Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | V$HNF4_Q6 |
| Enrichment Score (ES) | -0.2980076 |
| Normalized Enrichment Score (NES) | -1.1913059 |
| Nominal p-value | 0.12698413 |
| FDR q-value | 0.66632104 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 32 | 0.660 | 0.0663 | No |
| 2 | ADM | ADM Entrez, Source | adrenomedullin | 34 | 0.649 | 0.1338 | No |
| 3 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 44 | 0.606 | 0.1963 | No |
| 4 | FOXO1A | FOXO1A Entrez, Source | forkhead box O1A (rhabdomyosarcoma) | 213 | 0.311 | 0.2160 | No |
| 5 | SPINT1 | SPINT1 Entrez, Source | serine peptidase inhibitor, Kunitz type 1 | 297 | 0.251 | 0.2358 | No |
| 6 | LMO3 | LMO3 Entrez, Source | LIM domain only 3 (rhombotin-like 2) | 573 | 0.169 | 0.2326 | No |
| 7 | FXC1 | FXC1 Entrez, Source | fracture callus 1 homolog (rat) | 875 | 0.132 | 0.2236 | No |
| 8 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 936 | 0.126 | 0.2322 | No |
| 9 | GLYAT | GLYAT Entrez, Source | glycine-N-acyltransferase | 1056 | 0.117 | 0.2355 | No |
| 10 | JUB | JUB Entrez, Source | jub, ajuba homolog (Xenopus laevis) | 1150 | 0.112 | 0.2401 | No |
| 11 | SLC5A2 | SLC5A2 Entrez, Source | solute carrier family 5 (sodium/glucose cotransporter), member 2 | 1571 | 0.090 | 0.2178 | No |
| 12 | KIFC3 | KIFC3 Entrez, Source | kinesin family member C3 | 1724 | 0.084 | 0.2150 | No |
| 13 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 1975 | 0.074 | 0.2038 | No |
| 14 | ASB2 | ASB2 Entrez, Source | ankyrin repeat and SOCS box-containing 2 | 2030 | 0.072 | 0.2072 | No |
| 15 | USH1C | USH1C Entrez, Source | Usher syndrome 1C (autosomal recessive, severe) | 2050 | 0.071 | 0.2132 | No |
| 16 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 2079 | 0.071 | 0.2185 | No |
| 17 | HPCA | HPCA Entrez, Source | hippocalcin | 2431 | 0.061 | 0.1983 | No |
| 18 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 2842 | 0.052 | 0.1728 | No |
| 19 | RND1 | RND1 Entrez, Source | Rho family GTPase 1 | 2956 | 0.050 | 0.1694 | No |
| 20 | SFRP2 | SFRP2 Entrez, Source | secreted frizzled-related protein 2 | 3041 | 0.048 | 0.1680 | No |
| 21 | RNF40 | RNF40 Entrez, Source | ring finger protein 40 | 3254 | 0.044 | 0.1565 | No |
| 22 | ERBB3 | ERBB3 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 3516 | 0.038 | 0.1408 | No |
| 23 | CBX7 | CBX7 Entrez, Source | chromobox homolog 7 | 3674 | 0.036 | 0.1327 | No |
| 24 | EFNB1 | EFNB1 Entrez, Source | ephrin-B1 | 3795 | 0.034 | 0.1271 | No |
| 25 | SLC7A8 | SLC7A8 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 | 4160 | 0.028 | 0.1025 | No |
| 26 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 4251 | 0.026 | 0.0984 | No |
| 27 | ZDHHC3 | ZDHHC3 Entrez, Source | zinc finger, DHHC-type containing 3 | 4396 | 0.024 | 0.0900 | No |
| 28 | NUMB | NUMB Entrez, Source | numb homolog (Drosophila) | 4620 | 0.021 | 0.0753 | No |
| 29 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 4633 | 0.021 | 0.0766 | No |
| 30 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 4662 | 0.020 | 0.0766 | No |
| 31 | RAB1A | RAB1A Entrez, Source | RAB1A, member RAS oncogene family | 4681 | 0.020 | 0.0773 | No |
| 32 | AGPAT1 | AGPAT1 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) | 4698 | 0.020 | 0.0781 | No |
| 33 | GBA2 | GBA2 Entrez, Source | glucosidase, beta (bile acid) 2 | 5457 | 0.009 | 0.0218 | No |
| 34 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 5505 | 0.008 | 0.0191 | No |
| 35 | CACNB2 | CACNB2 Entrez, Source | calcium channel, voltage-dependent, beta 2 subunit | 5571 | 0.007 | 0.0149 | No |
| 36 | RASSF5 | RASSF5 Entrez, Source | Ras association (RalGDS/AF-6) domain family 5 | 5586 | 0.007 | 0.0146 | No |
