Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | UVC_TTD_8HR_DN |
| Enrichment Score (ES) | 0.5246725 |
| Normalized Enrichment Score (NES) | 1.819121 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.029427463 |
| FWER p-Value | 0.945 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 12 | 0.803 | 0.0925 | Yes |
| 2 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 28 | 0.668 | 0.1692 | Yes |
| 3 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 32 | 0.660 | 0.2457 | Yes |
| 4 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 222 | 0.305 | 0.2669 | Yes |
| 5 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 280 | 0.261 | 0.2930 | Yes |
| 6 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 418 | 0.205 | 0.3065 | Yes |
| 7 | MGLL | MGLL Entrez, Source | monoglyceride lipase | 454 | 0.195 | 0.3265 | Yes |
| 8 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 496 | 0.183 | 0.3447 | Yes |
| 9 | GPR176 | GPR176 Entrez, Source | G protein-coupled receptor 176 | 502 | 0.182 | 0.3654 | Yes |
| 10 | CUTL1 | CUTL1 Entrez, Source | cut-like 1, CCAAT displacement protein (Drosophila) | 516 | 0.180 | 0.3854 | Yes |
| 11 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 561 | 0.171 | 0.4019 | Yes |
| 12 | XRCC4 | XRCC4 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 4 | 586 | 0.167 | 0.4196 | Yes |
| 13 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 633 | 0.160 | 0.4347 | Yes |
| 14 | IFRD1 | IFRD1 Entrez, Source | interferon-related developmental regulator 1 | 841 | 0.135 | 0.4348 | Yes |
| 15 | CBLB | CBLB Entrez, Source | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 858 | 0.133 | 0.4491 | Yes |
| 16 | STK39 | STK39 Entrez, Source | serine threonine kinase 39 (STE20/SPS1 homolog, yeast) | 864 | 0.133 | 0.4642 | Yes |
| 17 | ENC1 | ENC1 Entrez, Source | ectodermal-neural cortex (with BTB-like domain) | 1029 | 0.119 | 0.4656 | Yes |
| 18 | RGS7 | RGS7 Entrez, Source | regulator of G-protein signalling 7 | 1078 | 0.116 | 0.4755 | Yes |
| 19 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1297 | 0.104 | 0.4712 | Yes |
| 20 | MYO1B | MYO1B Entrez, Source | myosin IB | 1311 | 0.104 | 0.4823 | Yes |
| 21 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 1323 | 0.103 | 0.4935 | Yes |
| 22 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 1434 | 0.097 | 0.4964 | Yes |
| 23 | EDG2 | EDG2 Entrez, Source | endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 | 1468 | 0.095 | 0.5050 | Yes |
| 24 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 1606 | 0.089 | 0.5050 | Yes |
| 25 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 1672 | 0.086 | 0.5101 | Yes |
| 26 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 1731 | 0.083 | 0.5155 | Yes |
| 27 | FARS2 | FARS2 Entrez, Source | phenylalanine-tRNA synthetase 2 (mitochondrial) | 1738 | 0.083 | 0.5247 | Yes |
| 28 | NRG1 | NRG1 Entrez, Source | neuregulin 1 | 1967 | 0.074 | 0.5161 | No |
| 29 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 2118 | 0.069 | 0.5128 | No |
| 30 | ATXN1 | ATXN1 Entrez, Source | ataxin 1 | 2254 | 0.066 | 0.5103 | No |
| 31 | FUT8 | FUT8 Entrez, Source | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 2270 | 0.065 | 0.5168 | No |
| 32 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 2366 | 0.063 | 0.5169 | No |
| 33 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 2479 | 0.060 | 0.5155 | No |
| 34 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 2895 | 0.051 | 0.4901 | No |
| 35 | TDRD3 | TDRD3 Entrez, Source | tudor domain containing 3 | 2985 | 0.049 | 0.4891 | No |
| 36 | NFIB | NFIB Entrez, Source | nuclear factor I/B | 3057 | 0.047 | 0.4893 | No |
| 37 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 3267 | 0.043 | 0.4785 | No |
| 38 | ZMYND11 | ZMYND11 Entrez, Source | zinc finger, MYND domain containing 11 | 3412 | 0.040 | 0.4724 | No |
| 39 | TRIO | TRIO Entrez, Source | triple functional domain (PTPRF interacting) | 3491 | 0.039 | 0.4710 | No |
| 40 | UBL3 | UBL3 Entrez, Source | ubiquitin-like 3 | 3509 | 0.038 | 0.4742 | No |
