Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | V$AR_01 |
| Enrichment Score (ES) | -0.35393056 |
| Normalized Enrichment Score (NES) | -1.3026824 |
| Nominal p-value | 0.10462287 |
| FDR q-value | 0.55832094 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DCI | DCI Entrez, Source | dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase) | 164 | 0.350 | 0.0393 | No |
| 2 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 330 | 0.237 | 0.0618 | No |
| 3 | SDCBP2 | SDCBP2 Entrez, Source | syndecan binding protein (syntenin) 2 | 388 | 0.213 | 0.0890 | No |
| 4 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 389 | 0.213 | 0.1205 | No |
| 5 | PER2 | PER2 Entrez, Source | period homolog 2 (Drosophila) | 566 | 0.171 | 0.1324 | No |
| 6 | TGIF | TGIF Entrez, Source | TGFB-induced factor (TALE family homeobox) | 618 | 0.162 | 0.1525 | No |
| 7 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 694 | 0.151 | 0.1691 | No |
| 8 | NCDN | NCDN Entrez, Source | neurochondrin | 774 | 0.142 | 0.1842 | No |
| 9 | IHPK2 | IHPK2 Entrez, Source | inositol hexaphosphate kinase 2 | 835 | 0.136 | 0.1997 | No |
| 10 | CBLB | CBLB Entrez, Source | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 858 | 0.133 | 0.2177 | No |
| 11 | ADAM7 | ADAM7 Entrez, Source | ADAM metallopeptidase domain 7 | 1007 | 0.121 | 0.2245 | No |
| 12 | KLF15 | KLF15 Entrez, Source | Kruppel-like factor 15 | 1016 | 0.121 | 0.2416 | No |
| 13 | PER1 | PER1 Entrez, Source | period homolog 1 (Drosophila) | 1347 | 0.101 | 0.2317 | No |
| 14 | RTKN | RTKN Entrez, Source | rhotekin | 1476 | 0.095 | 0.2362 | No |
| 15 | KCNH2 | KCNH2 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 2139 | 0.069 | 0.1964 | No |
| 16 | C7ORF10 | C7ORF10 Entrez, Source | chromosome 7 open reading frame 10 | 2497 | 0.060 | 0.1784 | No |
| 17 | PSMA6 | PSMA6 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 6 | 2734 | 0.054 | 0.1686 | No |
| 18 | DTNB | DTNB Entrez, Source | dystrobrevin, beta | 2905 | 0.051 | 0.1632 | No |
| 19 | SNX1 | SNX1 Entrez, Source | sorting nexin 1 | 3339 | 0.042 | 0.1368 | No |
| 20 | SOX10 | SOX10 Entrez, Source | SRY (sex determining region Y)-box 10 | 3353 | 0.041 | 0.1419 | No |
| 21 | PMP22 | PMP22 Entrez, Source | peripheral myelin protein 22 | 3464 | 0.039 | 0.1394 | No |
| 22 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 3581 | 0.037 | 0.1362 | No |
| 23 | TXNIP | TXNIP Entrez, Source | thioredoxin interacting protein | 3975 | 0.031 | 0.1111 | No |
| 24 | SLC7A8 | SLC7A8 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 | 4160 | 0.028 | 0.1013 | No |
| 25 | FXYD1 | FXYD1 Entrez, Source | FXYD domain containing ion transport regulator 1 (phospholemman) | 4378 | 0.024 | 0.0885 | No |
| 26 | RAB10 | RAB10 Entrez, Source | RAB10, member RAS oncogene family | 4465 | 0.023 | 0.0854 | No |
| 27 | LUC7L | LUC7L Entrez, Source | LUC7-like (S. cerevisiae) | 4592 | 0.021 | 0.0790 | No |
| 28 | C11ORF11 | C11ORF11 Entrez, Source | chromosome 11 open reading frame 11 | 4744 | 0.019 | 0.0705 | No |
| 29 | SF3B1 | SF3B1 Entrez, Source | splicing factor 3b, subunit 1, 155kDa | 4753 | 0.019 | 0.0727 | No |
| 30 | OLFM1 | OLFM1 Entrez, Source | olfactomedin 1 | 4900 | 0.017 | 0.0641 | No |
| 31 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 5007 | 0.015 | 0.0584 | No |
| 32 | WNT7A | WNT7A Entrez, Source | wingless-type MMTV integration site family, member 7A | 5316 | 0.011 | 0.0368 | No |
| 33 | SCNN1A | SCNN1A Entrez, Source | sodium channel, nonvoltage-gated 1 alpha | 5333 | 0.011 | 0.0372 | No |
| 34 | PPP3CB | PPP3CB Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) | 5407 | 0.010 | 0.0331 | No |
| 35 | STX12 | STX12 Entrez, Source | syntaxin 12 | 5833 | 0.004 | 0.0017 | No |
| 36 | APPBP2 | APPBP2 Entrez, Source | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 5864 | 0.004 | -0.0000 | No |
