Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | V$NFMUE1_Q6 |
| Enrichment Score (ES) | -0.35025933 |
| Normalized Enrichment Score (NES) | -1.3683912 |
| Nominal p-value | 0.030534351 |
| FDR q-value | 0.49159414 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 389 | 0.213 | 0.0073 | No |
| 2 | OTX2 | OTX2 Entrez, Source | orthodenticle homolog 2 (Drosophila) | 708 | 0.150 | 0.0090 | No |
| 3 | NCDN | NCDN Entrez, Source | neurochondrin | 774 | 0.142 | 0.0285 | No |
| 4 | POU2F1 | POU2F1 Entrez, Source | POU domain, class 2, transcription factor 1 | 1475 | 0.095 | -0.0080 | No |
| 5 | BCLAF1 | BCLAF1 Entrez, Source | BCL2-associated transcription factor 1 | 1588 | 0.090 | -0.0010 | No |
| 6 | CLK1 | CLK1 Entrez, Source | CDC-like kinase 1 | 1597 | 0.089 | 0.0137 | No |
| 7 | HOXA2 | HOXA2 Entrez, Source | homeobox A2 | 1629 | 0.088 | 0.0265 | No |
| 8 | ASB2 | ASB2 Entrez, Source | ankyrin repeat and SOCS box-containing 2 | 2030 | 0.072 | 0.0087 | No |
| 9 | CD4 | CD4 Entrez, Source | CD4 molecule | 2305 | 0.064 | -0.0009 | No |
| 10 | FKRP | FKRP Entrez, Source | fukutin related protein | 2335 | 0.064 | 0.0078 | No |
| 11 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 2441 | 0.061 | 0.0104 | No |
| 12 | TIA1 | TIA1 Entrez, Source | TIA1 cytotoxic granule-associated RNA binding protein | 2850 | 0.052 | -0.0115 | No |
| 13 | APBB1 | APBB1 Entrez, Source | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 2929 | 0.050 | -0.0088 | No |
| 14 | WASL | WASL Entrez, Source | Wiskott-Aldrich syndrome-like | 3088 | 0.047 | -0.0127 | No |
| 15 | UQCRH | UQCRH Entrez, Source | ubiquinol-cytochrome c reductase hinge protein | 3467 | 0.039 | -0.0345 | No |
| 16 | DZIP1 | DZIP1 Entrez, Source | DAZ interacting protein 1 | 3642 | 0.036 | -0.0414 | No |
| 17 | REST | REST Entrez, Source | RE1-silencing transcription factor | 3737 | 0.035 | -0.0425 | No |
| 18 | RAD23A | RAD23A Entrez, Source | RAD23 homolog A (S. cerevisiae) | 3908 | 0.032 | -0.0499 | No |
| 19 | PIGL | PIGL Entrez, Source | phosphatidylinositol glycan anchor biosynthesis, class L | 3935 | 0.031 | -0.0465 | No |
| 20 | DGCR2 | DGCR2 Entrez, Source | DiGeorge syndrome critical region gene 2 | 4039 | 0.030 | -0.0491 | No |
| 21 | ENSA | ENSA Entrez, Source | endosulfine alpha | 4072 | 0.029 | -0.0466 | No |
| 22 | EIF5 | EIF5 Entrez, Source | eukaryotic translation initiation factor 5 | 4315 | 0.025 | -0.0605 | No |
| 23 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 4662 | 0.020 | -0.0832 | No |
| 24 | RAB1A | RAB1A Entrez, Source | RAB1A, member RAS oncogene family | 4681 | 0.020 | -0.0811 | No |
| 25 | SLC35A4 | SLC35A4 Entrez, Source | solute carrier family 35, member A4 | 4819 | 0.018 | -0.0884 | No |
| 26 | ARF1 | ARF1 Entrez, Source | ADP-ribosylation factor 1 | 4845 | 0.018 | -0.0872 | No |
| 27 | ZFP37 | ZFP37 Entrez, Source | zinc finger protein 37 homolog (mouse) | 5275 | 0.011 | -0.1177 | No |
| 28 | APBB3 | APBB3 Entrez, Source | amyloid beta (A4) precursor protein-binding, family B, member 3 | 5363 | 0.010 | -0.1225 | No |
| 29 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 5410 | 0.010 | -0.1243 | No |
| 30 | ZFP91 | ZFP91 Entrez, Source | zinc finger protein 91 homolog (mouse) | 5687 | 0.006 | -0.1441 | No |
| 31 | MAEA | MAEA Entrez, Source | macrophage erythroblast attacher | 5897 | 0.003 | -0.1593 | No |