| 41 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 3538 | 0.038 | 0.4765 | No |
| 42 | TSPAN5 | TSPAN5 Entrez, Source | tetraspanin 5 | 4392 | 0.024 | 0.4149 | No |
| 43 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 4556 | 0.022 | 0.4052 | No |
| 44 | WDR7 | WDR7 Entrez, Source | WD repeat domain 7 | 4599 | 0.021 | 0.4045 | No |
| 45 | ATP2B1 | ATP2B1 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 1 | 5288 | 0.011 | 0.3539 | No |
| 46 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 5296 | 0.011 | 0.3547 | No |
| 47 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 5527 | 0.008 | 0.3382 | No |
| 48 | AMPH | AMPH Entrez, Source | amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen) | 5916 | 0.003 | 0.3094 | No |
| 49 | CAP2 | CAP2 Entrez, Source | CAP, adenylate cyclase-associated protein, 2 (yeast) | 6076 | 0.001 | 0.2975 | No |
| 50 | SEPT9 | SEPT9 Entrez, Source | septin 9 | 6782 | -0.008 | 0.2453 | No |
| 51 | BMP2K | BMP2K Entrez, Source | BMP2 inducible kinase | 6985 | -0.011 | 0.2313 | No |
| 52 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 7715 | -0.020 | 0.1786 | No |
| 53 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 7752 | -0.020 | 0.1782 | No |
| 54 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 7943 | -0.023 | 0.1665 | No |
| 55 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 8090 | -0.025 | 0.1584 | No |
| 56 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 8235 | -0.027 | 0.1507 | No |
| 57 | AFAP | AFAP Entrez, Source | - | 8284 | -0.028 | 0.1502 | No |
| 58 | SERPINB2 | SERPINB2 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 8340 | -0.028 | 0.1494 | No |
| 59 | PDLIM5 | PDLIM5 Entrez, Source | PDZ and LIM domain 5 | 8373 | -0.029 | 0.1503 | No |
| 60 | CDC42BPA | CDC42BPA Entrez, Source | CDC42 binding protein kinase alpha (DMPK-like) | 8396 | -0.029 | 0.1521 | No |
| 61 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 8524 | -0.031 | 0.1461 | No |
| 62 | FLNB | FLNB Entrez, Source | filamin B, beta (actin binding protein 278) | 8603 | -0.032 | 0.1440 | No |
| 63 | SLC4A7 | SLC4A7 Entrez, Source | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 8929 | -0.037 | 0.1238 | No |
| 64 | FGF5 | FGF5 Entrez, Source | fibroblast growth factor 5 | 9130 | -0.039 | 0.1132 | No |
| 65 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 9243 | -0.041 | 0.1095 | No |
| 66 | PKN2 | PKN2 Entrez, Source | protein kinase N2 | 9361 | -0.043 | 0.1057 | No |
| 67 | PTPRK | PTPRK Entrez, Source | protein tyrosine phosphatase, receptor type, K | 9501 | -0.045 | 0.1005 | No |
| 68 | GBE1 | GBE1 Entrez, Source | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 10501 | -0.062 | 0.0324 | No |
| 69 | PTPRM | PTPRM Entrez, Source | protein tyrosine phosphatase, receptor type, M | 10978 | -0.073 | 0.0049 | No |
| 70 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 10979 | -0.073 | 0.0134 | No |
| 71 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 11134 | -0.077 | 0.0107 | No |
| 72 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 11286 | -0.081 | 0.0087 | No |
| 73 | MDN1 | MDN1 Entrez, Source | MDN1, midasin homolog (yeast) | 12007 | -0.103 | -0.0335 | No |
| 74 | PARD3 | PARD3 Entrez, Source | par-3 partitioning defective 3 homolog (C. elegans) | 12232 | -0.113 | -0.0373 | No |
| 75 | CASK | CASK Entrez, Source | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 12276 | -0.115 | -0.0272 | No |
| 76 | CLASP2 | CLASP2 Entrez, Source | cytoplasmic linker associated protein 2 | 12307 | -0.116 | -0.0159 | No |
| 77 | GTF2F2 | GTF2F2 Entrez, Source | general transcription factor IIF, polypeptide 2, 30kDa | 12398 | -0.121 | -0.0086 | No |
| 78 | SKAP2 | SKAP2 Entrez, Source | src kinase associated phosphoprotein 2 | 12646 | -0.138 | -0.0112 | No |
| 79 | TCF12 | TCF12 Entrez, Source | transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) | 12682 | -0.140 | 0.0025 | No |
| 80 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 12892 | -0.163 | 0.0057 | No |
| 81 | GULP1 | GULP1 Entrez, Source | GULP, engulfment adaptor PTB domain containing 1 | 13181 | -0.242 | 0.0121 | No |