| 37 | AMPH | AMPH Entrez, Source | amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen) | 5916 | 0.003 | -0.0034 | No |
| 38 | RBMS2 | RBMS2 Entrez, Source | RNA binding motif, single stranded interacting protein 2 | 6058 | 0.001 | -0.0138 | No |
| 39 | ELL2 | ELL2 Entrez, Source | elongation factor, RNA polymerase II, 2 | 6213 | -0.001 | -0.0253 | No |
| 40 | PITX3 | PITX3 Entrez, Source | paired-like homeodomain transcription factor 3 | 6413 | -0.003 | -0.0398 | No |
| 41 | NOTCH4 | NOTCH4 Entrez, Source | Notch homolog 4 (Drosophila) | 6512 | -0.005 | -0.0465 | No |
| 42 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 6937 | -0.010 | -0.0770 | No |
| 43 | SLC38A3 | SLC38A3 Entrez, Source | solute carrier family 38, member 3 | 7186 | -0.013 | -0.0938 | No |
| 44 | CALCRL | CALCRL Entrez, Source | calcitonin receptor-like | 7260 | -0.014 | -0.0973 | No |
| 45 | SYMPK | SYMPK Entrez, Source | symplekin | 7266 | -0.014 | -0.0956 | No |
| 46 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 7976 | -0.023 | -0.1456 | No |
| 47 | ITPKB | ITPKB Entrez, Source | inositol 1,4,5-trisphosphate 3-kinase B | 8579 | -0.032 | -0.1863 | No |
| 48 | DBC1 | DBC1 Entrez, Source | deleted in bladder cancer 1 | 8614 | -0.032 | -0.1841 | No |
| 49 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 8712 | -0.034 | -0.1864 | No |
| 50 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 8997 | -0.038 | -0.2022 | No |
| 51 | SNAP25 | SNAP25 Entrez, Source | synaptosomal-associated protein, 25kDa | 9178 | -0.040 | -0.2099 | No |
| 52 | ITGA7 | ITGA7 Entrez, Source | integrin, alpha 7 | 9373 | -0.043 | -0.2182 | No |
| 53 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 9509 | -0.045 | -0.2217 | No |
| 54 | DAB2IP | DAB2IP Entrez, Source | DAB2 interacting protein | 9534 | -0.046 | -0.2167 | No |
| 55 | ANGPTL2 | ANGPTL2 Entrez, Source | angiopoietin-like 2 | 9536 | -0.046 | -0.2100 | No |
| 56 | KCNA5 | KCNA5 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 5 | 9542 | -0.046 | -0.2036 | No |
| 57 | FILIP1 | FILIP1 Entrez, Source | filamin A interacting protein 1 | 9962 | -0.053 | -0.2274 | No |
| 58 | STOML2 | STOML2 Entrez, Source | stomatin (EPB72)-like 2 | 10942 | -0.072 | -0.2905 | No |
| 59 | SIX1 | SIX1 Entrez, Source | sine oculis homeobox homolog 1 (Drosophila) | 11186 | -0.078 | -0.2973 | No |
| 60 | ADNP | ADNP Entrez, Source | activity-dependent neuroprotector | 11378 | -0.083 | -0.2994 | No |
| 61 | SLC29A2 | SLC29A2 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 2 | 12103 | -0.107 | -0.3381 | Yes |
| 62 | PSME2 | PSME2 Entrez, Source | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 12234 | -0.113 | -0.3312 | Yes |
| 63 | SIPA1 | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 12263 | -0.115 | -0.3164 | Yes |
| 64 | PRKCBP1 | PRKCBP1 Entrez, Source | protein kinase C binding protein 1 | 12402 | -0.121 | -0.3089 | Yes |
| 65 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 12425 | -0.123 | -0.2924 | Yes |
| 66 | ABTB2 | ABTB2 Entrez, Source | ankyrin repeat and BTB (POZ) domain containing 2 | 12516 | -0.129 | -0.2801 | Yes |
| 67 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 13029 | -0.193 | -0.2902 | Yes |
| 68 | FOXA3 | FOXA3 Entrez, Source | forkhead box A3 | 13076 | -0.203 | -0.2637 | Yes |
| 69 | LIFR | LIFR Entrez, Source | leukemia inhibitory factor receptor alpha | 13146 | -0.224 | -0.2358 | Yes |
| 70 | JAK2 | JAK2 Entrez, Source | Janus kinase 2 (a protein tyrosine kinase) | 13193 | -0.251 | -0.2022 | Yes |
| 71 | CSAD | CSAD Entrez, Source | cysteine sulfinic acid decarboxylase | 13323 | -0.529 | -0.1338 | Yes |
| 72 | EDG1 | EDG1 Entrez, Source | endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 | 13341 | -0.915 | 0.0001 | Yes |
