Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | UVB_NHEK3_C8 |
| Enrichment Score (ES) | 0.5982938 |
| Normalized Enrichment Score (NES) | 1.8415575 |
| Nominal p-value | 0.0016638935 |
| FDR q-value | 0.024925798 |
| FWER p-Value | 0.878 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 11 | 0.815 | 0.1473 | Yes |
| 2 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 28 | 0.668 | 0.2674 | Yes |
| 3 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 52 | 0.576 | 0.3703 | Yes |
| 4 | PTPRZ1 | PTPRZ1 Entrez, Source | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 65 | 0.523 | 0.4644 | Yes |
| 5 | HK1 | HK1 Entrez, Source | hexokinase 1 | 197 | 0.323 | 0.5133 | Yes |
| 6 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 372 | 0.219 | 0.5400 | Yes |
| 7 | SCRN1 | SCRN1 Entrez, Source | secernin 1 | 568 | 0.170 | 0.5563 | Yes |
| 8 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 646 | 0.158 | 0.5792 | Yes |
| 9 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 744 | 0.145 | 0.5983 | Yes |
| 10 | SLC2A1 | SLC2A1 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 1 | 1212 | 0.109 | 0.5830 | No |
| 11 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 2181 | 0.068 | 0.5225 | No |
| 12 | PON2 | PON2 Entrez, Source | paraoxonase 2 | 2308 | 0.064 | 0.5247 | No |
| 13 | GLG1 | GLG1 Entrez, Source | golgi apparatus protein 1 | 2729 | 0.054 | 0.5030 | No |
| 14 | R3HDM1 | R3HDM1 Entrez, Source | R3H domain containing 1 | 2857 | 0.052 | 0.5028 | No |
| 15 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 3298 | 0.043 | 0.4774 | No |
| 16 | PRDX6 | PRDX6 Entrez, Source | peroxiredoxin 6 | 4430 | 0.023 | 0.3966 | No |
| 17 | TOMM20 | TOMM20 Entrez, Source | translocase of outer mitochondrial membrane 20 homolog (yeast) | 4757 | 0.019 | 0.3756 | No |
| 18 | ST6GALNAC2 | ST6GALNAC2 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 4765 | 0.019 | 0.3784 | No |
| 19 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 5266 | 0.012 | 0.3429 | No |
| 20 | PFN2 | PFN2 Entrez, Source | profilin 2 | 5738 | 0.005 | 0.3085 | No |
| 21 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 6404 | -0.003 | 0.2590 | No |
| 22 | TMED10 | TMED10 Entrez, Source | transmembrane emp24-like trafficking protein 10 (yeast) | 6770 | -0.008 | 0.2330 | No |
| 23 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 7060 | -0.011 | 0.2134 | No |
| 24 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 7318 | -0.014 | 0.1967 | No |
| 25 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 7715 | -0.020 | 0.1704 | No |
| 26 | ATP5O | ATP5O Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 7722 | -0.020 | 0.1736 | No |
| 27 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 7752 | -0.020 | 0.1750 | No |
| 28 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7792 | -0.021 | 0.1758 | No |
| 29 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 8238 | -0.027 | 0.1473 | No |
| 30 | FLNB | FLNB Entrez, Source | filamin B, beta (actin binding protein 278) | 8603 | -0.032 | 0.1258 | No |
| 31 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 9270 | -0.041 | 0.0832 | No |
| 32 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 9332 | -0.042 | 0.0863 | No |
| 33 | PTPRF | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 9495 | -0.045 | 0.0822 | No |
| 34 | PTPRK | PTPRK Entrez, Source | protein tyrosine phosphatase, receptor type, K | 9501 | -0.045 | 0.0901 | No |
| 35 | PGM1 | PGM1 Entrez, Source | phosphoglucomutase 1 | 10277 | -0.058 | 0.0423 | No |
| 36 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 10414 | -0.060 | 0.0431 | No |
| 37 | FBN2 | FBN2 Entrez, Source | fibrillin 2 (congenital contractural arachnodactyly) | 10607 | -0.064 | 0.0404 | No |
| 38 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 10686 | -0.066 | 0.0465 | No |
| 39 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 10889 | -0.071 | 0.0441 | No |
| 40 | FDFT1 | FDFT1 Entrez, Source | farnesyl-diphosphate farnesyltransferase 1 | 11716 | -0.093 | -0.0012 | No |
| 41 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 12268 | -0.115 | -0.0218 | No |
| 42 | GJB2 | GJB2 Entrez, Source | gap junction protein, beta 2, 26kDa (connexin 26) | 12323 | -0.117 | -0.0046 | No |
| 43 | FGFR3 | FGFR3 Entrez, Source | fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) | 12848 | -0.158 | -0.0152 | No |
| 44 | FASN | FASN Entrez, Source | fatty acid synthase | 13241 | -0.288 | 0.0076 | No |
