Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_8d
GeneSetUVB_NHEK3_ALL
Enrichment Score (ES)0.4361821
Normalized Enrichment Score (NES)1.801865
Nominal p-value0.0
FDR q-value0.03201514
FWER p-Value0.969
Table: GSEA Results Summary



Fig 1: Enrichment plot: UVB_NHEK3_ALL   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ANXA1ANXA1
Entrez,  Source
annexin A1100.8150.0334Yes
2CCND2CCND2
Entrez,  Source
cyclin D2110.8150.0675Yes
3COL5A2COL5A2
Entrez,  Source
collagen, type V, alpha 2280.6680.0943Yes
4CTGFCTGF
Entrez,  Source
connective tissue growth factor320.6600.1217Yes
5ADMADM
Entrez,  Source
adrenomedullin340.6490.1488Yes
6EMP1EMP1
Entrez,  Source
epithelial membrane protein 1440.6060.1735Yes
7IL1R2IL1R2
Entrez,  Source
interleukin 1 receptor, type II460.5990.1985Yes
8PFKPPFKP
Entrez,  Source
phosphofructokinase, platelet520.5760.2222Yes
9GDF15GDF15
Entrez,  Source
growth differentiation factor 15580.5590.2453Yes
10PTPRZ1PTPRZ1
Entrez,  Source
protein tyrosine phosphatase, receptor-type, Z polypeptide 1650.5230.2667Yes
11ITGB4ITGB4
Entrez,  Source
integrin, beta 41210.4010.2793Yes
12CRYABCRYAB
Entrez,  Source
crystallin, alpha B1410.3710.2934Yes
13CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 21450.3670.3085Yes
14HK1HK1
Entrez,  Source
hexokinase 11970.3230.3181Yes
15ATF3ATF3
Entrez,  Source
activating transcription factor 32180.3090.3296Yes
16SLC31A2SLC31A2
Entrez,  Source
solute carrier family 31 (copper transporters), member 22680.2670.3370Yes
17CD9CD9
Entrez,  Source
CD9 molecule2990.2500.3452Yes
18JAG1JAG1
Entrez,  Source
jagged 1 (Alagille syndrome)3230.2390.3534Yes
19RND3RND3
Entrez,  Source
Rho family GTPase 33500.2300.3611Yes
20LTBP1LTBP1
Entrez,  Source
latent transforming growth factor beta binding protein 13720.2190.3686Yes
21F3F3
Entrez,  Source
coagulation factor III (thromboplastin, tissue factor)4180.2050.3738Yes
22ABCD3ABCD3
Entrez,  Source
ATP-binding cassette, sub-family D (ALD), member 34510.1950.3795Yes
23PRSS8PRSS8
Entrez,  Source
protease, serine, 8 (prostasin)4900.1830.3843Yes
24TPBGTPBG
Entrez,  Source
trophoblast glycoprotein5030.1820.3909Yes
25NEU1NEU1
Entrez,  Source
sialidase 1 (lysosomal sialidase)5100.1810.3981Yes
26DUSP5DUSP5
Entrez,  Source
dual specificity phosphatase 55530.1720.4020Yes
27CYR61CYR61
Entrez,  Source
cysteine-rich, angiogenic inducer, 615590.1710.4088Yes
28SCRN1SCRN1
Entrez,  Source
secernin 15680.1700.4153Yes
29IER3IER3
Entrez,  Source
immediate early response 35980.1650.4200Yes
30ALCAMALCAM
Entrez,  Source
activated leukocyte cell adhesion molecule6460.1580.4231Yes
31HBEGFHBEGF
Entrez,  Source
heparin-binding EGF-like growth factor7170.1490.4239Yes
32MYH10MYH10
Entrez,  Source
myosin, heavy chain 10, non-muscle7440.1450.4280Yes
33TAX1BP3TAX1BP3
Entrez,  Source
Tax1 (human T-cell leukemia virus type I) binding protein 37910.1400.4304Yes
34PLA2G4APLA2G4A
Entrez,  Source
phospholipase A2, group IVA (cytosolic, calcium-dependent)8120.1390.4347Yes
35NFKBIANFKBIA
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha8880.1300.4344Yes
36TPMTTPMT
Entrez,  Source
thiopurine S-methyltransferase9800.1230.4326Yes
37LIFLIF
Entrez,  Source
leukemia inhibitory factor (cholinergic differentiation factor)10370.1180.4332Yes
38BNIP3BNIP3
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 311770.1110.4272Yes
39SLC2A1SLC2A1
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 112120.1090.4292Yes
40EPHX2EPHX2
Entrez,  Source
