Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | V$E2F_Q6_01 |
| Enrichment Score (ES) | -0.34144717 |
| Normalized Enrichment Score (NES) | -1.3158103 |
| Nominal p-value | 0.042394016 |
| FDR q-value | 0.54719085 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 145 | 0.367 | 0.0437 | No |
| 2 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 366 | 0.223 | 0.0603 | No |
| 3 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 389 | 0.213 | 0.0903 | No |
| 4 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 473 | 0.188 | 0.1121 | No |
| 5 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 559 | 0.171 | 0.1311 | No |
| 6 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 780 | 0.141 | 0.1356 | No |
| 7 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 849 | 0.134 | 0.1504 | No |
| 8 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 1001 | 0.121 | 0.1571 | No |
| 9 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 1140 | 0.113 | 0.1635 | No |
| 10 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 1338 | 0.102 | 0.1638 | No |
| 11 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 1884 | 0.077 | 0.1342 | No |
| 12 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 2181 | 0.068 | 0.1219 | No |
| 13 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 2689 | 0.055 | 0.0919 | No |
| 14 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 3272 | 0.043 | 0.0545 | No |
| 15 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 3441 | 0.040 | 0.0477 | No |
| 16 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 3452 | 0.040 | 0.0528 | No |
| 17 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 3568 | 0.037 | 0.0497 | No |
| 18 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 3593 | 0.037 | 0.0534 | No |
| 19 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 3726 | 0.035 | 0.0486 | No |
| 20 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 3800 | 0.033 | 0.0481 | No |
| 21 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 3943 | 0.031 | 0.0420 | No |
| 22 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 3967 | 0.031 | 0.0449 | No |
| 23 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 3994 | 0.030 | 0.0474 | No |
| 24 | BARHL1 | BARHL1 Entrez, Source | BarH-like 1 (Drosophila) | 4137 | 0.028 | 0.0409 | No |
| 25 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 4288 | 0.026 | 0.0334 | No |
| 26 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 4293 | 0.026 | 0.0369 | No |
| 27 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 5390 | 0.010 | -0.0443 | No |
| 28 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 5851 | 0.004 | -0.0784 | No |
| 29 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5938 | 0.003 | -0.0845 | No |
| 30 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 5939 | 0.003 | -0.0841 | No |
| 31 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 6070 | 0.001 | -0.0937 | No |
| 32 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 6398 | -0.003 | -0.1179 | No |
| 33 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 6442 | -0.004 | -0.1206 | No |
| 34 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 6695 | -0.007 | -0.1385 | No |
| 35 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 6929 | -0.010 | -0.1547 | No |
| 36 | KLHDC3 | KLHDC3 Entrez, Source | kelch domain containing 3 | 7160 | -0.013 | -0.1701 | No |
| 37 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 7262 | -0.014 | -0.1757 | No |
| 38 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 7279 | -0.014 | -0.1748 | No |
| 39 | HTR2C | HTR2C Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2C | 7488 | -0.017 | -0.1881 | No |
| 40 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 7633 | -0.019 | -0.1961 | No |
| 41 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 7651 | -0.019 | -0.1946 | No |
| 42 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 7715 | -0.020 | -0.1965 | No |
| 43 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7792 | -0.021 | -0.1991 | No |
| 44 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 7976 | -0.023 | -0.2095 | No |
| 45 | SNCB | SNCB Entrez, Source | synuclein, beta | 8013 | -0.024 | -0.2087 | No |
| 46 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8111 | -0.025 | -0.2123 | No |
| 47 | SIAHBP1 | SIAHBP1 Entrez, Source | - | 8490 | -0.031 | -0.2362 | No |
| 48 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 8535 | -0.031 | -0.2349 | No |
| 49 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 8594 | -0.032 | -0.2345 | No |
| 50 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 8808 | -0.035 | -0.2453 | No |
| 51 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 8947 | -0.037 | -0.2502 | No |
| 52 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 8997 | -0.038 | -0.2484 | No |
| 53 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 9039 | -0.038 | -0.2458 | No |
| 54 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 9219 | -0.040 | -0.2533 | No |
| 55 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 9294 | -0.042 | -0.2526 | No |
| 56 | NCL | NCL Entrez, Source | nucleolin | 9448 | -0.044 | -0.2576 | No |
| 57 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 9466 | -0.044 | -0.2523 | No |
| 58 | ACIN1 | ACIN1 Entrez, Source | apoptotic chromatin condensation inducer 1 | 9611 | -0.047 | -0.2561 | No |
| 59 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 9637 | -0.048 | -0.2509 | No |
| 60 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 9789 | -0.050 | -0.2548 | No |
| 61 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 10568 | -0.064 | -0.3041 | No |
| 62 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10688 | -0.066 | -0.3032 | No |
| 63 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10927 | -0.072 | -0.3105 | No |
| 64 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 11337 | -0.082 | -0.3291 | Yes |
| 65 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 11457 | -0.085 | -0.3254 | Yes |
| 66 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 11671 | -0.091 | -0.3279 | Yes |
| 67 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11823 | -0.096 | -0.3250 | Yes |
| 68 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 11995 | -0.103 | -0.3226 | Yes |
| 69 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12141 | -0.109 | -0.3173 | Yes |
| 70 | HTF9C | HTF9C Entrez, Source | - | 12171 | -0.110 | -0.3031 | Yes |
| 71 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12174 | -0.110 | -0.2868 | Yes |
| 72 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12210 | -0.112 | -0.2728 | Yes |
| 73 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 12214 | -0.112 | -0.2564 | Yes |
| 74 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 12279 | -0.115 | -0.2441 | Yes |
| 75 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 12427 | -0.123 | -0.2369 | Yes |
| 76 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 12470 | -0.125 | -0.2214 | Yes |
| 77 | SFMBT1 | SFMBT1 Entrez, Source | Scm-like with four mbt domains 1 | 12486 | -0.127 | -0.2037 | Yes |
| 78 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 12504 | -0.128 | -0.1859 | Yes |
| 79 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12677 | -0.140 | -0.1781 | Yes |
| 80 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 12780 | -0.150 | -0.1635 | Yes |
| 81 | DCK | DCK Entrez, Source | deoxycytidine kinase | 12784 | -0.151 | -0.1413 | Yes |
| 82 | XTP3TPA | XTP3TPA Entrez, Source | - | 12898 | -0.165 | -0.1253 | Yes |
| 83 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 12922 | -0.168 | -0.1021 | Yes |
| 84 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13096 | -0.208 | -0.0842 | Yes |
| 85 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13114 | -0.214 | -0.0536 | Yes |
| 86 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13317 | -0.475 | 0.0019 | Yes |
