Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | UVB_NHEK3_C0 |
| Enrichment Score (ES) | 0.6374257 |
| Normalized Enrichment Score (NES) | 2.1084063 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0019512966 |
| FWER p-Value | 0.027 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 10 | 0.815 | 0.1599 | Yes |
| 2 | ADM | ADM Entrez, Source | adrenomedullin | 34 | 0.649 | 0.2860 | Yes |
| 3 | IL1R2 | IL1R2 Entrez, Source | interleukin 1 receptor, type II | 46 | 0.599 | 0.4032 | Yes |
| 4 | GDF15 | GDF15 Entrez, Source | growth differentiation factor 15 | 58 | 0.559 | 0.5125 | Yes |
| 5 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 145 | 0.367 | 0.5783 | Yes |
| 6 | PRSS8 | PRSS8 Entrez, Source | protease, serine, 8 (prostasin) | 490 | 0.183 | 0.5885 | Yes |
| 7 | NEU1 | NEU1 Entrez, Source | sialidase 1 (lysosomal sialidase) | 510 | 0.181 | 0.6227 | Yes |
| 8 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 888 | 0.130 | 0.6200 | Yes |
| 9 | TPMT | TPMT Entrez, Source | thiopurine S-methyltransferase | 980 | 0.123 | 0.6374 | Yes |
| 10 | PTP4A1 | PTP4A1 Entrez, Source | protein tyrosine phosphatase type IVA, member 1 | 2184 | 0.068 | 0.5602 | No |
| 11 | GNAI1 | GNAI1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2424 | 0.061 | 0.5543 | No |
| 12 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 2512 | 0.059 | 0.5595 | No |
| 13 | ARL6IP1 | ARL6IP1 Entrez, Source | ADP-ribosylation factor-like 6 interacting protein 1 | 2527 | 0.059 | 0.5700 | No |
| 14 | DAZAP2 | DAZAP2 Entrez, Source | DAZ associated protein 2 | 3109 | 0.046 | 0.5354 | No |
| 15 | GTF2B | GTF2B Entrez, Source | general transcription factor IIB | 3140 | 0.046 | 0.5421 | No |
| 16 | MRPL49 | MRPL49 Entrez, Source | mitochondrial ribosomal protein L49 | 3463 | 0.039 | 0.5257 | No |
| 17 | GTF2A2 | GTF2A2 Entrez, Source | general transcription factor IIA, 2, 12kDa | 3615 | 0.037 | 0.5215 | No |
| 18 | KPNA2 | KPNA2 Entrez, Source | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 4109 | 0.029 | 0.4900 | No |
| 19 | PGRMC1 | PGRMC1 Entrez, Source | progesterone receptor membrane component 1 | 4136 | 0.028 | 0.4936 | No |
| 20 | PPP2CB | PPP2CB Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform | 4166 | 0.028 | 0.4969 | No |
| 21 | TAF9 | TAF9 Entrez, Source | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa | 4322 | 0.025 | 0.4901 | No |
| 22 | TRAM1 | TRAM1 Entrez, Source | translocation associated membrane protein 1 | 4581 | 0.021 | 0.4749 | No |
| 23 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 4639 | 0.020 | 0.4747 | No |
| 24 | EIF2B1 | EIF2B1 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | 5340 | 0.011 | 0.4240 | No |
| 25 | QSCN6 | QSCN6 Entrez, Source | quiescin Q6 | 5385 | 0.010 | 0.4227 | No |
| 26 | DR1 | DR1 Entrez, Source | down-regulator of transcription 1, TBP-binding (negative cofactor 2) | 5479 | 0.009 | 0.4174 | No |
| 27 | BPGM | BPGM Entrez, Source | 2,3-bisphosphoglycerate mutase | 5600 | 0.007 | 0.4097 | No |
| 28 | CDC37 | CDC37 Entrez, Source | CDC37 cell division cycle 37 homolog (S. cerevisiae) | 5747 | 0.005 | 0.3998 | No |
| 29 | COPS2 | COPS2 Entrez, Source | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 5856 | 0.004 | 0.3924 | No |
