Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | V$COUP_01 |
| Enrichment Score (ES) | -0.3147689 |
| Normalized Enrichment Score (NES) | -1.2560391 |
| Nominal p-value | 0.089238845 |
| FDR q-value | 0.61104614 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 60 | 0.555 | 0.0441 | No |
| 2 | MYBPH | MYBPH Entrez, Source | myosin binding protein H | 124 | 0.396 | 0.0741 | No |
| 3 | CREB3L3 | CREB3L3 Entrez, Source | cAMP responsive element binding protein 3-like 3 | 154 | 0.359 | 0.1034 | No |
| 4 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 162 | 0.351 | 0.1336 | No |
| 5 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 222 | 0.305 | 0.1558 | No |
| 6 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 335 | 0.235 | 0.1679 | No |
| 7 | GYS2 | GYS2 Entrez, Source | glycogen synthase 2 (liver) | 371 | 0.219 | 0.1845 | No |
| 8 | TNFRSF12A | TNFRSF12A Entrez, Source | tumor necrosis factor receptor superfamily, member 12A | 415 | 0.205 | 0.1992 | No |
| 9 | LMO3 | LMO3 Entrez, Source | LIM domain only 3 (rhombotin-like 2) | 573 | 0.169 | 0.2021 | No |
| 10 | NCDN | NCDN Entrez, Source | neurochondrin | 774 | 0.142 | 0.1994 | No |
| 11 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 806 | 0.139 | 0.2093 | No |
| 12 | PITX2 | PITX2 Entrez, Source | paired-like homeodomain transcription factor 2 | 850 | 0.134 | 0.2178 | No |
| 13 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1068 | 0.116 | 0.2116 | No |
| 14 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 1234 | 0.108 | 0.2086 | No |
| 15 | DCTN1 | DCTN1 Entrez, Source | dynactin 1 (p150, glued homolog, Drosophila) | 1493 | 0.094 | 0.1973 | No |
| 16 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 1934 | 0.075 | 0.1706 | No |
| 17 | FGF12 | FGF12 Entrez, Source | fibroblast growth factor 12 | 1947 | 0.075 | 0.1763 | No |
| 18 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 2140 | 0.069 | 0.1678 | No |
| 19 | CRABP2 | CRABP2 Entrez, Source | cellular retinoic acid binding protein 2 | 2566 | 0.058 | 0.1407 | No |
| 20 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 2881 | 0.051 | 0.1215 | No |
| 21 | RNF103 | RNF103 Entrez, Source | ring finger protein 103 | 2952 | 0.050 | 0.1206 | No |
| 22 | NR4A3 | NR4A3 Entrez, Source | nuclear receptor subfamily 4, group A, member 3 | 2974 | 0.049 | 0.1233 | No |
| 23 | MARK2 | MARK2 Entrez, Source | MAP/microtubule affinity-regulating kinase 2 | 3099 | 0.047 | 0.1180 | No |
| 24 | HSD17B8 | HSD17B8 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 8 | 3145 | 0.045 | 0.1186 | No |
| 25 | SMOC1 | SMOC1 Entrez, Source | SPARC related modular calcium binding 1 | 3292 | 0.043 | 0.1113 | No |
| 26 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 3304 | 0.042 | 0.1142 | No |
| 27 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 3396 | 0.041 | 0.1108 | No |
| 28 | PTHR1 | PTHR1 Entrez, Source | parathyroid hormone receptor 1 | 3437 | 0.040 | 0.1113 | No |
| 29 | EFNB1 | EFNB1 Entrez, Source | ephrin-B1 | 3795 | 0.034 | 0.0872 | No |
| 30 | PRKRA | PRKRA Entrez, Source | protein kinase, interferon-inducible double stranded RNA dependent activator | 4030 | 0.030 | 0.0722 | No |
| 31 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 4355 | 0.025 | 0.0498 | No |
| 32 | ZDHHC3 | ZDHHC3 Entrez, Source | zinc finger, DHHC-type containing 3 | 4396 | 0.024 | 0.0489 | No |
| 33 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 4662 | 0.020 | 0.0306 | No |
| 34 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 4727 | 0.019 | 0.0275 | No |
| 35 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 5296 | 0.011 | -0.0145 | No |
| 36 | ESRRG | ESRRG Entrez, Source | estrogen-related receptor gamma | 5378 | 0.010 | -0.0197 | No |
| 37 | LMNA | LMNA Entrez, Source | lamin A/C | 5805 | 0.004 | -0.0516 | No |
| 38 | AP1B1 | AP1B1 Entrez, Source | adaptor-related protein complex 1, beta 1 subunit | 5923 | 0.003 | -0.0601 | No |
| 39 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 6392 | -0.003 | -0.0952 | No |
