Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_8d
GeneSetV$AP1_C
Enrichment Score (ES)0.47291303
Normalized Enrichment Score (NES)1.776668
Nominal p-value0.0
FDR q-value0.035803013
FWER p-Value0.993
Table: GSEA Results Summary



Fig 1: Enrichment plot: V$AP1_C   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1LAMC2LAMC2
Entrez,  Source
laminin, gamma 2140.7700.0654Yes
2PROCRPROCR
Entrez,  Source
protein C receptor, endothelial (EPCR)260.6690.1223Yes
3RGS2RGS2
Entrez,  Source
regulator of G-protein signalling 2, 24kDa420.6160.1743Yes
4EMP1EMP1
Entrez,  Source
epithelial membrane protein 1440.6060.2266Yes
5FSTL1FSTL1
Entrez,  Source
follistatin-like 1800.4690.2644Yes
6MYBPHMYBPH
Entrez,  Source
myosin binding protein H1240.3960.2953Yes
7HS3ST2HS3ST2
Entrez,  Source
heparan sulfate (glucosamine) 3-O-sulfotransferase 21290.3910.3287Yes
8GJA1GJA1
Entrez,  Source
gap junction protein, alpha 1, 43kDa (connexin 43)1960.3240.3517Yes
9LAMC1LAMC1
Entrez,  Source
laminin, gamma 1 (formerly LAMB2)2240.3030.3758Yes
10PEA15PEA15
Entrez,  Source
phosphoprotein enriched in astrocytes 152520.2810.3980Yes
11CLIC1CLIC1
Entrez,  Source
chloride intracellular channel 14630.1920.3987Yes
12RBP4RBP4
Entrez,  Source
retinol binding protein 4, plasma5540.1720.4067Yes
13FABP4FABP4
Entrez,  Source
fatty acid binding protein 4, adipocyte6380.1590.4141Yes
14RHBDF1RHBDF1
Entrez,  Source
rhomboid 5 homolog 1 (Drosophila)6610.1560.4260Yes
15CSF3CSF3
Entrez,  Source
colony stimulating factor 3 (granulocyte)6850.1520.4373Yes
16USP2USP2
Entrez,  Source
ubiquitin specific peptidase 26940.1510.4497Yes
17PPP2CAPPP2CA
Entrez,  Source
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform8020.1390.4537Yes
18FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)9210.1270.4557Yes
19HSPB6HSPB6
Entrez,  Source
heat shock protein, alpha-crystallin-related, B611060.1140.4517Yes
20NEFHNEFH
Entrez,  Source
neurofilament, heavy polypeptide 200kDa11470.1120.4583Yes
21CMASCMAS
Entrez,  Source
cytidine monophosphate N-acetylneuraminic acid synthetase12180.1090.4624Yes
22SV2BSV2B
Entrez,  Source
synaptic vesicle glycoprotein 2B12810.1050.4668Yes
23IL10IL10
Entrez,  Source
interleukin 1013290.1020.4721Yes
24ROM1ROM1
Entrez,  Source
retinal outer segment membrane protein 114290.0970.4729Yes
25SERPINB5SERPINB5
Entrez,  Source
serpin peptidase inhibitor, clade B (ovalbumin), member 516610.0860.4629No
26ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 217310.0830.4648No
27SLC16A6SLC16A6
Entrez,  Source
solute carrier family 16, member 6 (monocarboxylic acid transporter 7)17750.0810.4686No
28PLCD1PLCD1
Entrez,  Source
phospholipase C, delta 118990.0770.4659No
29FGF11FGF11
Entrez,  Source
fibroblast growth factor 1126950.0550.4105No
30RIN1RIN1
Entrez,  Source
Ras and Rab interactor 127780.0530.4089No
31ITPKCITPKC
Entrez,  Source
inositol 1,4,5-trisphosphate 3-kinase C28070.0530.4113No
32PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide28710.0510.4110No
33XYLT1XYLT1
Entrez,  Source
xylosyltransferase I30250.0480.4036No
34CLSTN3CLSTN3
Entrez,  Source
calsyntenin 330510.0470.4058No
35LTBP3LTBP3
Entrez,  Source
latent transforming growth factor beta binding protein 332170.0440.3971No
36ATP6V1C2ATP6V1C2
Entrez,  Source
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C233160.0420.3933No
37GDNFGDNF
Entrez,  Source
glial cell derived neurotrophic factor34130.0400.3895No
38SFTPCSFTPC
Entrez,  Source
surfactant, pulmonary-associated protein C35120.0380.3854No
39PPP1R9BPPP1R9B
Entrez,  Source
protein phosphatase 1, regulatory subunit 9B, spinophilin37260.0350.3723No
40RBBP7RBBP7
Entrez,  Source
retinoblastoma binding protein 737930.0340.3702No
41SNX10SNX10
Entrez,  Source
sorting nexin 1039450.0310.3615No
42PSMD1PSMD1
