Details for gene set UVB_NHEK1

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in class	double_gel_8d
GeneSet	UVB_NHEK1_UP
Enrichment Score (ES)	0.5049105
Normalized Enrichment Score (NES)	1.8559927
Nominal p-value	0.0
FDR q-value	0.02273189
FWER p-Value	0.839

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IL1RL1	IL1RL1 Entrez, Source	interleukin 1 receptor-like 1	13	0.781	0.0751	Yes
2	CTGF	CTGF Entrez, Source	connective tissue growth factor	32	0.660	0.1381	Yes
3	ADM	ADM Entrez, Source	adrenomedullin	34	0.649	0.2012	Yes
4	HMGCS2	HMGCS2 Entrez, Source	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)	66	0.519	0.2494	Yes
5	CXCL2	CXCL2 Entrez, Source	chemokine (C-X-C motif) ligand 2	118	0.402	0.2848	Yes
6	CITED2	CITED2 Entrez, Source	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	145	0.367	0.3185	Yes
7	CCL20	CCL20 Entrez, Source	chemokine (C-C motif) ligand 20	160	0.355	0.3520	Yes
8	ATF3	ATF3 Entrez, Source	activating transcription factor 3	218	0.309	0.3779	Yes
9	SGK	SGK Entrez, Source	serum/glucocorticoid regulated kinase	330	0.237	0.3926	Yes
10	CYBA	CYBA Entrez, Source	cytochrome b-245, alpha polypeptide	353	0.229	0.4132	Yes
11	NEU1	NEU1 Entrez, Source	sialidase 1 (lysosomal sialidase)	510	0.181	0.4191	Yes
12	CYR61	CYR61 Entrez, Source	cysteine-rich, angiogenic inducer, 61	559	0.171	0.4321	Yes
13	IER3	IER3 Entrez, Source	immediate early response 3	598	0.165	0.4453	Yes
14	NR1D1	NR1D1 Entrez, Source	nuclear receptor subfamily 1, group D, member 1	688	0.151	0.4533	Yes
15	HBEGF	HBEGF Entrez, Source	heparin-binding EGF-like growth factor	717	0.149	0.4657	Yes
16	PHLDA1	PHLDA1 Entrez, Source	pleckstrin homology-like domain, family A, member 1	772	0.143	0.4755	Yes
17	GADD45B	GADD45B Entrez, Source	growth arrest and DNA-damage-inducible, beta	1045	0.118	0.4665	Yes
18	TRIB1	TRIB1 Entrez, Source	tribbles homolog 1 (Drosophila)	1067	0.116	0.4762	Yes
19	ITPR1	ITPR1 Entrez, Source	inositol 1,4,5-triphosphate receptor, type 1	1235	0.108	0.4741	Yes
20	ECHS1	ECHS1 Entrez, Source	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	1289	0.105	0.4803	Yes
21	IER2	IER2 Entrez, Source	immediate early response 2	1295	0.104	0.4901	Yes
22	DUSP1	DUSP1 Entrez, Source	dual specificity phosphatase 1	1297	0.104	0.5002	Yes
23	MYF6	MYF6 Entrez, Source	myogenic factor 6 (herculin)	1536	0.092	0.4912	Yes
24	GUK1	GUK1 Entrez, Source	guanylate kinase 1	1568	0.091	0.4977	Yes
25	ANXA2	ANXA2 Entrez, Source	annexin A2	1825	0.079	0.4861	Yes
26	TGFB1	TGFB1 Entrez, Source	transforming growth factor, beta 1 (Camurati-Engelmann disease)	2079	0.071	0.4739	Yes
27	CST6	CST6 Entrez, Source	cystatin E/M	2108	0.069	0.4785	Yes
28	TACSTD2	TACSTD2 Entrez, Source	tumor-associated calcium signal transducer 2	2200	0.067	0.4782	Yes
29	BCL2	BCL2 Entrez, Source	B-cell CLL/lymphoma 2	2324	0.064	0.4751	Yes
30	APOE	APOE Entrez, Source	apolipoprotein E	2345	0.063	0.4798	Yes
31	BTG1	BTG1 Entrez, Source	B-cell translocation gene 1, anti-proliferative	2350	0.063	0.4857	Yes
32	TITF1	TITF1 Entrez, Source	thyroid transcription factor 1	2354	0.063	0.4916	Yes
33	CLDN4	CLDN4 Entrez, Source	claudin 4	2429	0.061	0.4920	Yes
34	PSMD8	PSMD8 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	2441	0.061	0.4971	Yes
