Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | V$E2F1_Q4_01 |
| Enrichment Score (ES) | -0.32903442 |
| Normalized Enrichment Score (NES) | -1.2592236 |
| Nominal p-value | 0.09470752 |
| FDR q-value | 0.6204501 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 366 | 0.223 | 0.0054 | No |
| 2 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 389 | 0.213 | 0.0354 | No |
| 3 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 473 | 0.188 | 0.0570 | No |
| 4 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 694 | 0.151 | 0.0627 | No |
| 5 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 780 | 0.141 | 0.0773 | No |
| 6 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 936 | 0.126 | 0.0843 | No |
| 7 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 1001 | 0.121 | 0.0975 | No |
| 8 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 1021 | 0.119 | 0.1137 | No |
| 9 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 1140 | 0.113 | 0.1215 | No |
| 10 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 1338 | 0.102 | 0.1218 | No |
| 11 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 1398 | 0.099 | 0.1320 | No |
| 12 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 1606 | 0.089 | 0.1295 | No |
| 13 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 1672 | 0.086 | 0.1374 | No |
| 14 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 1690 | 0.085 | 0.1487 | No |
| 15 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 2181 | 0.068 | 0.1218 | No |
| 16 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 2842 | 0.052 | 0.0797 | No |
| 17 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 3272 | 0.043 | 0.0537 | No |
| 18 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 3452 | 0.040 | 0.0460 | No |
| 19 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 3568 | 0.037 | 0.0429 | No |
| 20 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 3593 | 0.037 | 0.0466 | No |
| 21 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 3653 | 0.036 | 0.0475 | No |
| 22 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 3726 | 0.035 | 0.0472 | No |
| 23 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 3800 | 0.033 | 0.0466 | No |
| 24 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 3967 | 0.031 | 0.0387 | No |
| 25 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 3994 | 0.030 | 0.0412 | No |
| 26 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 4101 | 0.029 | 0.0375 | No |
| 27 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 4251 | 0.026 | 0.0301 | No |
| 28 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 4293 | 0.026 | 0.0308 | No |
| 29 | CHGB | CHGB Entrez, Source | chromogranin B (secretogranin 1) | 4848 | 0.017 | -0.0084 | No |
| 30 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 4880 | 0.017 | -0.0083 | No |
| 31 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 5196 | 0.013 | -0.0301 | No |
| 32 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 5390 | 0.010 | -0.0432 | No |
| 33 | FBXO9 | FBXO9 Entrez, Source | F-box protein 9 | 5615 | 0.007 | -0.0591 | No |
| 34 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 5787 | 0.005 | -0.0713 | No |
| 35 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 5851 | 0.004 | -0.0755 | No |
| 36 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5938 | 0.003 | -0.0816 | No |
| 37 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 5939 | 0.003 | -0.0812 | No |
| 38 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 6070 | 0.001 | -0.0908 | No |
| 39 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 6189 | -0.000 | -0.0996 | No |
| 40 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 6398 | -0.003 | -0.1149 | No |
| 41 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 6574 | -0.005 | -0.1273 | No |
| 42 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 6695 | -0.007 | -0.1353 | No |
| 43 | DHX40 | DHX40 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 6817 | -0.008 | -0.1432 | No |
| 44 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 7191 | -0.013 | -0.1694 | No |
| 45 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 7262 | -0.014 | -0.1726 | No |
| 46 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 7279 | -0.014 | -0.1718 | No |
| 47 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 7633 | -0.019 | -0.1957 | No |
| 48 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 7715 | -0.020 | -0.1989 | No |
| 49 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7792 | -0.021 | -0.2016 | No |
| 50 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 7809 | -0.021 | -0.1997 | No |
| 51 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 7992 | -0.023 | -0.2099 | No |
| 52 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8111 | -0.025 | -0.2151 | No |
| 53 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 8535 | -0.031 | -0.2424 | No |
| 54 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 8663 | -0.033 | -0.2471 | No |
| 55 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 8808 | -0.035 | -0.2528 | No |
| 56 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 8997 | -0.038 | -0.2614 | No |
| 57 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 9053 | -0.038 | -0.2599 | No |
| 58 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 9294 | -0.042 | -0.2718 | No |
| 59 | NCL | NCL Entrez, Source | nucleolin | 9448 | -0.044 | -0.2768 | No |
| 60 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 9466 | -0.044 | -0.2715 | No |
| 61 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 9637 | -0.048 | -0.2773 | No |
| 62 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 9789 | -0.050 | -0.2812 | No |
| 63 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9987 | -0.053 | -0.2882 | No |
| 64 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 10524 | -0.063 | -0.3193 | Yes |
| 65 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 10568 | -0.064 | -0.3132 | Yes |
| 66 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10688 | -0.066 | -0.3124 | Yes |
| 67 | PELO | PELO Entrez, Source | pelota homolog (Drosophila) | 10844 | -0.069 | -0.3138 | Yes |
| 68 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 10981 | -0.073 | -0.3132 | Yes |
| 69 | RHD | RHD Entrez, Source | Rh blood group, D antigen | 11014 | -0.074 | -0.3047 | Yes |
| 70 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 11337 | -0.082 | -0.3168 | Yes |
| 71 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 11457 | -0.085 | -0.3131 | Yes |
| 72 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 11624 | -0.090 | -0.3124 | Yes |
| 73 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 11671 | -0.091 | -0.3024 | Yes |
| 74 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11823 | -0.096 | -0.2995 | Yes |
| 75 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 11934 | -0.100 | -0.2930 | Yes |
| 76 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 11995 | -0.103 | -0.2822 | Yes |
| 77 | HTF9C | HTF9C Entrez, Source | - | 12171 | -0.110 | -0.2791 | Yes |
| 78 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12174 | -0.110 | -0.2629 | Yes |
| 79 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12210 | -0.112 | -0.2489 | Yes |
| 80 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 12279 | -0.115 | -0.2370 | Yes |
| 81 | NUP155 | NUP155 Entrez, Source | nucleoporin 155kDa | 12330 | -0.118 | -0.2234 | Yes |
| 82 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 12427 | -0.123 | -0.2124 | Yes |
| 83 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 12451 | -0.124 | -0.1958 | Yes |
| 84 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 12463 | -0.125 | -0.1781 | Yes |
| 85 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 12470 | -0.125 | -0.1600 | Yes |
| 86 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12677 | -0.140 | -0.1549 | Yes |
| 87 | DCK | DCK Entrez, Source | deoxycytidine kinase | 12784 | -0.151 | -0.1405 | Yes |
| 88 | XTP3TPA | XTP3TPA Entrez, Source | - | 12898 | -0.165 | -0.1247 | Yes |
| 89 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 12922 | -0.168 | -0.1016 | Yes |
| 90 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13096 | -0.208 | -0.0838 | Yes |
| 91 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13114 | -0.214 | -0.0533 | Yes |
| 92 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13317 | -0.475 | 0.0019 | Yes |
