Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_8d
GeneSetV$HFH1_01
Enrichment Score (ES)0.5028472
Normalized Enrichment Score (NES)1.8055837
Nominal p-value0.0
FDR q-value0.030998703
FWER p-Value0.968
Table: GSEA Results Summary



Fig 1: Enrichment plot: V$HFH1_01   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1SCN4BSCN4B
Entrez,  Source
sodium channel, voltage-gated, type IV, beta740.4810.0458Yes
2OMDOMD
Entrez,  Source
osteomodulin790.4700.0957Yes
3FSTL1FSTL1
Entrez,  Source
follistatin-like 1800.4690.1458Yes
4EGR2EGR2
Entrez,  Source
early growth response 2 (Krox-20 homolog, Drosophila)1300.3900.1838Yes
5FSTFST
Entrez,  Source
follistatin1320.3880.2252Yes
6CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 21450.3670.2635Yes
7PPP2R3APPP2R3A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha2220.3050.2903Yes
8LAMC1LAMC1
Entrez,  Source
laminin, gamma 1 (formerly LAMB2)2240.3030.3227Yes
9SLC38A2SLC38A2
Entrez,  Source
solute carrier family 38, member 23020.2480.3434Yes
10ENPEPENPEP
Entrez,  Source
glutamyl aminopeptidase (aminopeptidase A)3380.2340.3657Yes
11DPYSL2DPYSL2
Entrez,  Source
dihydropyrimidinase-like 23660.2230.3875Yes
12CRHCRH
Entrez,  Source
corticotropin releasing hormone5410.1730.3929Yes
13MAPK3MAPK3
Entrez,  Source
mitogen-activated protein kinase 36310.1600.4033Yes
14OTX2OTX2
Entrez,  Source
orthodenticle homolog 2 (Drosophila)7080.1500.4136Yes
15NCDNNCDN
Entrez,  Source
neurochondrin7740.1420.4239Yes
16LMO4LMO4
Entrez,  Source
LIM domain only 48270.1360.4345Yes
17IHPK2IHPK2
Entrez,  Source
inositol hexaphosphate kinase 28350.1360.4485Yes
18PITX2PITX2
Entrez,  Source
paired-like homeodomain transcription factor 28500.1340.4618Yes
19FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)9210.1270.4701Yes
20NR4A1NR4A1
Entrez,  Source
nuclear receptor subfamily 4, group A, member 111920.1100.4615Yes
21DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 112970.1040.4648Yes
22ING3ING3
Entrez,  Source
inhibitor of growth family, member 313980.0990.4677Yes
23EFNA5EFNA5
Entrez,  Source
ephrin-A514360.0970.4753Yes
24ATP1B4ATP1B4
Entrez,  Source
ATPase, (Na+)/K+ transporting, beta 4 polypeptide14470.0960.4848Yes
25EIF4EBP2EIF4EBP2
Entrez,  Source
eukaryotic translation initiation factor 4E binding protein 215530.0910.4866Yes
26KCNIP4KCNIP4
Entrez,  Source
Kv channel interacting protein 417050.0850.4843Yes
27SLC16A6SLC16A6
Entrez,  Source
solute carrier family 16, member 6 (monocarboxylic acid transporter 7)17750.0810.4878Yes
28LCP2LCP2
Entrez,  Source
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)18110.0800.4937Yes
29SCG3SCG3
Entrez,  Source
secretogranin III18960.0770.4955Yes
30PRKAG1PRKAG1
Entrez,  Source
protein kinase, AMP-activated, gamma 1 non-catalytic subunit19080.0760.5028Yes
31TACSTD2TACSTD2
Entrez,  Source
tumor-associated calcium signal transducer 222000.0670.4881No
32BCL11ABCL11A
Entrez,  Source
B-cell CLL/lymphoma 11A (zinc finger protein)22220.0670.4936No
33LGI1LGI1
Entrez,  Source
leucine-rich, glioma inactivated 123650.0630.4896No
34HRHR
Entrez,  Source
hairless homolog (mouse)27510.0540.4663No
35NFIBNFIB
Entrez,  Source
nuclear factor I/B30570.0470.4483No
36NRP1NRP1
Entrez,  Source
neuropilin 133040.0420.4343No
37SUMO1SUMO1
Entrez,  Source
SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)33470.0420.4355No
38ESM1ESM1
Entrez,  Source
endothelial cell-specific molecule 133870.0410.4369No
39PHEXPHEX
Entrez,  Source
phosphate regulating endopeptidase homolog, X-linked (hypophosphatemia, vitamin D resistant rickets)35180.0380.4312No
40NEO1NEO1
Entrez,  Source
neogenin homolog 1 (chicken)38350.0330.4109No
41IBSPIBSP
Entrez,  Source
integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II)39290.0310.4072No
42CACNA1DCACNA1D
Entrez,  Source
calcium channel, voltage-dependent, L type, alpha 1D subunit41350.0280.3947No
43NLGN3NLGN3
Entrez,  Source
neuroligin 343030.0250.3848No
44CSNK1G3CSNK1G3
Entrez,  Source
casein kinase 1, gamma 344830.0230.3737No
45INHBAINHBA
Entrez,  Source
inhibin, beta A (activin A, activin AB alpha polypeptide)45960.0210.3675No
46VAX1VAX1
Entrez,  Source
ventral anterior homeobox 147210.0190.3602No
47CYP26B1CYP26B1
Entrez,  Source
cytochrome P450, family 26, subfamily B, polypeptide 148790.0170.3502No
48FOXD3FOXD3
Entrez,  Source
forkhead box D349160.0160.3492No
49CAPN3CAPN3
Entrez,  Source
calpain 3, (p94)49550.0160.3480No
50SLU7SLU7
Entrez,  Source
-49760.0160.3482No
51MAPK10MAPK10
Entrez,  Source
