Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | V$E2F1_Q3 |
| Enrichment Score (ES) | -0.3613776 |
| Normalized Enrichment Score (NES) | -1.3655971 |
| Nominal p-value | 0.05109489 |
| FDR q-value | 0.48613074 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 57 | 0.561 | 0.0689 | No |
| 2 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 389 | 0.213 | 0.0717 | No |
| 3 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 473 | 0.188 | 0.0900 | No |
| 4 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 744 | 0.145 | 0.0885 | No |
| 5 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 780 | 0.141 | 0.1043 | No |
| 6 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 849 | 0.134 | 0.1167 | No |
| 7 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 1250 | 0.107 | 0.1005 | No |
| 8 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 1398 | 0.099 | 0.1023 | No |
| 9 | ATP1B4 | ATP1B4 Entrez, Source | ATPase, (Na+)/K+ transporting, beta 4 polypeptide | 1447 | 0.096 | 0.1112 | No |
| 10 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 1551 | 0.091 | 0.1154 | No |
| 11 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 1884 | 0.077 | 0.1004 | No |
| 12 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 2181 | 0.068 | 0.0869 | No |
| 13 | SYT6 | SYT6 Entrez, Source | synaptotagmin VI | 2331 | 0.064 | 0.0840 | No |
| 14 | CORT | CORT Entrez, Source | cortistatin | 2383 | 0.062 | 0.0883 | No |
| 15 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 2512 | 0.059 | 0.0864 | No |
| 16 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 2830 | 0.052 | 0.0692 | No |
| 17 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 2842 | 0.052 | 0.0752 | No |
| 18 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 3347 | 0.042 | 0.0426 | No |
| 19 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 3405 | 0.040 | 0.0435 | No |
| 20 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 3441 | 0.040 | 0.0461 | No |
| 21 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 3568 | 0.037 | 0.0414 | No |
| 22 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 3581 | 0.037 | 0.0454 | No |
| 23 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 3593 | 0.037 | 0.0494 | No |
| 24 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 3681 | 0.036 | 0.0474 | No |
| 25 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 3699 | 0.035 | 0.0507 | No |
| 26 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 3799 | 0.033 | 0.0476 | No |
| 27 | SYT11 | SYT11 Entrez, Source | synaptotagmin XI | 3867 | 0.032 | 0.0468 | No |
| 28 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 3943 | 0.031 | 0.0452 | No |
| 29 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 3994 | 0.030 | 0.0454 | No |
| 30 | BARHL1 | BARHL1 Entrez, Source | BarH-like 1 (Drosophila) | 4137 | 0.028 | 0.0383 | No |
| 31 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 4293 | 0.026 | 0.0300 | No |
| 32 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 4355 | 0.025 | 0.0286 | No |
| 33 | PELP1 | PELP1 Entrez, Source | proline, glutamic acid and leucine rich protein 1 | 5522 | 0.008 | -0.0584 | No |
| 34 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 5851 | 0.004 | -0.0826 | No |
| 35 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5938 | 0.003 | -0.0887 | No |
| 36 | TMPO | TMPO Entrez, Source | thymopoietin | 6281 | -0.002 | -0.1143 | No |
| 37 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 6398 | -0.003 | -0.1227 | No |
| 38 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 6442 | -0.004 | -0.1254 | No |
| 39 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 6500 | -0.004 | -0.1291 | No |
| 40 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 6695 | -0.007 | -0.1429 | No |
| 41 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 6700 | -0.007 | -0.1422 | No |
| 42 | BAT3 | BAT3 Entrez, Source | HLA-B associated transcript 3 | 6821 | -0.008 | -0.1502 | No |
| 43 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 7191 | -0.013 | -0.1764 | No |
| 44 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 7279 | -0.014 | -0.1811 | No |
| 45 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 7385 | -0.015 | -0.1870 | No |
