Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | V$E2F_Q4_01 |
| Enrichment Score (ES) | -0.33724108 |
| Normalized Enrichment Score (NES) | -1.2885875 |
| Nominal p-value | 0.083333336 |
| FDR q-value | 0.56961536 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 145 | 0.367 | 0.0438 | No |
| 2 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 366 | 0.223 | 0.0605 | No |
| 3 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 389 | 0.213 | 0.0907 | No |
| 4 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 473 | 0.188 | 0.1125 | No |
| 5 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 694 | 0.151 | 0.1184 | No |
| 6 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 780 | 0.141 | 0.1331 | No |
| 7 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 1001 | 0.121 | 0.1347 | No |
| 8 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 1021 | 0.119 | 0.1511 | No |
| 9 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 1140 | 0.113 | 0.1590 | No |
| 10 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 1338 | 0.102 | 0.1594 | No |
| 11 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 1690 | 0.085 | 0.1456 | No |
| 12 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 1884 | 0.077 | 0.1426 | No |
| 13 | DIO3 | DIO3 Entrez, Source | deiodinase, iodothyronine, type III | 1924 | 0.075 | 0.1509 | No |
| 14 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 2181 | 0.068 | 0.1417 | No |
| 15 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 3272 | 0.043 | 0.0659 | No |
| 16 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 3452 | 0.040 | 0.0583 | No |
| 17 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 3568 | 0.037 | 0.0552 | No |
| 18 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 3593 | 0.037 | 0.0590 | No |
| 19 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 3653 | 0.036 | 0.0599 | No |
| 20 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 3726 | 0.035 | 0.0596 | No |
| 21 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 3800 | 0.033 | 0.0591 | No |
| 22 | SYT11 | SYT11 Entrez, Source | synaptotagmin XI | 3867 | 0.032 | 0.0590 | No |
| 23 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 3943 | 0.031 | 0.0580 | No |
| 24 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 3967 | 0.031 | 0.0608 | No |
| 25 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 3994 | 0.030 | 0.0634 | No |
| 26 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 4251 | 0.026 | 0.0480 | No |
| 27 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 4293 | 0.026 | 0.0487 | No |
| 28 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 4880 | 0.017 | 0.0070 | No |
| 29 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 5196 | 0.013 | -0.0148 | No |
| 30 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 5390 | 0.010 | -0.0279 | No |
| 31 | FBXO9 | FBXO9 Entrez, Source | F-box protein 9 | 5615 | 0.007 | -0.0438 | No |
| 32 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 5851 | 0.004 | -0.0609 | No |
| 33 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5938 | 0.003 | -0.0670 | No |
| 34 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 5939 | 0.003 | -0.0665 | No |
| 35 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 6070 | 0.001 | -0.0762 | No |
| 36 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 6189 | -0.000 | -0.0850 | No |
| 37 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 6398 | -0.003 | -0.1002 | No |
| 38 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 6442 | -0.004 | -0.1029 | No |
| 39 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 6574 | -0.005 | -0.1120 | No |
| 40 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 6695 | -0.007 | -0.1200 | No |
| 41 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 6929 | -0.010 | -0.1361 | No |
| 42 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 7262 | -0.014 | -0.1591 | No |
| 43 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 7279 | -0.014 | -0.1582 | No |
| 44 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 7651 | -0.019 | -0.1834 | No |
| 45 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 7715 | -0.020 | -0.1852 | No |
| 46 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7792 | -0.021 | -0.1879 | No |
| 47 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 7809 | -0.021 | -0.1860 | No |
| 48 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8111 | -0.025 | -0.2049 | No |
| 49 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 8535 | -0.031 | -0.2322 | No |
| 50 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 8594 | -0.032 | -0.2318 | No |
| 51 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 8808 | -0.035 | -0.2426 | No |
| 52 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 8947 | -0.037 | -0.2475 | No |
| 53 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 8997 | -0.038 | -0.2456 | No |
| 54 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 9053 | -0.038 | -0.2440 | No |
| 55 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 9219 | -0.040 | -0.2504 | No |
| 56 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 9294 | -0.042 | -0.2498 | No |
| 57 | NCL | NCL Entrez, Source | nucleolin | 9448 | -0.044 | -0.2547 | No |
| 58 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 9466 | -0.044 | -0.2494 | No |
| 59 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 9637 | -0.048 | -0.2551 | No |
| 60 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 9789 | -0.050 | -0.2590 | No |
| 61 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9987 | -0.053 | -0.2659 | No |
| 62 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 10568 | -0.064 | -0.3002 | No |
| 63 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10688 | -0.066 | -0.2993 | No |
| 64 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 10981 | -0.073 | -0.3105 | No |
| 65 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 11337 | -0.082 | -0.3249 | Yes |
| 66 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 11457 | -0.085 | -0.3212 | Yes |
| 67 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 11671 | -0.091 | -0.3237 | Yes |
| 68 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11823 | -0.096 | -0.3207 | Yes |
| 69 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 11934 | -0.100 | -0.3140 | Yes |
| 70 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 11995 | -0.103 | -0.3032 | Yes |
| 71 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12141 | -0.109 | -0.2979 | Yes |
| 72 | HTF9C | HTF9C Entrez, Source | - | 12171 | -0.110 | -0.2836 | Yes |
| 73 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12174 | -0.110 | -0.2673 | Yes |
| 74 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12210 | -0.112 | -0.2532 | Yes |
| 75 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 12279 | -0.115 | -0.2412 | Yes |
| 76 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 12427 | -0.123 | -0.2339 | Yes |
| 77 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 12451 | -0.124 | -0.2172 | Yes |
| 78 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 12470 | -0.125 | -0.1999 | Yes |
| 79 | SFMBT1 | SFMBT1 Entrez, Source | Scm-like with four mbt domains 1 | 12486 | -0.127 | -0.1820 | Yes |
| 80 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 12504 | -0.128 | -0.1642 | Yes |
| 81 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12677 | -0.140 | -0.1563 | Yes |
| 82 | DCK | DCK Entrez, Source | deoxycytidine kinase | 12784 | -0.151 | -0.1419 | Yes |
| 83 | XTP3TPA | XTP3TPA Entrez, Source | - | 12898 | -0.165 | -0.1258 | Yes |
| 84 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 12922 | -0.168 | -0.1025 | Yes |
| 85 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13096 | -0.208 | -0.0845 | Yes |
| 86 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13114 | -0.214 | -0.0538 | Yes |
| 87 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13317 | -0.475 | 0.0019 | Yes |