mitogen-activated protein kinase 1051480.0130.3367No
52HTR1BHTR1B
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 1B52210.0120.3326No
53NCAM1NCAM1
Entrez,  Source
neural cell adhesion molecule 152490.0120.3318No
54WNT2WNT2
Entrez,  Source
wingless-type MMTV integration site family member 258710.0040.2853No
55ICKICK
Entrez,  Source
intestinal cell (MAK-like) kinase60390.0020.2729No
56NTN1NTN1
Entrez,  Source
netrin 160530.0010.2720No
57C1QTNF6C1QTNF6
Entrez,  Source
C1q and tumor necrosis factor related protein 66402-0.0030.2461No
58PPP1CBPPP1CB
Entrez,  Source
protein phosphatase 1, catalytic subunit, beta isoform6632-0.0060.2295No
59SMAD1SMAD1
Entrez,  Source
SMAD, mothers against DPP homolog 1 (Drosophila)6658-0.0070.2283No
60ITGB3BPITGB3BP
Entrez,  Source
integrin beta 3 binding protein (beta3-endonexin)6849-0.0090.2149No
61ASPAASPA
Entrez,  Source
aspartoacylase (Canavan disease)7439-0.0160.1721No
62SLIT3SLIT3
Entrez,  Source
slit homolog 3 (Drosophila)7586-0.0180.1630No
63BUB3BUB3
Entrez,  Source
BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast)7602-0.0180.1638No
64NTF3NTF3
Entrez,  Source
neurotrophin 37788-0.0210.1520No
65SECISBP2SECISBP2
Entrez,  Source
SECIS binding protein 28027-0.0240.1366No
66SLC39A8SLC39A8
Entrez,  Source
solute carrier family 39 (zinc transporter), member 88133-0.0260.1314No
67GRIK2GRIK2
Entrez,  Source
glutamate receptor, ionotropic, kainate 28215-0.0270.1281No
68TOB1TOB1
Entrez,  Source
transducer of ERBB2, 18322-0.0280.1231No
69CLDN8CLDN8
Entrez,  Source
claudin 88413-0.0300.1195No
70HSD11B1HSD11B1
Entrez,  Source
hydroxysteroid (11-beta) dehydrogenase 18552-0.0310.1125No
71OTX1OTX1
Entrez,  Source
orthodenticle homolog 1 (Drosophila)8583-0.0320.1136No
72HHEXHHEX
Entrez,  Source
homeobox, hematopoietically expressed8800-0.0350.1010No
73OTPOTP
Entrez,  Source
orthopedia homolog (Drosophila)9009-0.0380.0894No
74PPP1R10PPP1R10
Entrez,  Source
protein phosphatase 1, regulatory subunit 109190-0.0400.0801No
75SHANK2SHANK2
Entrez,  Source
SH3 and multiple ankyrin repeat domains 29249-0.0410.0801No
76ATP2A2ATP2A2
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, slow twitch 29899-0.0520.0366No
77POU3F4POU3F4
Entrez,  Source
POU domain, class 3, transcription factor 49971-0.0530.0369No
78PPP2R2BPPP2R2B
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform10110-0.0550.0324No
79SLC12A5SLC12A5
Entrez,  Source
solute carrier family 12, (potassium-chloride transporter) member 510117-0.0550.0379No
80TAF5LTAF5L
Entrez,  Source
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa10163-0.0560.0405No
81ARHGEF2ARHGEF2
Entrez,  Source
rho/rac guanine nucleotide exchange factor (GEF) 210190-0.0570.0445No
82GRB7GRB7
Entrez,  Source
growth factor receptor-bound protein 710194-0.0570.0504No
83GRIK3GRIK3
Entrez,  Source
glutamate receptor, ionotropic, kainate 310240-0.0570.0531No
84MRPS18BMRPS18B
Entrez,  Source
mitochondrial ribosomal protein S18B10423-0.0610.0458No
85PMCHPMCH
Entrez,  Source
pro-melanin-concentrating hormone11172-0.078-0.0023No
86ELF1ELF1
Entrez,  Source
E74-like factor 1 (ets domain transcription factor)11340-0.083-0.0061No
87RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 111564-0.088-0.0135No
88NR4A2NR4A2
Entrez,  Source
nuclear receptor subfamily 4, group A, member 211567-0.088-0.0043No
89PIM1PIM1
Entrez,  Source
pim-1 oncogene11624-0.0900.0011No
90CYLN2CYLN2
Entrez,  Source
cytoplasmic linker 211697-0.0920.0055No
91TIMM8ATIMM8A
Entrez,  Source
translocase of inner mitochondrial membrane 8 homolog A (yeast)11939-0.100-0.0020No
92GTF2A1GTF2A1
Entrez,  Source
general transcription factor IIA, 1, 19/37kDa12080-0.106-0.0012No
93ISG20ISG20
Entrez,  Source
interferon stimulated exonuclease gene 20kDa12100-0.1070.0088No
94EFEMP1EFEMP1
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 112182-0.1110.0145No
95CASKCASK
Entrez,  Source
calcium/calmodulin-dependent serine protein kinase (MAGUK family)12276-0.1150.0198No
96IMPDH2IMPDH2
Entrez,  Source
IMP (inosine monophosphate) dehydrogenase 212451-0.1240.0198No
97GPX1GPX1
Entrez,  Source
glutathione peroxidase 112567-0.1330.0253No
98SSBP3SSBP3
Entrez,  Source
single stranded DNA binding protein 312700-0.1420.0305No
99DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)12922-0.1680.0317No
Table: GSEA details [plain text format]



Fig 2: V$HFH1_01   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: V$HFH1_01: Random ES distribution   
Gene set null distribution of ES for V$HFH1_01