| 37 | SLC9A3R1 | SLC9A3R1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 5792 | 0.005 | -0.0004 | No |
| 38 | LHX1 | LHX1 Entrez, Source | LIM homeobox 1 | 6116 | 0.000 | -0.0248 | No |
| 39 | CAB39L | CAB39L Entrez, Source | calcium binding protein 39-like | 6339 | -0.002 | -0.0413 | No |
| 40 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 6529 | -0.005 | -0.0551 | No |
| 41 | TREH | TREH Entrez, Source | trehalase (brush-border membrane glycoprotein) | 6538 | -0.005 | -0.0552 | No |
| 42 | RAB3D | RAB3D Entrez, Source | RAB3D, member RAS oncogene family | 6624 | -0.006 | -0.0610 | No |
| 43 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 6663 | -0.007 | -0.0631 | No |
| 44 | NRG2 | NRG2 Entrez, Source | neuregulin 2 | 6678 | -0.007 | -0.0635 | No |
| 45 | PTPRH | PTPRH Entrez, Source | protein tyrosine phosphatase, receptor type, H | 6701 | -0.007 | -0.0644 | No |
| 46 | LRRC17 | LRRC17 Entrez, Source | leucine rich repeat containing 17 | 6786 | -0.008 | -0.0699 | No |
| 47 | ARFIP2 | ARFIP2 Entrez, Source | ADP-ribosylation factor interacting protein 2 (arfaptin 2) | 6839 | -0.009 | -0.0730 | No |
| 48 | LUZP1 | LUZP1 Entrez, Source | leucine zipper protein 1 | 7071 | -0.012 | -0.0892 | No |
| 49 | ART3 | ART3 Entrez, Source | ADP-ribosyltransferase 3 | 7126 | -0.012 | -0.0920 | No |
| 50 | FUT2 | FUT2 Entrez, Source | fucosyltransferase 2 (secretor status included) | 7149 | -0.012 | -0.0924 | No |
| 51 | PTMS | PTMS Entrez, Source | parathymosin | 7316 | -0.014 | -0.1034 | No |
| 52 | CREB3L2 | CREB3L2 Entrez, Source | cAMP responsive element binding protein 3-like 2 | 7447 | -0.016 | -0.1116 | No |
| 53 | TAGLN2 | TAGLN2 Entrez, Source | transgelin 2 | 7600 | -0.018 | -0.1212 | No |
| 54 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 7633 | -0.019 | -0.1216 | No |
| 55 | SLC25A5 | SLC25A5 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 7635 | -0.019 | -0.1198 | No |
| 56 | SLN | SLN Entrez, Source | sarcolipin | 7739 | -0.020 | -0.1255 | No |
| 57 | FUT11 | FUT11 Entrez, Source | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 7899 | -0.022 | -0.1352 | No |
| 58 | AQP3 | AQP3 Entrez, Source | aquaporin 3 (Gill blood group) | 7975 | -0.023 | -0.1385 | No |
| 59 | TCF1 | TCF1 Entrez, Source | transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor | 8123 | -0.025 | -0.1469 | No |
| 60 | FOXA1 | FOXA1 Entrez, Source | forkhead box A1 | 8131 | -0.026 | -0.1448 | No |
| 61 | ZNF403 | ZNF403 Entrez, Source | zinc finger protein 403 | 8532 | -0.031 | -0.1718 | No |
| 62 | NAV2 | NAV2 Entrez, Source | neuron navigator 2 | 8609 | -0.032 | -0.1741 | No |
| 63 | PROS1 | PROS1 Entrez, Source | protein S (alpha) | 8724 | -0.034 | -0.1792 | No |
| 64 | RARA | RARA Entrez, Source | retinoic acid receptor, alpha | 8732 | -0.034 | -0.1762 | No |
| 65 | GPX2 | GPX2 Entrez, Source | glutathione peroxidase 2 (gastrointestinal) | 8829 | -0.035 | -0.1798 | No |
| 66 | GPD1 | GPD1 Entrez, Source | glycerol-3-phosphate dehydrogenase 1 (soluble) | 8862 | -0.036 | -0.1785 | No |
| 67 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 8894 | -0.036 | -0.1771 | No |
| 68 | NOSTRIN | NOSTRIN Entrez, Source | nitric oxide synthase trafficker | 8995 | -0.037 | -0.1807 | No |
| 69 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 9243 | -0.041 | -0.1951 | No |
| 70 | JMJD1C | JMJD1C Entrez, Source | jumonji domain containing 1C | 9316 | -0.042 | -0.1962 | No |
| 71 | MAGED1 | MAGED1 Entrez, Source | melanoma antigen family D, 1 | 9421 | -0.044 | -0.1995 | No |
| 72 | SFRS15 | SFRS15 Entrez, Source | splicing factor, arginine/serine-rich 15 | 9439 | -0.044 | -0.1962 | No |