| 32 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 6128 | 0.000 | -0.1766 | No |
| 33 | USP48 | USP48 Entrez, Source | ubiquitin specific peptidase 48 | 6155 | -0.000 | -0.1786 | No |
| 34 | DEAF1 | DEAF1 Entrez, Source | deformed epidermal autoregulatory factor 1 (Drosophila) | 6302 | -0.002 | -0.1893 | No |
| 35 | ATP6V0C | ATP6V0C Entrez, Source | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | 6333 | -0.002 | -0.1911 | No |
| 36 | NFYC | NFYC Entrez, Source | nuclear transcription factor Y, gamma | 6397 | -0.003 | -0.1954 | No |
| 37 | MARK3 | MARK3 Entrez, Source | MAP/microtubule affinity-regulating kinase 3 | 6493 | -0.004 | -0.2018 | No |
| 38 | NFYA | NFYA Entrez, Source | nuclear transcription factor Y, alpha | 6517 | -0.005 | -0.2027 | No |
| 39 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 6529 | -0.005 | -0.2028 | No |
| 40 | DNAJC7 | DNAJC7 Entrez, Source | DnaJ (Hsp40) homolog, subfamily C, member 7 | 6595 | -0.006 | -0.2067 | No |
| 41 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 6696 | -0.007 | -0.2130 | No |
| 42 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 6720 | -0.007 | -0.2135 | No |
| 43 | NEUROD2 | NEUROD2 Entrez, Source | neurogenic differentiation 2 | 6765 | -0.008 | -0.2155 | No |
| 44 | FASTK | FASTK Entrez, Source | Fas-activated serine/threonine kinase | 7022 | -0.011 | -0.2329 | No |
| 45 | TCF4 | TCF4 Entrez, Source | transcription factor 4 | 7176 | -0.013 | -0.2423 | No |
| 46 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 7440 | -0.016 | -0.2594 | No |
| 47 | ATP5F1 | ATP5F1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 | 7449 | -0.016 | -0.2572 | No |
| 48 | VDAC2 | VDAC2 Entrez, Source | voltage-dependent anion channel 2 | 7498 | -0.017 | -0.2580 | No |
| 49 | USF1 | USF1 Entrez, Source | upstream transcription factor 1 | 7507 | -0.017 | -0.2557 | No |
| 50 | EEF1A1 | EEF1A1 Entrez, Source | eukaryotic translation elongation factor 1 alpha 1 | 7536 | -0.017 | -0.2549 | No |
| 51 | RFX3 | RFX3 Entrez, Source | regulatory factor X, 3 (influences HLA class II expression) | 7612 | -0.018 | -0.2574 | No |
| 52 | ADK | ADK Entrez, Source | adenosine kinase | 7944 | -0.023 | -0.2785 | No |
| 53 | PIAS3 | PIAS3 Entrez, Source | protein inhibitor of activated STAT, 3 | 7948 | -0.023 | -0.2748 | No |
| 54 | AP3D1 | AP3D1 Entrez, Source | adaptor-related protein complex 3, delta 1 subunit | 8383 | -0.029 | -0.3026 | No |
| 55 | EIF4G2 | EIF4G2 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 2 | 8447 | -0.030 | -0.3022 | No |
| 56 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 8524 | -0.031 | -0.3026 | No |
| 57 | ARCN1 | ARCN1 Entrez, Source | archain 1 | 8549 | -0.031 | -0.2990 | No |
| 58 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 8663 | -0.033 | -0.3018 | No |
| 59 | ATP5H | ATP5H Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d | 8736 | -0.034 | -0.3014 | No |
| 60 | EIF3S10 | EIF3S10 Entrez, Source | eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa | 8792 | -0.035 | -0.2996 | No |
| 61 | VAMP2 | VAMP2 Entrez, Source | vesicle-associated membrane protein 2 (synaptobrevin 2) | 8795 | -0.035 | -0.2937 | No |
| 62 | PSMB5 | PSMB5 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 5 | 8833 | -0.035 | -0.2905 | No |
| 63 | UBE2D3 | UBE2D3 Entrez, Source | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 8858 | -0.036 | -0.2861 | No |