epoxide hydrolase 2, cytoplasmic12220.1080.4330Yes
41IER2IER2
Entrez,  Source
immediate early response 212950.1040.4319Yes
42DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 112970.1040.4362Yes
43HMGA2HMGA2
Entrez,  Source
high mobility group AT-hook 214650.0960.4274No
44VGLL4VGLL4
Entrez,  Source
vestigial like 4 (Drosophila)15000.0940.4287No
45HMGB1HMGB1
Entrez,  Source
high-mobility group box 115820.0900.4263No
46ABCC1ABCC1
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 115830.0900.4301No
47TRIP10TRIP10
Entrez,  Source
thyroid hormone receptor interactor 1017630.0820.4198No
48PLCD1PLCD1
Entrez,  Source
phospholipase C, delta 118990.0770.4127No
49HSD17B4HSD17B4
Entrez,  Source
hydroxysteroid (17-beta) dehydrogenase 419100.0760.4151No
50FGFBP1FGFBP1
Entrez,  Source
fibroblast growth factor binding protein 120720.0710.4057No
51CST6CST6
Entrez,  Source
cystatin E/M21080.0690.4060No
52DUSP4DUSP4
Entrez,  Source
dual specificity phosphatase 421620.0680.4048No
53VSNL1VSNL1
Entrez,  Source
visinin-like 121690.0680.4072No
54ID3ID3
Entrez,  Source
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein21810.0680.4092No
55PTP4A1PTP4A1
Entrez,  Source
protein tyrosine phosphatase type IVA, member 121840.0680.4118No
56CXADRCXADR
Entrez,  Source
coxsackie virus and adenovirus receptor22310.0660.4111No
57PON2PON2
Entrez,  Source
paraoxonase 223080.0640.4080No
58GNAI1GNAI1
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 124240.0610.4017No
59GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta24790.0600.4001No
60SP3SP3
Entrez,  Source
Sp3 transcription factor25120.0590.4002No
61ARL6IP1ARL6IP1
Entrez,  Source
ADP-ribosylation factor-like 6 interacting protein 125270.0590.4016No
62ACO2ACO2
Entrez,  Source
aconitase 2, mitochondrial25440.0590.4028No
63CYB5ACYB5A
Entrez,  Source
cytochrome b5 type A (microsomal)25950.0580.4014No
64ASS1ASS1
Entrez,  Source
argininosuccinate synthetase 126500.0560.3996No
65GLG1GLG1
Entrez,  Source
golgi apparatus protein 127290.0540.3959No
66PSMA6PSMA6
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 627340.0540.3979No
67R3HDM1R3HDM1
Entrez,  Source
R3H domain containing 128570.0520.3907No
68CDC25BCDC25B
Entrez,  Source
cell division cycle 25B30660.0470.3768No
69DAZAP2DAZAP2
Entrez,  Source
DAZ associated protein 231090.0460.3755No
70GTF2BGTF2B
Entrez,  Source
general transcription factor IIB31400.0460.3751No
71ACSL1ACSL1
Entrez,  Source
acyl-CoA synthetase long-chain family member 132160.0440.3712No
72APPAPP
Entrez,  Source
amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)32980.0430.3668No
73MRPL49MRPL49
Entrez,  Source
mitochondrial ribosomal protein L4934630.0390.3559No
74MYD88MYD88
Entrez,  Source
myeloid differentiation primary response gene (88)34710.0390.3570No
75RNF4RNF4
Entrez,  Source
ring finger protein 435800.0370.3503No
76KIAA0101KIAA0101
Entrez,  Source
KIAA010135930.0370.3509No
77GTF2A2GTF2A2
Entrez,  Source
general transcription factor IIA, 2, 12kDa36150.0370.3508No
78ITGB5ITGB5
Entrez,  Source
integrin, beta 537140.0350.3448No
79CBFBCBFB
Entrez,  Source
core-binding factor, beta subunit38530.0320.3356No
80CELSR2CELSR2
Entrez,  Source
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)38800.0320.3349No
81CD99CD99
Entrez,  Source
CD99 molecule38910.0320.3355No
82KPNA2KPNA2
Entrez,  Source
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)41090.0290.3201No
83PGRMC1PGRMC1
Entrez,  Source
progesterone receptor membrane component 141360.0280.3193No
84MMP10MMP10
