Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | V$AHRARNT_01 |
| Enrichment Score (ES) | 0.5093939 |
| Normalized Enrichment Score (NES) | 1.744213 |
| Nominal p-value | 0.0034188034 |
| FDR q-value | 0.04283588 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BHLHB3 | BHLHB3 Entrez, Source | basic helix-loop-helix domain containing, class B, 3 | 23 | 0.682 | 0.0977 | Yes |
| 2 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 32 | 0.660 | 0.1934 | Yes |
| 3 | TACC1 | TACC1 Entrez, Source | transforming, acidic coiled-coil containing protein 1 | 53 | 0.575 | 0.2758 | Yes |
| 4 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 57 | 0.561 | 0.3574 | Yes |
| 5 | JAG1 | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 323 | 0.239 | 0.3723 | Yes |
| 6 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 330 | 0.237 | 0.4064 | Yes |
| 7 | CRH | CRH Entrez, Source | corticotropin releasing hormone | 541 | 0.173 | 0.4158 | Yes |
| 8 | GRM7 | GRM7 Entrez, Source | glutamate receptor, metabotropic 7 | 672 | 0.154 | 0.4286 | Yes |
| 9 | CNTNAP1 | CNTNAP1 Entrez, Source | contactin associated protein 1 | 673 | 0.154 | 0.4511 | Yes |
| 10 | IHPK2 | IHPK2 Entrez, Source | inositol hexaphosphate kinase 2 | 835 | 0.136 | 0.4588 | Yes |
| 11 | KLF15 | KLF15 Entrez, Source | Kruppel-like factor 15 | 1016 | 0.121 | 0.4628 | Yes |
| 12 | WSB1 | WSB1 Entrez, Source | WD repeat and SOCS box-containing 1 | 1023 | 0.119 | 0.4797 | Yes |
| 13 | JUB | JUB Entrez, Source | jub, ajuba homolog (Xenopus laevis) | 1150 | 0.112 | 0.4866 | Yes |
| 14 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 1192 | 0.110 | 0.4995 | Yes |
| 15 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 1267 | 0.106 | 0.5094 | Yes |
| 16 | REPIN1 | REPIN1 Entrez, Source | replication initiator 1 | 1999 | 0.073 | 0.4650 | No |
| 17 | PTF1A | PTF1A Entrez, Source | pancreas specific transcription factor, 1a | 2008 | 0.073 | 0.4750 | No |
| 18 | STC2 | STC2 Entrez, Source | stanniocalcin 2 | 2009 | 0.073 | 0.4856 | No |
| 19 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 2079 | 0.071 | 0.4907 | No |
| 20 | BCL11A | BCL11A Entrez, Source | B-cell CLL/lymphoma 11A (zinc finger protein) | 2222 | 0.067 | 0.4898 | No |
| 21 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 2278 | 0.065 | 0.4951 | No |
| 22 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 2881 | 0.051 | 0.4572 | No |
| 23 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 3793 | 0.034 | 0.3935 | No |
| 24 | ZFHX1B | ZFHX1B Entrez, Source | zinc finger homeobox 1b | 3802 | 0.033 | 0.3978 | No |
| 25 | RGS8 | RGS8 Entrez, Source | regulator of G-protein signalling 8 | 4068 | 0.029 | 0.3821 | No |
| 26 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 4101 | 0.029 | 0.3838 | No |
| 27 | SEZ6 | SEZ6 Entrez, Source | seizure related 6 homolog (mouse) | 4170 | 0.028 | 0.3827 | No |
| 28 | NLGN3 | NLGN3 Entrez, Source | neuroligin 3 | 4303 | 0.025 | 0.3765 | No |
| 29 | HPCAL1 | HPCAL1 Entrez, Source | hippocalcin-like 1 | 4353 | 0.025 | 0.3764 | No |
| 30 | GNAO1 | GNAO1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 4514 | 0.022 | 0.3676 | No |
| 31 | CAMK2D | CAMK2D Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II delta | 4524 | 0.022 | 0.3701 | No |
| 32 | KAZALD1 | KAZALD1 Entrez, Source | Kazal-type serine peptidase inhibitor domain 1 | 4583 | 0.021 | 0.3689 | No |
| 33 | EIF4A2 | EIF4A2 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 2 | 4806 | 0.018 | 0.3548 | No |