35	COL11A1	COL11A1 Entrez, Source	collagen, type XI, alpha 1	2472	0.060	0.5007	Yes
36	ACO2	ACO2 Entrez, Source	aconitase 2, mitochondrial	2544	0.059	0.5011	Yes
37	GAST	GAST Entrez, Source	gastrin	2569	0.058	0.5049	Yes
38	CDH16	CDH16 Entrez, Source	cadherin 16, KSP-cadherin	3141	0.046	0.4662	No
39	CLTB	CLTB Entrez, Source	clathrin, light chain (Lcb)	3232	0.044	0.4637	No
40	MAP1LC3B	MAP1LC3B Entrez, Source	microtubule-associated protein 1 light chain 3 beta	3406	0.040	0.4546	No
41	UQCRB	UQCRB Entrez, Source	ubiquinol-cytochrome c reductase binding protein	3490	0.039	0.4521	No
42	CHRNB1	CHRNB1 Entrez, Source	cholinergic receptor, nicotinic, beta 1 (muscle)	3852	0.033	0.4280	No
43	CCNA1	CCNA1 Entrez, Source	cyclin A1	3861	0.032	0.4305	No
44	MMP10	MMP10 Entrez, Source	matrix metallopeptidase 10 (stromelysin 2)	4140	0.028	0.4123	No
45	TAGLN3	TAGLN3 Entrez, Source	transgelin 3	4191	0.027	0.4111	No
46	CAPNS1	CAPNS1 Entrez, Source	calpain, small subunit 1	4237	0.026	0.4103	No
47	PIK3R3	PIK3R3 Entrez, Source	phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)	4251	0.026	0.4119	No
48	COX7A2	COX7A2 Entrez, Source	cytochrome c oxidase subunit VIIa polypeptide 2 (liver)	4338	0.025	0.4078	No
49	STXBP2	STXBP2 Entrez, Source	syntaxin binding protein 2	4370	0.024	0.4078	No
50	HCRT	HCRT Entrez, Source	hypocretin (orexin) neuropeptide precursor	4555	0.022	0.3960	No
51	MNAT1	MNAT1 Entrez, Source	menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)	4556	0.022	0.3981	No
52	DSCR1L1	DSCR1L1 Entrez, Source	Down syndrome critical region gene 1-like 1	4800	0.018	0.3816	No
53	IL6	IL6 Entrez, Source	interleukin 6 (interferon, beta 2)	4953	0.016	0.3716	No
54	GAD2	GAD2 Entrez, Source	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	5140	0.013	0.3589	No
55	CCK	CCK Entrez, Source	cholecystokinin	5395	0.010	0.3406	No
56	PPBP	PPBP Entrez, Source	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	5643	0.006	0.3226	No
57	SCG5	SCG5 Entrez, Source	secretogranin V (7B2 protein)	5677	0.006	0.3207	No
58	GADD45A	GADD45A Entrez, Source	growth arrest and DNA-damage-inducible, alpha	5788	0.005	0.3128	No
59	BRD2	BRD2 Entrez, Source	bromodomain containing 2	5876	0.004	0.3066	No
60	PPIF	PPIF Entrez, Source	peptidylprolyl isomerase F (cyclophilin F)	5913	0.003	0.3042	No
61	YKT6	YKT6 Entrez, Source	YKT6 v-SNARE homolog (S. cerevisiae)	6368	-0.003	0.2701	No
62	IGFBP6	IGFBP6 Entrez, Source	insulin-like growth factor binding protein 6	6428	-0.004	0.2660	No
63	JUND	JUND Entrez, Source	jun D proto-oncogene	6457	-0.004	0.2643	No
64	GPI	GPI Entrez, Source	glucose phosphate isomerase	6561	-0.005	0.2570	No
65	DYNLL1	DYNLL1 Entrez, Source	dynein, light chain, LC8-type 1	7062	-0.011	0.2204	No
66	RAP1A	RAP1A Entrez, Source	RAP1A, member of RAS oncogene family	7119	-0.012	0.2173	No
67	PFN1	PFN1 Entrez, Source	profilin 1	7229	-0.013	0.2104	No
68	KYNU	KYNU Entrez, Source	kynureninase (L-kynurenine hydrolase)	7289	-0.014	0.2073	No
69	EEF1A1	EEF1A1 Entrez, Source	eukaryotic translation elongation factor 1 alpha 1	7536	-0.017	0.1904	No
70	RALY	RALY Entrez, Source	RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))	7633	-0.019	0.1849	No