Entrez,  Source
matrix metallopeptidase 10 (stromelysin 2)41400.0280.3202No
85OAS1OAS1
Entrez,  Source
2',5'-oligoadenylate synthetase 1, 40/46kDa41500.0280.3207No
86PPP2CBPPP2CB
Entrez,  Source
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform41660.0280.3207No
87MAD2L1BPMAD2L1BP
Entrez,  Source
MAD2L1 binding protein41900.0270.3201No
88CDK5CDK5
Entrez,  Source
cyclin-dependent kinase 543040.0250.3125No
89MAP2K3MAP2K3
Entrez,  Source
mitogen-activated protein kinase kinase 343210.0250.3124No
90TAF9TAF9
Entrez,  Source
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa43220.0250.3134No
91PRDX6PRDX6
Entrez,  Source
peroxiredoxin 644300.0230.3062No
92TRAM1TRAM1
Entrez,  Source
translocation associated membrane protein 145810.0210.2956No
93CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)46390.0200.2921No
94HSP90AA1HSP90AA1
Entrez,  Source
heat shock protein 90kDa alpha (cytosolic), class A member 146550.0200.2918No
95ATF4ATF4
Entrez,  Source
activating transcription factor 4 (tax-responsive enhancer element B67)46620.0200.2922No
96TOMM20TOMM20
Entrez,  Source
translocase of outer mitochondrial membrane 20 homolog (yeast)47570.0190.2858No
97ST6GALNAC2ST6GALNAC2
Entrez,  Source
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 247650.0190.2860No
98ATP1B1ATP1B1
Entrez,  Source
ATPase, Na+/K+ transporting, beta 1 polypeptide47880.0180.2851No
99TNFRSF1ATNFRSF1A
Entrez,  Source
tumor necrosis factor receptor superfamily, member 1A47940.0180.2855No
100CLINT1CLINT1
Entrez,  Source
clathrin interactor 148850.0170.2793No
101HIF1AHIF1A
Entrez,  Source
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)48920.0170.2796No
102NMT1NMT1
Entrez,  Source
N-myristoyltransferase 149050.0170.2793No
103LCN2LCN2
Entrez,  Source
lipocalin 2 (oncogene 24p3)49340.0160.2779No
104PPP2R2APPP2R2A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform49680.0160.2760No
105FNTAFNTA
Entrez,  Source
farnesyltransferase, CAAX box, alpha49850.0150.2754No
106WWP1WWP1
Entrez,  Source
WW domain containing E3 ubiquitin protein ligase 149860.0150.2761No
107GTF3C2GTF3C2
Entrez,  Source
general transcription factor IIIC, polypeptide 2, beta 110kDa51780.0130.2620No
108FHL1FHL1
Entrez,  Source
four and a half LIM domains 152660.0120.2558No
109CEBPDCEBPD
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), delta52680.0120.2562No
110EIF2B1EIF2B1
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa53400.0110.2512No
111QSCN6QSCN6
Entrez,  Source
quiescin Q653850.0100.2483No
112DR1DR1
Entrez,  Source
down-regulator of transcription 1, TBP-binding (negative cofactor 2)54790.0090.2415No
113PAMPAM
Entrez,  Source
peptidylglycine alpha-amidating monooxygenase55010.0080.2403No
114PTGS1PTGS1
Entrez,  Source
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)55360.0080.2380No
115BPGMBPGM
Entrez,  Source
2,3-bisphosphoglycerate mutase56000.0070.2335No
116PPIBPPIB
Entrez,  Source
peptidylprolyl isomerase B (cyclophilin B)57130.0060.2251No
117PFN2PFN2
Entrez,  Source
profilin 257380.0050.2235No
118CDC37CDC37
Entrez,  Source
CDC37 cell division cycle 37 homolog (S. cerevisiae)57470.0050.2231No
119GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha57880.0050.2202No
120COPS2COPS2
Entrez,  Source
COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)58560.0040.2153No
121WBSCR1WBSCR1
Entrez,  Source
Williams-Beuren syndrome chromosome region 158630.0040.2150No
122BRD2BRD2
Entrez,  Source
bromodomain containing 258760.0040.2142No