| 73 | APC | APC Entrez, Source | adenomatosis polyposis coli | 9645 | -0.048 | -0.2067 | No |
| 74 | SLC22A7 | SLC22A7 Entrez, Source | solute carrier family 22 (organic anion transporter), member 7 | 9680 | -0.048 | -0.2043 | No |
| 75 | CACNA2D3 | CACNA2D3 Entrez, Source | calcium channel, voltage-dependent, alpha 2/delta 3 subunit | 9729 | -0.049 | -0.2028 | No |
| 76 | AGXT2 | AGXT2 Entrez, Source | alanine-glyoxylate aminotransferase 2 | 10038 | -0.054 | -0.2204 | No |
| 77 | NR5A2 | NR5A2 Entrez, Source | nuclear receptor subfamily 5, group A, member 2 | 10102 | -0.055 | -0.2194 | No |
| 78 | ARHGEF2 | ARHGEF2 Entrez, Source | rho/rac guanine nucleotide exchange factor (GEF) 2 | 10190 | -0.057 | -0.2201 | No |
| 79 | GRB7 | GRB7 Entrez, Source | growth factor receptor-bound protein 7 | 10194 | -0.057 | -0.2145 | No |
| 80 | XRCC5 | XRCC5 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | 10199 | -0.057 | -0.2089 | No |
| 81 | GRIA3 | GRIA3 Entrez, Source | glutamate receptor, ionotrophic, AMPA 3 | 10426 | -0.061 | -0.2196 | No |
| 82 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 10615 | -0.065 | -0.2271 | No |
| 83 | PELO | PELO Entrez, Source | pelota homolog (Drosophila) | 10844 | -0.069 | -0.2371 | No |
| 84 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 10861 | -0.070 | -0.2310 | No |
| 85 | MRPL2 | MRPL2 Entrez, Source | mitochondrial ribosomal protein L2 | 10912 | -0.071 | -0.2274 | No |
| 86 | MOBP | MOBP Entrez, Source | myelin-associated oligodendrocyte basic protein | 11276 | -0.081 | -0.2464 | No |
| 87 | GATA4 | GATA4 Entrez, Source | GATA binding protein 4 | 11355 | -0.083 | -0.2436 | No |
| 88 | DAP3 | DAP3 Entrez, Source | death associated protein 3 | 11558 | -0.088 | -0.2497 | No |
| 89 | LCAT | LCAT Entrez, Source | lecithin-cholesterol acyltransferase | 11800 | -0.096 | -0.2580 | No |
| 90 | SP140 | SP140 Entrez, Source | SP140 nuclear body protein | 11896 | -0.099 | -0.2548 | No |
| 91 | HFE2 | HFE2 Entrez, Source | hemochromatosis type 2 (juvenile) | 12059 | -0.105 | -0.2561 | No |
| 92 | MMP16 | MMP16 Entrez, Source | matrix metallopeptidase 16 (membrane-inserted) | 12615 | -0.135 | -0.2839 | Yes |
| 93 | AGMAT | AGMAT Entrez, Source | agmatine ureohydrolase (agmatinase) | 12658 | -0.138 | -0.2727 | Yes |
| 94 | BMF | BMF Entrez, Source | Bcl2 modifying factor | 12660 | -0.138 | -0.2584 | Yes |
| 95 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 12717 | -0.143 | -0.2477 | Yes |
| 96 | SERPIND1 | SERPIND1 Entrez, Source | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 12846 | -0.158 | -0.2409 | Yes |
| 97 | DYRK1A | DYRK1A Entrez, Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 12862 | -0.160 | -0.2253 | Yes |
| 98 | PDZK1 | PDZK1 Entrez, Source | PDZ domain containing 1 | 12895 | -0.164 | -0.2106 | Yes |
| 99 | INSR | INSR Entrez, Source | insulin receptor | 12948 | -0.173 | -0.1965 | Yes |
| 100 | GAMT | GAMT Entrez, Source | guanidinoacetate N-methyltransferase | 12960 | -0.175 | -0.1792 | Yes |
| 101 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 13029 | -0.193 | -0.1642 | Yes |
| 102 | XPNPEP2 | XPNPEP2 Entrez, Source | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound | 13087 | -0.205 | -0.1471 | Yes |
| 103 | KIAA1443 | KIAA1443 Entrez, Source | KIAA1443 | 13285 | -0.355 | -0.1250 | Yes |
| 104 | NFE2 | NFE2 Entrez, Source | nuclear factor (erythroid-derived 2), 45kDa | 13286 | -0.360 | -0.0875 | Yes |
| 105 | C9 | C9 Entrez, Source | complement component 9 | 13308 | -0.433 | -0.0440 | Yes |
| 106 | PKLR | PKLR Entrez, Source | pyruvate kinase, liver and RBC | 13313 | -0.446 | 0.0022 | Yes |