71	ATP5I	ATP5I Entrez, Source	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E	7717	-0.020	0.1806	No
72	CHRNB4	CHRNB4 Entrez, Source	cholinergic receptor, nicotinic, beta 4	8094	-0.025	0.1546	No
73	TOB1	TOB1 Entrez, Source	transducer of ERBB2, 1	8322	-0.028	0.1402	No
74	PDLIM5	PDLIM5 Entrez, Source	PDZ and LIM domain 5	8373	-0.029	0.1392	No
75	BCL2L11	BCL2L11 Entrez, Source	BCL2-like 11 (apoptosis facilitator)	8410	-0.030	0.1394	No
76	BAMBI	BAMBI Entrez, Source	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)	8540	-0.031	0.1327	No
77	HSP90AB1	HSP90AB1 Entrez, Source	heat shock protein 90kDa alpha (cytosolic), class B member 1	8666	-0.033	0.1265	No
78	H2AFX	H2AFX Entrez, Source	H2A histone family, member X	8894	-0.036	0.1128	No
79	ARHGDIA	ARHGDIA Entrez, Source	Rho GDP dissociation inhibitor (GDI) alpha	9058	-0.038	0.1043	No
80	RPS17	RPS17 Entrez, Source	ribosomal protein S17	9118	-0.039	0.1036	No
81	PGK1	PGK1 Entrez, Source	phosphoglycerate kinase 1	9144	-0.039	0.1056	No
82	TOM1	TOM1 Entrez, Source	target of myb1 (chicken)	9160	-0.040	0.1083	No
83	PPP2R1A	PPP2R1A Entrez, Source	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	9245	-0.041	0.1059	No
84	PAX8	PAX8 Entrez, Source	paired box gene 8	9468	-0.044	0.0935	No
85	CRYBA4	CRYBA4 Entrez, Source	crystallin, beta A4	9477	-0.045	0.0972	No
86	PCTK1	PCTK1 Entrez, Source	PCTAIRE protein kinase 1	9584	-0.047	0.0938	No
87	SURF1	SURF1 Entrez, Source	surfeit 1	9722	-0.049	0.0882	No
88	RPL37	RPL37 Entrez, Source	ribosomal protein L37	9799	-0.050	0.0873	No
89	TSC22D1	TSC22D1 Entrez, Source	TSC22 domain family, member 1	9967	-0.053	0.0799	No
90	RPS2	RPS2 Entrez, Source	ribosomal protein S2	10123	-0.056	0.0736	No
91	RPL31	RPL31 Entrez, Source	ribosomal protein L31	10162	-0.056	0.0762	No
92	RPS21	RPS21 Entrez, Source	ribosomal protein S21	10407	-0.060	0.0636	No
93	HTR4	HTR4 Entrez, Source	5-hydroxytryptamine (serotonin) receptor 4	10483	-0.062	0.0640	No
94	NDUFA1	NDUFA1 Entrez, Source	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa	10602	-0.064	0.0613	No
95	S100A9	S100A9 Entrez, Source	S100 calcium binding protein A9	10706	-0.066	0.0600	No
96	RPS23	RPS23 Entrez, Source	ribosomal protein S23	10900	-0.071	0.0523	No
97	CXCR3	CXCR3 Entrez, Source	chemokine (C-X-C motif) receptor 3	10944	-0.072	0.0561	No
98	RPS27	RPS27 Entrez, Source	ribosomal protein S27 (metallopanstimulin 1)	11258	-0.080	0.0402	No
99	EIF3S4	EIF3S4 Entrez, Source	eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa	11289	-0.081	0.0459	No
100	NR4A2	NR4A2 Entrez, Source	nuclear receptor subfamily 4, group A, member 2	11567	-0.088	0.0336	No
101	CEACAM1	CEACAM1 Entrez, Source	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	11634	-0.090	0.0373	No
102	TUBB3	TUBB3 Entrez, Source	tubulin, beta 3	11724	-0.093	0.0396	No
103	SPINK1	SPINK1 Entrez, Source	serine peptidase inhibitor, Kazal type 1	12063	-0.106	0.0244	No
104	CSRP1	CSRP1 Entrez, Source	cysteine and glycine-rich protein 1	12583	-0.134	-0.0018	No
105	MAOB	MAOB Entrez, Source	monoamine oxidase B	12987	-0.180	-0.0146	No
106	ID2	ID2 Entrez, Source	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	13029	-0.193	0.0011	No
107	HIST2H2AA3	HIST2H2AA3 Entrez, Source	histone cluster 2, H2aa3	13163	-0.231	0.0135	No