123CSNK2A1CSNK2A1
Entrez,  Source
casein kinase 2, alpha 1 polypeptide58980.0030.2127No
124PPIFPPIF
Entrez,  Source
peptidylprolyl isomerase F (cyclophilin F)59130.0030.2118No
125DSC2DSC2
Entrez,  Source
desmocollin 260670.0010.2001No
126HSPH1HSPH1
Entrez,  Source
heat shock 105kDa/110kDa protein 161270.0000.1956No
127ITGB1ITGB1
Entrez,  Source
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)6253-0.0010.1861No
128RELARELA
Entrez,  Source
v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)6260-0.0010.1857No
129ATP1B3ATP1B3
Entrez,  Source
ATPase, Na+/K+ transporting, beta 3 polypeptide6301-0.0020.1827No
130ATP6V0CATP6V0C
Entrez,  Source
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c6333-0.0020.1805No
131MALLMALL
Entrez,  Source
mal, T-cell differentiation protein-like6400-0.0030.1755No
132LAMA3LAMA3
Entrez,  Source
laminin, alpha 36404-0.0030.1754No
133TGFBITGFBI
Entrez,  Source
transforming growth factor, beta-induced, 68kDa6410-0.0030.1752No
134STXBP3STXBP3
Entrez,  Source
syntaxin binding protein 36429-0.0040.1740No
135JUNDJUND
Entrez,  Source
jun D proto-oncogene6457-0.0040.1721No
136UBE2G1UBE2G1
Entrez,  Source
ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)6486-0.0040.1701No
137PSMA4PSMA4
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 46523-0.0050.1675No
138PSMC2PSMC2
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 26594-0.0060.1624No
139PPP1CCPPP1CC
Entrez,  Source
protein phosphatase 1, catalytic subunit, gamma isoform6696-0.0070.1550No
140TFRCTFRC
Entrez,  Source
transferrin receptor (p90, CD71)6700-0.0070.1550No
141GPIAP1GPIAP1
Entrez,  Source
GPI-anchored membrane protein 16728-0.0070.1533No
142CBR1CBR1
Entrez,  Source
carbonyl reductase 16731-0.0070.1535No
143TMED10TMED10
Entrez,  Source
transmembrane emp24-like trafficking protein 10 (yeast)6770-0.0080.1509No
144TFPI2TFPI2
Entrez,  Source
tissue factor pathway inhibitor 26771-0.0080.1512No
145GALNT3GALNT3
Entrez,  Source
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)6927-0.0100.1397No
146TCEB1TCEB1
Entrez,  Source
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)6931-0.0100.1399No
147ITGA6ITGA6
Entrez,  Source
integrin, alpha 66967-0.0100.1377No
148CKAP5CKAP5
Entrez,  Source
cytoskeleton associated protein 57020-0.0110.1342No
149ME1ME1
Entrez,  Source
malic enzyme 1, NADP(+)-dependent, cytosolic7060-0.0110.1317No
150DYNLL1DYNLL1
Entrez,  Source
dynein, light chain, LC8-type 17062-0.0110.1321No
151STK25STK25
Entrez,  Source
serine/threonine kinase 25 (STE20 homolog, yeast)7067-0.0110.1322No
152TJP2TJP2
Entrez,  Source
tight junction protein 2 (zona occludens 2)7094-0.0120.1307No
153SFRS9SFRS9
Entrez,  Source
splicing factor, arginine/serine-rich 97120-0.0120.1293No
154CIRBPCIRBP
Entrez,  Source
cold inducible RNA binding protein7213-0.0130.1228No
155EPS15EPS15
Entrez,  Source
epidermal growth factor receptor pathway substrate 157217-0.0130.1232No
156PPP3CAPPP3CA
Entrez,  Source
protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)7318-0.0140.1161No
157SEPT2SEPT2
Entrez,  Source
septin 27427-0.0160.1085No
158UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase7435-0.0160.1086No
159COPS8COPS8
Entrez,  Source
COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)7463-0.0160.1073No
160SONSON
Entrez,  Source
SON DNA binding protein7481-0.0160.1066No
161VDAC2VDAC2
Entrez,  Source
voltage-dependent anion channel 27498-0.0170.1061No
162SAFBSAFB
Entrez,  Source
scaffold attachment factor B7539-0.0170.1038No
