130 | 0.390 | 0.4461 | Yes |
| 6 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 183 | 0.333 | 0.4909 | Yes |
| 7 | CYBA | CYBA Entrez, Source | cytochrome b-245, alpha polypeptide | 353 | 0.229 | 0.5116 | Yes |
| 8 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 358 | 0.227 | 0.5444 | Yes |
| 9 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 367 | 0.223 | 0.5764 | Yes |
| 10 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 560 | 0.171 | 0.5869 | Yes |
| 11 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 610 | 0.163 | 0.6071 | Yes |
| 12 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 663 | 0.156 | 0.6260 | Yes |
| 13 | HBEGF | HBEGF Entrez, Source | heparin-binding EGF-like growth factor | 717 | 0.149 | 0.6438 | Yes |
| 14 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 888 | 0.130 | 0.6500 | Yes |
| 15 | IL2RG | IL2RG Entrez, Source | interleukin 2 receptor, gamma (severe combined immunodeficiency) | 927 | 0.127 | 0.6657 | Yes |
| 16 | CCL7 | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 1159 | 0.111 | 0.6646 | Yes |
| 17 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 1208 | 0.109 | 0.6769 | Yes |
| 18 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 1327 | 0.103 | 0.6831 | Yes |
| 19 | PLD3 | PLD3 Entrez, Source | phospholipase D family, member 3 | 1454 | 0.096 | 0.6876 | Yes |
| 20 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 1550 | 0.092 | 0.6938 | Yes |
| 21 | AQP4 | AQP4 Entrez, Source | aquaporin 4 | 2061 | 0.071 | 0.6659 | No |
| 22 | ALOX5AP | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 2207 | 0.067 | 0.6647 | No |
| 23 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 3736 | 0.035 | 0.5549 | No |
| 24 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 4288 | 0.026 | 0.5172 | No |
| 25 | HSPA8 | HSPA8 Entrez, Source | heat shock 70kDa protein 8 | 4537 | 0.022 | 0.5017 | No |
| 26 | INHBA | INHBA Entrez, Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 4596 | 0.021 | 0.5004 | No |
| 27 | RHOH | RHOH Entrez, Source | ras homolog gene family, member H | 4918 | 0.016 | 0.4787 | No |
| 28 | RPS6KA1 | RPS6KA1 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 5670 | 0.006 | 0.4231 | No |
| 29 | CDC37 | CDC37 Entrez, Source | CDC37 cell division cycle 37 homolog (S. cerevisiae) | 5747 | 0.005 | 0.4181 | No |
| 30 | AGER | AGER Entrez, Source | advanced glycosylation end product-specific receptor | 5780 | 0.005 | 0.4164 | No |
| 31 | KCNN3 | KCNN3 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 | 6008 | 0.002 | 0.3996 | No |
| 32 | CLK3 | CLK3 Entrez, Source | CDC-like kinase 3 | 6374 | -0.003 | 0.3726 | No |
| 33 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 6928 | -0.010 | 0.3324 | No |
| 34 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 7062 | -0.011 | 0.3241 | No |
| 35 | AGA | AGA Entrez, Source | aspartylglucosaminidase | 7384 | -0.015 | 0.3022 | No |
| 36 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 7790 | -0.021 | 0.2747 | No |
| 37 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 9367 | -0.043 | 0.1624 | No |
| 38 | CCT5 | CCT5 Entrez, Source | chaperonin containing TCP1, subunit 5 (epsilon) | 9486 | -0.045 | 0.1601 | No |
| 39 | TSC22D1 | TSC22D1 Entrez, Source | TSC22 domain family, member 1 | 9967 | -0.053 | 0.1318 | No |
| 40 | IL1RN | IL1RN Entrez, Source | interleukin 1 receptor antagonist | 10196 | -0.057 | 0.1229 | No |
| 41 | PIK3CB | PIK3CB Entrez, Source | phosphoinositide-3-kinase, catalytic, beta polypeptide | 10639 | -0.065 | 0.0992 | No |
| 42 | PREP | PREP Entrez, Source | prolyl endopeptidase | 10771 | -0.068 | 0.0992 | No |
| 43 | DPP4 | DPP4 Entrez, Source | dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) | 10965 | -0.073 | 0.0953 | No |
| 44 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 11635 | -0.090 | 0.0581 | No |
| 45 | TAPBP | TAPBP Entrez, Source | TAP binding protein (tapasin) | 12109 | -0.108 | 0.0383 | No |
| 46 | SLC13A3 | SLC13A3 Entrez, Source | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 | 12834 | -0.156 | 0.0067 | No |
| 47 | NR0B2 | NR0B2 Entrez, Source | nuclear receptor subfamily 0, group B, member 2 | 13120 | -0.215 | 0.0167 | No |