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 140430.0300.3567No
43ADAM15ADAM15
Entrez,  Source
ADAM metallopeptidase domain 15 (metargidin)40450.0300.3591No
44SDCBPSDCBP
Entrez,  Source
syndecan binding protein (syntenin)40640.0290.3603No
45PPP2CBPPP2CB
Entrez,  Source
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform41660.0280.3550No
46MAPRE3MAPRE3
Entrez,  Source
microtubule-associated protein, RP/EB family, member 341810.0270.3564No
47BTG3BTG3
Entrez,  Source
BTG family, member 343870.0240.3429No
48SNCGSNCG
Entrez,  Source
synuclein, gamma (breast cancer-specific protein 1)44820.0230.3377No
49HSPB7HSPB7
Entrez,  Source
heat shock 27kDa protein family, member 7 (cardiovascular)45570.0220.3340No
50BLR1BLR1
Entrez,  Source
Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)47640.0190.3200No
51CNTFCNTF
Entrez,  Source
ciliary neurotrophic factor47820.0180.3203No
52ATP1B1ATP1B1
Entrez,  Source
ATPase, Na+/K+ transporting, beta 1 polypeptide47880.0180.3216No
53DSCR1L1DSCR1L1
Entrez,  Source
Down syndrome critical region gene 1-like 148000.0180.3223No
54FIGFFIGF
Entrez,  Source
c-fos induced growth factor (vascular endothelial growth factor D)48550.0170.3197No
55COL16A1COL16A1
Entrez,  Source
collagen, type XVI, alpha 150510.0150.3062No
56TRAPPC3TRAPPC3
Entrez,  Source
trafficking protein particle complex 351820.0130.2975No
57IVLIVL
Entrez,  Source
involucrin53420.0110.2864No
58ESRRGESRRG
Entrez,  Source
estrogen-related receptor gamma53780.0100.2846No
59CAPN6CAPN6
Entrez,  Source
calpain 654800.0090.2777No
60LENEPLENEP
Entrez,  Source
lens epithelial protein55640.0070.2720No
61MAP1AMAP1A
Entrez,  Source
microtubule-associated protein 1A57150.0050.2612No
62GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha57880.0050.2561No
63LMNALMNA
Entrez,  Source
lamin A/C58050.0040.2553No
64RNF34RNF34
Entrez,  Source
ring finger protein 3460090.0020.2401No
65KCNH6KCNH6
Entrez,  Source
potassium voltage-gated channel, subfamily H (eag-related), member 660200.0020.2395No
66FBXO2FBXO2
Entrez,  Source
F-box protein 260300.0020.2390No
67AQP5AQP5
Entrez,  Source
aquaporin 560380.0020.2386No
68PTPRRPTPRR
Entrez,  Source
protein tyrosine phosphatase, receptor type, R61020.0010.2339No
69FLNCFLNC
Entrez,  Source
filamin C, gamma (actin binding protein 280)6220-0.0010.2251No
70RELARELA
Entrez,  Source
v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)6260-0.0010.2223No
71LAMA3LAMA3
Entrez,  Source
laminin, alpha 36404-0.0030.2117No
72NOTCH4NOTCH4
Entrez,  Source
Notch homolog 4 (Drosophila)6512-0.0050.2040No
73OMGOMG
Entrez,  Source
oligodendrocyte myelin glycoprotein6563-0.0050.2007No
74RAB3DRAB3D
Entrez,  Source
RAB3D, member RAS oncogene family6624-0.0060.1967No
75RTN3RTN3
Entrez,  Source
reticulon 36650-0.0060.1953No
76VAPAVAPA
Entrez,  Source
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa6685-0.0070.1934No
77SYTL1SYTL1
Entrez,  Source
synaptotagmin-like 16803-0.0080.1852No
78ADCK4ADCK4
Entrez,  Source
aarF domain containing kinase 46862-0.0090.1816No
79SLC35B1SLC35B1
Entrez,  Source
solute carrier family 35, member B16890-0.0090.1803No
80SMARCA2SMARCA2
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 26971-0.0100.1752No
81HDAC3HDAC3
Entrez,  Source
histone deacetylase 37165-0.0130.1617No
82BLMHBLMH
Entrez,  Source
bleomycin hydrolase7183-0.0130.1615No
83SLC38A3SLC38A3
Entrez,  Source
solute carrier family 38, member 37186-0.0130.1624No
84LAPTM5LAPTM5
Entrez,  Source
lysosomal associated multispanning membrane protein 57239-0.0140.1597No
85TTC1TTC1
Entrez,  Source
tetratricopeptide repeat domain 17298-0.0140.1565No
86GKN1GKN1
Entrez,  Source
gastrokine 17349-0.0150.1540No
87HCN3HCN3
Entrez,  Source
hyperpolarization activated cyclic nucleotide-gated potassium channel 37387-0.0150.1525No