163KCNK1KCNK1
Entrez,  Source
potassium channel, subfamily K, member 17542-0.0170.1043No
164RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 17552-0.0170.1044No
165MMEMME
Entrez,  Source
membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)7620-0.0180.1000No
166KIF5BKIF5B
Entrez,  Source
kinesin family member 5B7649-0.0190.0987No
167DNAJA1DNAJA1
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily A, member 17683-0.0190.0969No
168MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)7715-0.0200.0954No
169ATP5OATP5O
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)7722-0.0200.0957No
170STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)7752-0.0200.0944No
171RFC1RFC1
Entrez,  Source
replication factor C (activator 1) 1, 145kDa7792-0.0210.0922No
172MCFD2MCFD2
Entrez,  Source
multiple coagulation factor deficiency 27916-0.0220.0838No
173ZNF148ZNF148
Entrez,  Source
zinc finger protein 1487943-0.0230.0827No
174ADKADK
Entrez,  Source
adenosine kinase7944-0.0230.0837No
175SAP18SAP18
Entrez,  Source
Sin3A-associated protein, 18kDa7954-0.0230.0839No
176RAD23BRAD23B
Entrez,  Source
RAD23 homolog B (S. cerevisiae)7961-0.0230.0844No
177CDKN1ACDKN1A
Entrez,  Source
cyclin-dependent kinase inhibitor 1A (p21, Cip1)7976-0.0230.0843No
178UBE2IUBE2I
Entrez,  Source
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)8006-0.0240.0831No
179TSG101TSG101
Entrez,  Source
tumor susceptibility gene 1018034-0.0240.0820No
180MAPK6MAPK6
Entrez,  Source
mitogen-activated protein kinase 68081-0.0250.0796No
181RRAGARRAGA
Entrez,  Source
Ras-related GTP binding A8100-0.0250.0792No
182USP10USP10
Entrez,  Source
ubiquitin specific peptidase 108103-0.0250.0801No
183PSMC1PSMC1
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 18118-0.0250.0801No
184CCNG1CCNG1
Entrez,  Source
cyclin G18130-0.0260.0803No
185SDHASDHA
Entrez,  Source
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)8238-0.0270.0733No
186PSMC6PSMC6
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 68252-0.0270.0734No
187PPP4R1PPP4R1
Entrez,  Source
protein phosphatase 4, regulatory subunit 18256-0.0270.0743No
188HNRPKHNRPK
Entrez,  Source
heterogeneous nuclear ribonucleoprotein K8260-0.0270.0752No
189MYST3MYST3
Entrez,  Source
MYST histone acetyltransferase (monocytic leukemia) 38296-0.0280.0737No
190EIF2S1EIF2S1
Entrez,  Source
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa8354-0.0290.0706No
191PSMD6PSMD6
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 68376-0.0290.0702No
192CTR9CTR9
Entrez,  Source
Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)8385-0.0290.0708No
193EIF4G2EIF4G2
Entrez,  Source
eukaryotic translation initiation factor 4 gamma, 28447-0.0300.0673No
194ARL4AARL4A
Entrez,  Source
ADP-ribosylation factor-like 4A8475-0.0310.0666No
195GSK3AGSK3A
Entrez,  Source
glycogen synthase kinase 3 alpha8514-0.0310.0649No
196BAMBIBAMBI
Entrez,  Source
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)8540-0.0310.0643No
197FLNBFLNB
Entrez,  Source
filamin B, beta (actin binding protein 278)8603-0.0320.0609No
198ATICATIC
Entrez,  Source
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase8726-0.0340.0530No
199GPX2GPX2
Entrez,  Source
glutathione peroxidase 2 (gastrointestinal)8829-0.0350.0467No
200CNN3CNN3
Entrez,  Source
calponin 3, acidic8886-0.0360.0439No
201ACY1ACY1
Entrez,  Source
aminoacylase 18889-0.0360.0453No
202H2AFXH2AFX
Entrez,  Source
H2A histone family, member X8894-0.0360.0465No