| 46 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 7387 | -0.015 | -0.1851 | No |
| 47 | SLC25A3 | SLC25A3 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 7848 | -0.021 | -0.2171 | No |
| 48 | ADCY8 | ADCY8 Entrez, Source | adenylate cyclase 8 (brain) | 8194 | -0.026 | -0.2396 | No |
| 49 | GRIK2 | GRIK2 Entrez, Source | glutamate receptor, ionotropic, kainate 2 | 8215 | -0.027 | -0.2377 | No |
| 50 | TCP1 | TCP1 Entrez, Source | t-complex 1 | 8504 | -0.031 | -0.2554 | No |
| 51 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 8594 | -0.032 | -0.2579 | No |
| 52 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 8663 | -0.033 | -0.2587 | No |
| 53 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 8836 | -0.035 | -0.2671 | No |
| 54 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 8969 | -0.037 | -0.2722 | No |
| 55 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 9219 | -0.040 | -0.2857 | No |
| 56 | NCL | NCL Entrez, Source | nucleolin | 9448 | -0.044 | -0.2971 | No |
| 57 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 9637 | -0.048 | -0.3051 | No |
| 58 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 9770 | -0.050 | -0.3086 | No |
| 59 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 9789 | -0.050 | -0.3034 | No |
| 60 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 9821 | -0.051 | -0.2992 | No |
| 61 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9987 | -0.053 | -0.3047 | No |
| 62 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 10524 | -0.063 | -0.3369 | No |
| 63 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 10849 | -0.070 | -0.3523 | Yes |
| 64 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10927 | -0.072 | -0.3488 | Yes |
| 65 | TRIM39 | TRIM39 Entrez, Source | tripartite motif-containing 39 | 10945 | -0.072 | -0.3407 | Yes |
| 66 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 11103 | -0.076 | -0.3426 | Yes |
| 67 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11343 | -0.083 | -0.3499 | Yes |
| 68 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 11457 | -0.085 | -0.3473 | Yes |
| 69 | ABCE1 | ABCE1 Entrez, Source | ATP-binding cassette, sub-family E (OABP), member 1 | 11622 | -0.090 | -0.3480 | Yes |
| 70 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 11624 | -0.090 | -0.3364 | Yes |
| 71 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 11671 | -0.091 | -0.3280 | Yes |
| 72 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11823 | -0.096 | -0.3268 | Yes |
| 73 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12174 | -0.110 | -0.3388 | Yes |
| 74 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 12208 | -0.112 | -0.3268 | Yes |
| 75 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 12214 | -0.112 | -0.3125 | Yes |
| 76 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 12279 | -0.115 | -0.3024 | Yes |
| 77 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 12427 | -0.123 | -0.2975 | Yes |
| 78 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 12440 | -0.123 | -0.2823 | Yes |
| 79 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12447 | -0.123 | -0.2666 | Yes |
| 80 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 12463 | -0.125 | -0.2515 | Yes |
| 81 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12532 | -0.130 | -0.2397 | Yes |
| 82 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 12570 | -0.133 | -0.2251 | Yes |
| 83 | SHMT1 | SHMT1 Entrez, Source | serine hydroxymethyltransferase 1 (soluble) | 12628 | -0.136 | -0.2117 | Yes |
| 84 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12652 | -0.138 | -0.1954 | Yes |
| 85 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12677 | -0.140 | -0.1790 | Yes |
| 86 | SSBP3 | SSBP3 Entrez, Source | single stranded DNA binding protein 3 | 12700 | -0.142 | -0.1622 | Yes |
| 87 | DCK | DCK Entrez, Source | deoxycytidine kinase | 12784 | -0.151 | -0.1489 | Yes |
| 88 | XTP3TPA | XTP3TPA Entrez, Source | - | 12898 | -0.165 | -0.1359 | Yes |
| 89 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 12922 | -0.168 | -0.1158 | Yes |
| 90 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13114 | -0.214 | -0.1023 | Yes |
| 91 | ASCL1 | ASCL1 Entrez, Source | achaete-scute complex-like 1 (Drosophila) | 13340 | -0.915 | 0.0002 | Yes |
