Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | UVB_NHEK3_C1 |
| Enrichment Score (ES) | 0.56238174 |
| Normalized Enrichment Score (NES) | 1.7752551 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.03571106 |
| FWER p-Value | 0.993 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 32 | 0.660 | 0.1743 | Yes |
| 2 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 44 | 0.606 | 0.3358 | Yes |
| 3 | CRYAB | CRYAB Entrez, Source | crystallin, alpha B | 141 | 0.371 | 0.4280 | Yes |
| 4 | SLC31A2 | SLC31A2 Entrez, Source | solute carrier family 31 (copper transporters), member 2 | 268 | 0.267 | 0.4899 | Yes |
| 5 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 553 | 0.172 | 0.5146 | Yes |
| 6 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 559 | 0.171 | 0.5600 | Yes |
| 7 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 1177 | 0.111 | 0.5432 | Yes |
| 8 | IER2 | IER2 Entrez, Source | immediate early response 2 | 1295 | 0.104 | 0.5624 | Yes |
| 9 | CST6 | CST6 Entrez, Source | cystatin E/M | 2108 | 0.069 | 0.5199 | No |
| 10 | PSMA6 | PSMA6 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 6 | 2734 | 0.054 | 0.4874 | No |
| 11 | RNF4 | RNF4 Entrez, Source | ring finger protein 4 | 3580 | 0.037 | 0.4338 | No |
| 12 | MAP2K3 | MAP2K3 Entrez, Source | mitogen-activated protein kinase kinase 3 | 4321 | 0.025 | 0.3849 | No |
| 13 | HSP90AA1 | HSP90AA1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 4655 | 0.020 | 0.3653 | No |
| 14 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 4788 | 0.018 | 0.3603 | No |
| 15 | LCN2 | LCN2 Entrez, Source | lipocalin 2 (oncogene 24p3) | 4934 | 0.016 | 0.3537 | No |
| 16 | PPP2R2A | PPP2R2A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform | 4968 | 0.016 | 0.3554 | No |
| 17 | WBSCR1 | WBSCR1 Entrez, Source | Williams-Beuren syndrome chromosome region 1 | 5863 | 0.004 | 0.2892 | No |
| 18 | CSNK2A1 | CSNK2A1 Entrez, Source | casein kinase 2, alpha 1 polypeptide | 5898 | 0.003 | 0.2876 | No |
| 19 | UBE2G1 | UBE2G1 Entrez, Source | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) | 6486 | -0.004 | 0.2445 | No |
| 20 | PSMC2 | PSMC2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 6594 | -0.006 | 0.2380 | No |
| 21 | GPIAP1 | GPIAP1 Entrez, Source | GPI-anchored membrane protein 1 | 6728 | -0.007 | 0.2300 | No |
| 22 | GALNT3 | GALNT3 Entrez, Source | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) | 6927 | -0.010 | 0.2177 | No |
| 23 | TJP2 | TJP2 Entrez, Source | tight junction protein 2 (zona occludens 2) | 7094 | -0.012 | 0.2084 | No |
| 24 | COPS8 | COPS8 Entrez, Source | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 7463 | -0.016 | 0.1851 | No |
| 25 | VDAC2 | VDAC2 Entrez, Source | voltage-dependent anion channel 2 | 7498 | -0.017 | 0.1870 | No |
| 26 | SAFB | SAFB Entrez, Source | scaffold attachment factor B | 7539 | -0.017 | 0.1886 | No |
| 27 | KCNK1 | KCNK1 Entrez, Source | potassium channel, subfamily K, member 1 | 7542 | -0.017 | 0.1930 | No |
| 28 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 7976 | -0.023 | 0.1667 | No |
| 29 | UBE2I | UBE2I Entrez, Source | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 8006 | -0.024 | 0.1708 | No |
| 30 | TSG101 | TSG101 Entrez, Source | tumor susceptibility gene 101 | 8034 | -0.024 | 0.1752 | No |
| 31 | MAPK6 | MAPK6 Entrez, Source | mitogen-activated protein kinase 6 | 8081 | -0.025 | 0.1784 | No |
| 32 | PSMC1 | PSMC1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 8118 | -0.025 | 0.1824 | No |
| 33 | PSMC6 | PSMC6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 8252 | -0.027 | 0.1797 | No |
| 34 | GPX2 | GPX2 Entrez, Source | glutathione peroxidase 2 (gastrointestinal) | 8829 | -0.035 | 0.1458 | No |
| 35 | CNN3 | CNN3 Entrez, Source | calponin 3, acidic | 8886 | -0.036 | 0.1512 | No |
| 36 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 8969 | -0.037 | 0.1550 | No |
| 37 | PSMA5 | PSMA5 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 5 | 9533 | -0.046 | 0.1249 | No |
| 38 | UBXD2 | UBXD2 Entrez, Source | UBX domain containing 2 | 9639 | -0.048 | 0.1298 | No |
| 39 | PBEF1 | PBEF1 Entrez, Source | pre-B-cell colony enhancing factor 1 | 10279 | -0.058 | 0.0973 | No |
| 40 | GLUL | GLUL Entrez, Source | glutamate-ammonia ligase (glutamine synthetase) | 10574 | -0.064 | 0.0922 | No |
| 41 | ATP6V1B2 | ATP6V1B2 Entrez, Source | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | 10631 | -0.065 | 0.1054 | No |
| 42 | UBE2D2 | UBE2D2 Entrez, Source | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | 10785 | -0.068 | 0.1121 | No |
| 43 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 11624 | -0.090 | 0.0731 | No |
| 44 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 11880 | -0.098 | 0.0803 | No |
| 45 | ETF1 | ETF1 Entrez, Source | eukaryotic translation termination factor 1 | 12179 | -0.110 | 0.0875 | No |