| 34 | CYP26B1 | CYP26B1 Entrez, Source | cytochrome P450, family 26, subfamily B, polypeptide 1 | 4879 | 0.017 | 0.3519 | No |
| 35 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 4916 | 0.016 | 0.3515 | No |
| 36 | PHF1 | PHF1 Entrez, Source | PHD finger protein 1 | 5282 | 0.011 | 0.3257 | No |
| 37 | ID4 | ID4 Entrez, Source | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 5661 | 0.006 | 0.2981 | No |
| 38 | MAEA | MAEA Entrez, Source | macrophage erythroblast attacher | 5897 | 0.003 | 0.2809 | No |
| 39 | LHX1 | LHX1 Entrez, Source | LIM homeobox 1 | 6116 | 0.000 | 0.2646 | No |
| 40 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 6398 | -0.003 | 0.2438 | No |
| 41 | TAF11 | TAF11 Entrez, Source | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa | 6619 | -0.006 | 0.2281 | No |
| 42 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 6663 | -0.007 | 0.2259 | No |
| 43 | NEUROD2 | NEUROD2 Entrez, Source | neurogenic differentiation 2 | 6765 | -0.008 | 0.2194 | No |
| 44 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 7262 | -0.014 | 0.1840 | No |
| 45 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 7269 | -0.014 | 0.1856 | No |
| 46 | GABRA1 | GABRA1 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 7416 | -0.016 | 0.1769 | No |
| 47 | ACSL4 | ACSL4 Entrez, Source | acyl-CoA synthetase long-chain family member 4 | 7452 | -0.016 | 0.1766 | No |
| 48 | RGS6 | RGS6 Entrez, Source | regulator of G-protein signalling 6 | 7652 | -0.019 | 0.1643 | No |
| 49 | WNT4 | WNT4 Entrez, Source | wingless-type MMTV integration site family, member 4 | 7687 | -0.019 | 0.1646 | No |
| 50 | HK2 | HK2 Entrez, Source | hexokinase 2 | 7823 | -0.021 | 0.1575 | No |
| 51 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 8090 | -0.025 | 0.1411 | No |
| 52 | PPM2C | PPM2C Entrez, Source | protein phosphatase 2C, magnesium-dependent, catalytic subunit | 8778 | -0.035 | 0.0944 | No |
| 53 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 8836 | -0.035 | 0.0952 | No |
| 54 | IL7 | IL7 Entrez, Source | interleukin 7 | 8864 | -0.036 | 0.0984 | No |
| 55 | TNPO3 | TNPO3 Entrez, Source | transportin 3 | 9186 | -0.040 | 0.0801 | No |
| 56 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 9565 | -0.046 | 0.0583 | No |
| 57 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 10990 | -0.073 | -0.0383 | No |
| 58 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 11134 | -0.077 | -0.0379 | No |
| 59 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 11271 | -0.081 | -0.0364 | No |
| 60 | VDP | VDP Entrez, Source | - | 11959 | -0.101 | -0.0734 | No |
| 61 | GTF2A1 | GTF2A1 Entrez, Source | general transcription factor IIA, 1, 19/37kDa | 12080 | -0.106 | -0.0669 | No |
| 62 | MAGED2 | MAGED2 Entrez, Source | melanoma antigen family D, 2 | 12317 | -0.117 | -0.0676 | No |
| 63 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 12440 | -0.123 | -0.0589 | No |
| 64 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 12463 | -0.125 | -0.0423 | No |
| 65 | ABTB2 | ABTB2 Entrez, Source | ankyrin repeat and BTB (POZ) domain containing 2 | 12516 | -0.129 | -0.0273 | No |
| 66 | SYT12 | SYT12 Entrez, Source | synaptotagmin XII | 12566 | -0.133 | -0.0117 | No |
| 67 | XPO6 | XPO6 Entrez, Source | exportin 6 | 12613 | -0.135 | 0.0046 | No |
| 68 | GHR | GHR Entrez, Source | growth hormone receptor | 12744 | -0.146 | 0.0161 | No |
| 69 | TRIM23 | TRIM23 Entrez, Source | tripartite motif-containing 23 | 13053 | -0.198 | 0.0218 | No |