88ADRA1AADRA1A
Entrez,  Source
adrenergic, alpha-1A-, receptor7837-0.0210.1204No
89MCART1MCART1
Entrez,  Source
mitochondrial carrier triple repeat 17845-0.0210.1217No
90PACSIN3PACSIN3
Entrez,  Source
protein kinase C and casein kinase substrate in neurons 37941-0.0230.1164No
91AP2M1AP2M1
Entrez,  Source
adaptor-related protein complex 2, mu 1 subunit8011-0.0240.1133No
92SNCBSNCB
Entrez,  Source
synuclein, beta8013-0.0240.1152No
93ABCF3ABCF3
Entrez,  Source
ATP-binding cassette, sub-family F (GCN20), member 38244-0.0270.1002No
94FOSL1FOSL1
Entrez,  Source
FOS-like antigen 18279-0.0280.1000No
95TOB1TOB1
Entrez,  Source
transducer of ERBB2, 18322-0.0280.0992No
96VDRVDR
Entrez,  Source
vitamin D (1,25- dihydroxyvitamin D3) receptor8460-0.0300.0915No
97LRRFIP2LRRFIP2
Entrez,  Source
leucine rich repeat (in FLII) interacting protein 28529-0.0310.0890No
98PKN3PKN3
Entrez,  Source
protein kinase N38543-0.0310.0907No
99SPRED1SPRED1
Entrez,  Source
sprouty-related, EVH1 domain containing 18719-0.0340.0804No
100CRYBA2CRYBA2
Entrez,  Source
crystallin, beta A28928-0.0370.0678No
101DTX2DTX2
Entrez,  Source
deltex homolog 2 (Drosophila)8976-0.0370.0675No
102MARK1MARK1
Entrez,  Source
MAP/microtubule affinity-regulating kinase 19011-0.0380.0682No
103POLD4POLD4
Entrez,  Source
polymerase (DNA-directed), delta 49014-0.0380.0713No
104HSPB8HSPB8
Entrez,  Source
heat shock 22kDa protein 89051-0.0380.0718No
105SYT2SYT2
Entrez,  Source
synaptotagmin II9396-0.0430.0496No
106CALB2CALB2
Entrez,  Source
calbindin 2, 29kDa (calretinin)9436-0.0440.0504No
107ANK3ANK3
Entrez,  Source
ankyrin 3, node of Ranvier (ankyrin G)9444-0.0440.0537No
108IL11IL11
Entrez,  Source
interleukin 1110189-0.0570.0022No
109GRIA1GRIA1
Entrez,  Source
glutamate receptor, ionotropic, AMPA 110271-0.0580.0011No
110EWSR1EWSR1
Entrez,  Source
Ewing sarcoma breakpoint region 110419-0.061-0.0048No
111SLC22A18SLC22A18
Entrez,  Source
solute carrier family 22 (organic cation transporter), member 1810589-0.064-0.0121No
112ATP6V1B2ATP6V1B2
Entrez,  Source
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B210631-0.065-0.0096No
113SYNGR1SYNGR1
Entrez,  Source
synaptogyrin 111243-0.080-0.0489No
114SLC26A1SLC26A1
Entrez,  Source
solute carrier family 26 (sulfate transporter), member 111762-0.094-0.0800No
115SMPXSMPX
Entrez,  Source
small muscle protein, X-linked11886-0.099-0.0808No
116EFNA1EFNA1
Entrez,  Source
ephrin-A111985-0.102-0.0794No
117PSME4PSME4
Entrez,  Source
proteasome (prosome, macropain) activator subunit 412096-0.107-0.0785No
118HEPHHEPH
Entrez,  Source
hephaestin12270-0.115-0.0817No
119PLEC1PLEC1
Entrez,  Source
plectin 1, intermediate filament binding protein 500kDa12297-0.116-0.0736No
120VAT1VAT1
Entrez,  Source
vesicle amine transport protein 1 homolog (T californica)12333-0.118-0.0661No
121METMET
Entrez,  Source
met proto-oncogene (hepatocyte growth factor receptor)12396-0.121-0.0604No
122CDH23CDH23
Entrez,  Source
cadherin-like 2312527-0.130-0.0590No
123CD68CD68
Entrez,  Source
CD68 molecule12573-0.133-0.0509No
124MMP9MMP9
Entrez,  Source
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)12642-0.137-0.0443No
125MAMDC2MAMDC2
Entrez,  Source
MAM domain containing 212670-0.139-0.0343No
126USP3USP3
Entrez,  Source
ubiquitin specific peptidase 312845-0.158-0.0338No
127DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A12862-0.160-0.0212No
128STAT5BSTAT5B
Entrez,  Source
signal transducer and activator of transcription 5B13204-0.257-0.0248No
129GADD45GGADD45G
Entrez,  Source
growth arrest and DNA-damage-inducible, gamma13302-0.4080.0030No
Table: GSEA details [plain text format]



Fig 2: V$AP1_C   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: V$AP1_C: Random ES distribution   
Gene set null distribution of ES for V$AP1_C