| 40 | DNAJA2 | DNAJA2 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 2 | 6450 | -0.004 | -0.0992 | No |
| 41 | SLC7A9 | SLC7A9 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 | 7007 | -0.011 | -0.1403 | No |
| 42 | GBL | GBL Entrez, Source | - | 7083 | -0.012 | -0.1450 | No |
| 43 | DLX5 | DLX5 Entrez, Source | distal-less homeobox 5 | 7118 | -0.012 | -0.1465 | No |
| 44 | CRYGC | CRYGC Entrez, Source | crystallin, gamma C | 7178 | -0.013 | -0.1498 | No |
| 45 | SYMPK | SYMPK Entrez, Source | symplekin | 7266 | -0.014 | -0.1552 | No |
| 46 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 7269 | -0.014 | -0.1541 | No |
| 47 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 7289 | -0.014 | -0.1543 | No |
| 48 | PTMS | PTMS Entrez, Source | parathymosin | 7316 | -0.014 | -0.1550 | No |
| 49 | WBP4 | WBP4 Entrez, Source | WW domain binding protein 4 (formin binding protein 21) | 7400 | -0.015 | -0.1600 | No |
| 50 | CREB3L2 | CREB3L2 Entrez, Source | cAMP responsive element binding protein 3-like 2 | 7447 | -0.016 | -0.1620 | No |
| 51 | MLLT10 | MLLT10 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 7737 | -0.020 | -0.1821 | No |
| 52 | TBX5 | TBX5 Entrez, Source | T-box 5 | 7774 | -0.020 | -0.1831 | No |
| 53 | ADRA1A | ADRA1A Entrez, Source | adrenergic, alpha-1A-, receptor | 7837 | -0.021 | -0.1859 | No |
| 54 | LZIC | LZIC Entrez, Source | leucine zipper and CTNNBIP1 domain containing | 7908 | -0.022 | -0.1893 | No |
| 55 | DOCK11 | DOCK11 Entrez, Source | dedicator of cytokinesis 11 | 7970 | -0.023 | -0.1918 | No |
| 56 | ARHGEF7 | ARHGEF7 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 7 | 7999 | -0.023 | -0.1919 | No |
| 57 | TCF1 | TCF1 Entrez, Source | transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor | 8123 | -0.025 | -0.1990 | No |
| 58 | FOXA1 | FOXA1 Entrez, Source | forkhead box A1 | 8131 | -0.026 | -0.1973 | No |
| 59 | NEK6 | NEK6 Entrez, Source | NIMA (never in mitosis gene a)-related kinase 6 | 8247 | -0.027 | -0.2036 | No |
| 60 | LGI4 | LGI4 Entrez, Source | leucine-rich repeat LGI family, member 4 | 8400 | -0.029 | -0.2125 | No |
| 61 | TCF2 | TCF2 Entrez, Source | transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor | 8766 | -0.034 | -0.2371 | No |
| 62 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 8836 | -0.035 | -0.2392 | No |
| 63 | RBBP6 | RBBP6 Entrez, Source | retinoblastoma binding protein 6 | 8839 | -0.035 | -0.2363 | No |
| 64 | HPN | HPN Entrez, Source | hepsin (transmembrane protease, serine 1) | 8962 | -0.037 | -0.2423 | No |
| 65 | OTP | OTP Entrez, Source | orthopedia homolog (Drosophila) | 9009 | -0.038 | -0.2424 | No |
| 66 | PABPN1 | PABPN1 Entrez, Source | poly(A) binding protein, nuclear 1 | 9064 | -0.038 | -0.2431 | No |
| 67 | ANGPT1 | ANGPT1 Entrez, Source | angiopoietin 1 | 9136 | -0.039 | -0.2451 | No |
| 68 | TNNI1 | TNNI1 Entrez, Source | troponin I type 1 (skeletal, slow) | 9147 | -0.039 | -0.2424 | No |
| 69 | RTN2 | RTN2 Entrez, Source | reticulon 2 | 9234 | -0.041 | -0.2453 | No |
| 70 | JMJD1C | JMJD1C Entrez, Source | jumonji domain containing 1C | 9316 | -0.042 | -0.2478 | No |
| 71 | PGF | PGF Entrez, Source | placental growth factor, vascular endothelial growth factor-related protein | 9350 | -0.043 | -0.2465 | No |
| 72 | DNMT3A | DNMT3A Entrez, Source | DNA (cytosine-5-)-methyltransferase 3 alpha | 9385 | -0.043 | -0.2453 | No |
| 73 | DDB1 | DDB1 Entrez, Source | damage-specific DNA binding protein 1, 127kDa | 9492 | -0.045 | -0.2494 | No |
| 74 | LGALS4 | LGALS4 Entrez, Source | lectin, galactoside-binding, soluble, 4 (galectin 4) | 9494 | -0.045 | -0.2455 | No |
| 75 | DAB2IP | DAB2IP Entrez, Source | DAB2 interacting protein | 9534 | -0.046 | -0.2445 | No |
| 76 | PCTK1 | PCTK1 Entrez, Source | PCTAIRE protein kinase 1 | 9584 | -0.047 | -0.2441 | No |
| 77 | SLC11A2 | SLC11A2 Entrez, Source | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 9701 | -0.049 | -0.2486 | No |