| 30 | BRD2 | BRD2 Entrez, Source | bromodomain containing 2 | 5876 | 0.004 | 0.3917 | No |
| 31 | PPIF | PPIF Entrez, Source | peptidylprolyl isomerase F (cyclophilin F) | 5913 | 0.003 | 0.3896 | No |
| 32 | DSC2 | DSC2 Entrez, Source | desmocollin 2 | 6067 | 0.001 | 0.3783 | No |
| 33 | HSPH1 | HSPH1 Entrez, Source | heat shock 105kDa/110kDa protein 1 | 6127 | 0.000 | 0.3739 | No |
| 34 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 6260 | -0.001 | 0.3643 | No |
| 35 | ATP6V0C | ATP6V0C Entrez, Source | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | 6333 | -0.002 | 0.3593 | No |
| 36 | PSMA4 | PSMA4 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 4 | 6523 | -0.005 | 0.3460 | No |
| 37 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 6696 | -0.007 | 0.3345 | No |
| 38 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 6700 | -0.007 | 0.3356 | No |
| 39 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 6771 | -0.008 | 0.3319 | No |
| 40 | TCEB1 | TCEB1 Entrez, Source | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 6931 | -0.010 | 0.3219 | No |
| 41 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 7062 | -0.011 | 0.3143 | No |
| 42 | SON | SON Entrez, Source | SON DNA binding protein | 7481 | -0.016 | 0.2861 | No |
| 43 | DNAJA1 | DNAJA1 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 1 | 7683 | -0.019 | 0.2748 | No |
| 44 | MCFD2 | MCFD2 Entrez, Source | multiple coagulation factor deficiency 2 | 7916 | -0.022 | 0.2617 | No |
| 45 | SAP18 | SAP18 Entrez, Source | Sin3A-associated protein, 18kDa | 7954 | -0.023 | 0.2634 | No |
| 46 | RRAGA | RRAGA Entrez, Source | Ras-related GTP binding A | 8100 | -0.025 | 0.2574 | No |
| 47 | USP10 | USP10 Entrez, Source | ubiquitin specific peptidase 10 | 8103 | -0.025 | 0.2622 | No |
| 48 | EIF2S1 | EIF2S1 Entrez, Source | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 8354 | -0.029 | 0.2490 | No |
| 49 | PSMD6 | PSMD6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 8376 | -0.029 | 0.2531 | No |
| 50 | CTR9 | CTR9 Entrez, Source | Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 8385 | -0.029 | 0.2582 | No |
| 51 | EIF4G2 | EIF4G2 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 2 | 8447 | -0.030 | 0.2595 | No |
| 52 | GSK3A | GSK3A Entrez, Source | glycogen synthase kinase 3 alpha | 8514 | -0.031 | 0.2607 | No |
| 53 | BAMBI | BAMBI Entrez, Source | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) | 8540 | -0.031 | 0.2649 | No |
| 54 | CLTA | CLTA Entrez, Source | clathrin, light chain (Lca) | 9172 | -0.040 | 0.2253 | No |
| 55 | SLC39A6 | SLC39A6 Entrez, Source | solute carrier family 39 (zinc transporter), member 6 | 9664 | -0.048 | 0.1978 | No |
| 56 | IL1RN | IL1RN Entrez, Source | interleukin 1 receptor antagonist | 10196 | -0.057 | 0.1690 | No |
| 57 | UBE2V2 | UBE2V2 Entrez, Source | ubiquitin-conjugating enzyme E2 variant 2 | 10326 | -0.059 | 0.1709 | No |
| 58 | RPS24 | RPS24 Entrez, Source | ribosomal protein S24 | 11160 | -0.077 | 0.1234 | No |
| 59 | RAB21 | RAB21 Entrez, Source | RAB21, member RAS oncogene family | 11632 | -0.090 | 0.1056 | No |
| 60 | HMOX1 | HMOX1 Entrez, Source | heme oxygenase (decycling) 1 | 12319 | -0.117 | 0.0770 | No |