203GSPT1GSPT1
Entrez,  Source
G1 to S phase transition 18969-0.0370.0424No
204USP11USP11
Entrez,  Source
ubiquitin specific peptidase 119055-0.0380.0375No
205CLTACLTA
Entrez,  Source
clathrin, light chain (Lca)9172-0.0400.0303No
206RPL3RPL3
Entrez,  Source
ribosomal protein L39257-0.0410.0256No
207THBS2THBS2
Entrez,  Source
thrombospondin 29270-0.0410.0264No
208POLD2POLD2
Entrez,  Source
polymerase (DNA directed), delta 2, regulatory subunit 50kDa9276-0.0410.0277No
209PTPN12PTPN12
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 129303-0.0420.0275No
210RAB2RAB2
Entrez,  Source
RAB2, member RAS oncogene family9314-0.0420.0285No
211IL4RIL4R
Entrez,  Source
interleukin 4 receptor9332-0.0420.0289No
212PKN2PKN2
Entrez,  Source
protein kinase N29361-0.0430.0286No
213CALB2CALB2
Entrez,  Source
calbindin 2, 29kDa (calretinin)9436-0.0440.0247No
214PTPRFPTPRF
Entrez,  Source
protein tyrosine phosphatase, receptor type, F9495-0.0450.0222No
215PTPRKPTPRK
Entrez,  Source
protein tyrosine phosphatase, receptor type, K9501-0.0450.0237No
216PSMA5PSMA5
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 59533-0.0460.0232No
217RASA1RASA1
Entrez,  Source
RAS p21 protein activator (GTPase activating protein) 19586-0.0470.0212No
218UBXD2UBXD2
Entrez,  Source
UBX domain containing 29639-0.0480.0192No
219SLC39A6SLC39A6
Entrez,  Source
solute carrier family 39 (zinc transporter), member 69664-0.0480.0194No
220AKR1A1AKR1A1
Entrez,  Source
aldo-keto reductase family 1, member A1 (aldehyde reductase)9857-0.0510.0068No
221TSC22D1TSC22D1
Entrez,  Source
TSC22 domain family, member 19967-0.0530.0007No
222NFE2L2NFE2L2
Entrez,  Source
nuclear factor (erythroid-derived 2)-like 210005-0.0540.0001No
223PCMT1PCMT1
Entrez,  Source
protein-L-isoaspartate (D-aspartate) O-methyltransferase10182-0.056-0.0110No
224IL1RNIL1RN
Entrez,  Source
interleukin 1 receptor antagonist10196-0.057-0.0096No
225PGM1PGM1
Entrez,  Source
phosphoglucomutase 110277-0.058-0.0133No
226PBEF1PBEF1
Entrez,  Source
pre-B-cell colony enhancing factor 110279-0.058-0.0109No
227UBE2V2UBE2V2
Entrez,  Source
ubiquitin-conjugating enzyme E2 variant 210326-0.059-0.0120No
228ALDH9A1ALDH9A1
Entrez,  Source
aldehyde dehydrogenase 9 family, member A110414-0.060-0.0161No
229RSNRSN
Entrez,  Source
restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)10454-0.061-0.0165No
230GLULGLUL
Entrez,  Source
glutamate-ammonia ligase (glutamine synthetase)10574-0.064-0.0230No
231FBN2FBN2
Entrez,  Source
fibrillin 2 (congenital contractural arachnodactyly)10607-0.064-0.0227No
232ATP6V1B2ATP6V1B2
Entrez,  Source
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B210631-0.065-0.0218No
233VEGFVEGF
Entrez,  Source
vascular endothelial growth factor10686-0.066-0.0231No
234ATP6V0D1ATP6V0D1
Entrez,  Source
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d110697-0.066-0.0211No
235PREPPREP
Entrez,  Source
prolyl endopeptidase10771-0.068-0.0239No
236UBE2D2UBE2D2
Entrez,  Source
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)10785-0.068-0.0220No
237STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa10803-0.068-0.0205No
238CDKN3CDKN3
Entrez,  Source
cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase)10809-0.069-0.0180No
239EXOSC7EXOSC7
Entrez,  Source
exosome component 710861-0.070-0.0190No
240SLC7A5SLC7A5
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 510889-0.071-0.0181No
241ASNSASNS
Entrez,  Source
asparagine synthetase11024-0.074-0.0252No
242RPS24RPS24
Entrez,  Source