| 78 | APOM | APOM Entrez, Source | apolipoprotein M | 9750 | -0.049 | -0.2479 | No |
| 79 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 9821 | -0.051 | -0.2488 | No |
| 80 | SLC9A3 | SLC9A3 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 3 | 10239 | -0.057 | -0.2753 | No |
| 81 | TPCN1 | TPCN1 Entrez, Source | two pore segment channel 1 | 10284 | -0.058 | -0.2735 | No |
| 82 | RBP2 | RBP2 Entrez, Source | retinol binding protein 2, cellular | 10395 | -0.060 | -0.2765 | No |
| 83 | NET1 | NET1 Entrez, Source | neuroepithelial cell transforming gene 1 | 10614 | -0.065 | -0.2874 | No |
| 84 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 10672 | -0.066 | -0.2859 | No |
| 85 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 10686 | -0.066 | -0.2811 | No |
| 86 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 10861 | -0.070 | -0.2881 | No |
| 87 | MRPL2 | MRPL2 Entrez, Source | mitochondrial ribosomal protein L2 | 10912 | -0.071 | -0.2857 | No |
| 88 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10927 | -0.072 | -0.2805 | No |
| 89 | STOML2 | STOML2 Entrez, Source | stomatin (EPB72)-like 2 | 10942 | -0.072 | -0.2752 | No |
| 90 | TOMM70A | TOMM70A Entrez, Source | translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) | 11072 | -0.075 | -0.2784 | No |
| 91 | PPP2R5D | PPP2R5D Entrez, Source | protein phosphatase 2, regulatory subunit B (B56), delta isoform | 11192 | -0.078 | -0.2806 | No |
| 92 | GATA4 | GATA4 Entrez, Source | GATA binding protein 4 | 11355 | -0.083 | -0.2856 | No |
| 93 | PDE3B | PDE3B Entrez, Source | phosphodiesterase 3B, cGMP-inhibited | 11375 | -0.083 | -0.2797 | No |
| 94 | ZPBP2 | ZPBP2 Entrez, Source | zona pellucida binding protein 2 | 11453 | -0.085 | -0.2781 | No |
| 95 | AGPS | AGPS Entrez, Source | alkylglycerone phosphate synthase | 11901 | -0.099 | -0.3032 | No |
| 96 | TIMELESS | TIMELESS Entrez, Source | timeless homolog (Drosophila) | 11937 | -0.100 | -0.2970 | No |
| 97 | SLC26A3 | SLC26A3 Entrez, Source | solute carrier family 26, member 3 | 12081 | -0.106 | -0.2985 | No |
| 98 | PLEC1 | PLEC1 Entrez, Source | plectin 1, intermediate filament binding protein 500kDa | 12297 | -0.116 | -0.3046 | Yes |
| 99 | GJB2 | GJB2 Entrez, Source | gap junction protein, beta 2, 26kDa (connexin 26) | 12323 | -0.117 | -0.2962 | Yes |
| 100 | SERPINC1 | SERPINC1 Entrez, Source | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 12565 | -0.133 | -0.3028 | Yes |
| 101 | BMF | BMF Entrez, Source | Bcl2 modifying factor | 12660 | -0.138 | -0.2978 | Yes |
| 102 | ADRB2 | ADRB2 Entrez, Source | adrenergic, beta-2-, receptor, surface | 12708 | -0.142 | -0.2889 | Yes |
| 103 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 12718 | -0.143 | -0.2771 | Yes |
| 104 | SERPIND1 | SERPIND1 Entrez, Source | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 12846 | -0.158 | -0.2728 | Yes |
| 105 | FGFR3 | FGFR3 Entrez, Source | fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) | 12848 | -0.158 | -0.2590 | Yes |
| 106 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 12922 | -0.168 | -0.2498 | Yes |
| 107 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 12962 | -0.175 | -0.2375 | Yes |
| 108 | FOXA3 | FOXA3 Entrez, Source | forkhead box A3 | 13076 | -0.203 | -0.2282 | Yes |
| 109 | ASGR2 | ASGR2 Entrez, Source | asialoglycoprotein receptor 2 | 13216 | -0.269 | -0.2152 | Yes |
| 110 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 13227 | -0.274 | -0.1919 | Yes |
| 111 | ARFGEF2 | ARFGEF2 Entrez, Source | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 13245 | -0.293 | -0.1675 | Yes |
| 112 | PON1 | PON1 Entrez, Source | paraoxonase 1 | 13297 | -0.394 | -0.1368 | Yes |
| 113 | PKLR | PKLR Entrez, Source | pyruvate kinase, liver and RBC | 13313 | -0.446 | -0.0989 | Yes |
| 114 | LTB | LTB Entrez, Source | lymphotoxin beta (TNF superfamily, member 3) | 13327 | -0.568 | -0.0501 | Yes |
| 115 | SLC7A7 | SLC7A7 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 | 13328 | -0.584 | 0.0011 | Yes |