| 64 | PABPN1 | PABPN1 Entrez, Source | poly(A) binding protein, nuclear 1 | 9064 | -0.038 | -0.2950 | No |
| 65 | ATF1 | ATF1 Entrez, Source | activating transcription factor 1 | 9168 | -0.040 | -0.2959 | No |
| 66 | SNAP25 | SNAP25 Entrez, Source | synaptosomal-associated protein, 25kDa | 9178 | -0.040 | -0.2897 | No |
| 67 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 9243 | -0.041 | -0.2876 | No |
| 68 | RBM5 | RBM5 Entrez, Source | RNA binding motif protein 5 | 9487 | -0.045 | -0.2982 | No |
| 69 | NCOR1 | NCOR1 Entrez, Source | nuclear receptor co-repressor 1 | 9602 | -0.047 | -0.2987 | No |
| 70 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 9891 | -0.052 | -0.3116 | No |
| 71 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 10069 | -0.055 | -0.3155 | No |
| 72 | RALA | RALA Entrez, Source | v-ral simian leukemia viral oncogene homolog A (ras related) | 10161 | -0.056 | -0.3128 | No |
| 73 | ARNT | ARNT Entrez, Source | aryl hydrocarbon receptor nuclear translocator | 10332 | -0.059 | -0.3154 | No |
| 74 | POLK | POLK Entrez, Source | polymerase (DNA directed) kappa | 10361 | -0.059 | -0.3073 | No |
| 75 | PRPSAP1 | PRPSAP1 Entrez, Source | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 10740 | -0.067 | -0.3244 | No |
| 76 | RPL30 | RPL30 Entrez, Source | ribosomal protein L30 | 11059 | -0.075 | -0.3355 | No |
| 77 | RPL35A | RPL35A Entrez, Source | ribosomal protein L35a | 11255 | -0.080 | -0.3365 | Yes |
| 78 | RPS27 | RPS27 Entrez, Source | ribosomal protein S27 (metallopanstimulin 1) | 11258 | -0.080 | -0.3228 | Yes |
| 79 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 11368 | -0.083 | -0.3168 | Yes |
| 80 | RPAP1 | RPAP1 Entrez, Source | RNA polymerase II associated protein 1 | 11435 | -0.085 | -0.3072 | Yes |
| 81 | YY1 | YY1 Entrez, Source | YY1 transcription factor | 11474 | -0.086 | -0.2953 | Yes |
| 82 | DAP3 | DAP3 Entrez, Source | death associated protein 3 | 11558 | -0.088 | -0.2865 | Yes |
| 83 | FBXO11 | FBXO11 Entrez, Source | F-box protein 11 | 11774 | -0.094 | -0.2865 | Yes |
| 84 | RBM12 | RBM12 Entrez, Source | RNA binding motif protein 12 | 11837 | -0.097 | -0.2745 | Yes |
| 85 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 11934 | -0.100 | -0.2645 | Yes |
| 86 | ODF2 | ODF2 Entrez, Source | outer dense fiber of sperm tails 2 | 12313 | -0.117 | -0.2730 | Yes |
| 87 | PTBP2 | PTBP2 Entrez, Source | polypyrimidine tract binding protein 2 | 12364 | -0.119 | -0.2563 | Yes |
| 88 | RBM3 | RBM3 Entrez, Source | RNA binding motif (RNP1, RRM) protein 3 | 12503 | -0.128 | -0.2447 | Yes |
| 89 | CDH23 | CDH23 Entrez, Source | cadherin-like 23 | 12527 | -0.130 | -0.2241 | Yes |
| 90 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12677 | -0.140 | -0.2113 | Yes |
| 91 | GNPAT | GNPAT Entrez, Source | glyceronephosphate O-acyltransferase | 12889 | -0.163 | -0.1993 | Yes |
| 92 | MRPL38 | MRPL38 Entrez, Source | mitochondrial ribosomal protein L38 | 12955 | -0.174 | -0.1743 | Yes |
| 93 | H1F0 | H1F0 Entrez, Source | H1 histone family, member 0 | 13032 | -0.193 | -0.1469 | Yes |
| 94 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13096 | -0.208 | -0.1158 | Yes |
| 95 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 13196 | -0.252 | -0.0800 | Yes |
| 96 | CSAD | CSAD Entrez, Source | cysteine sulfinic acid decarboxylase | 13323 | -0.529 | 0.0014 | Yes |