ribosomal protein S2411160-0.077-0.0323No
243PYGLPYGL
Entrez,  Source
phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI)11176-0.078-0.0302No
244CDC20CDC20
Entrez,  Source
CDC20 cell division cycle 20 homolog (S. cerevisiae)11187-0.078-0.0277No
245MTHFD1MTHFD1
Entrez,  Source
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase11282-0.081-0.0316No
246CTSCCTSC
Entrez,  Source
cathepsin C11373-0.083-0.0349No
247YY1YY1
Entrez,  Source
YY1 transcription factor11474-0.086-0.0390No
248DDX39DDX39
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3911591-0.089-0.0442No
249PIM1PIM1
Entrez,  Source
pim-1 oncogene11624-0.090-0.0429No
250RAB21RAB21
Entrez,  Source
RAB21, member RAS oncogene family11632-0.090-0.0397No
251DUTDUT
Entrez,  Source
dUTP pyrophosphatase11707-0.092-0.0415No
252FDFT1FDFT1
Entrez,  Source
farnesyl-diphosphate farnesyltransferase 111716-0.093-0.0382No
253AARSAARS
Entrez,  Source
alanyl-tRNA synthetase11763-0.094-0.0378No
254DDX1DDX1
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 111880-0.098-0.0425No
255PSME4PSME4
Entrez,  Source
proteasome (prosome, macropain) activator subunit 412096-0.107-0.0545No
256SLKSLK
Entrez,  Source
STE20-like kinase (yeast)12099-0.107-0.0502No
257ETF1ETF1
Entrez,  Source
eukaryotic translation termination factor 112179-0.110-0.0516No
258YARSYARS
Entrez,  Source
tyrosyl-tRNA synthetase12233-0.113-0.0509No
259XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)12235-0.113-0.0463No
260EPRSEPRS
Entrez,  Source
glutamyl-prolyl-tRNA synthetase12268-0.115-0.0439No
261HMOX1HMOX1
Entrez,  Source
heme oxygenase (decycling) 112319-0.117-0.0429No
262GJB2GJB2
Entrez,  Source
gap junction protein, beta 2, 26kDa (connexin 26)12323-0.117-0.0382No
263SOX9SOX9
Entrez,  Source
SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)12395-0.121-0.0385No
264BLVRABLVRA
Entrez,  Source
biliverdin reductase A12414-0.122-0.0348No
265HNRPUHNRPU
Entrez,  Source
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)12429-0.123-0.0307No
266TIAM1TIAM1
Entrez,  Source
T-cell lymphoma invasion and metastasis 112504-0.128-0.0310No
267ANKRD15ANKRD15
Entrez,  Source
ankyrin repeat domain 1512561-0.132-0.0298No
268MMP9MMP9
Entrez,  Source
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)12642-0.137-0.0302No
269DHCR24DHCR24
Entrez,  Source
24-dehydrocholesterol reductase12656-0.138-0.0254No
270XBP1XBP1
Entrez,  Source
X-box binding protein 112661-0.138-0.0199No
271RBP1RBP1
Entrez,  Source
retinol binding protein 1, cellular12674-0.139-0.0150No
272XRCC6XRCC6
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa)12731-0.144-0.0132No
273FGFR3FGFR3
Entrez,  Source
fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)12848-0.158-0.0155No
274GCLCGCLC
Entrez,  Source
glutamate-cysteine ligase, catalytic subunit12866-0.161-0.0101No
275SRD5A1SRD5A1
Entrez,  Source
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)12915-0.167-0.0067No
276LTB4DHLTB4DH
Entrez,  Source
leukotriene B4 12-hydroxydehydrogenase13092-0.207-0.0115No
277HNRPA1HNRPA1
Entrez,  Source
heterogeneous nuclear ribonucleoprotein A113096-0.208-0.0030No
278HIST2H2AA3HIST2H2AA3
Entrez,  Source
histone cluster 2, H2aa313163-0.2310.0016No
279FASNFASN
Entrez,  Source
fatty acid synthase13241-0.2880.0077No
Table: GSEA details [plain text format]



Fig 2: UVB_NHEK3_ALL   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: UVB_NHEK3_ALL: Random ES distribution   
Gene set null distribution of ES for UVB_NHEK3_ALL