Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | V$SREBP1_01 |
| Enrichment Score (ES) | -0.36165085 |
| Normalized Enrichment Score (NES) | -1.3281442 |
| Nominal p-value | 0.07073171 |
| FDR q-value | 0.5446031 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 688 | 0.151 | -0.0161 | No |
| 2 | CBX6 | CBX6 Entrez, Source | chromobox homolog 6 | 704 | 0.150 | 0.0182 | No |
| 3 | DIRC2 | DIRC2 Entrez, Source | disrupted in renal carcinoma 2 | 823 | 0.137 | 0.0417 | No |
| 4 | SNAI1 | SNAI1 Entrez, Source | snail homolog 1 (Drosophila) | 1130 | 0.113 | 0.0454 | No |
| 5 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 1267 | 0.106 | 0.0602 | No |
| 6 | STX6 | STX6 Entrez, Source | syntaxin 6 | 1357 | 0.101 | 0.0773 | No |
| 7 | HOXA2 | HOXA2 Entrez, Source | homeobox A2 | 1629 | 0.088 | 0.0776 | No |
| 8 | SNX16 | SNX16 Entrez, Source | sorting nexin 16 | 2047 | 0.071 | 0.0631 | No |
| 9 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 2135 | 0.069 | 0.0728 | No |
| 10 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 2479 | 0.060 | 0.0612 | No |
| 11 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 2584 | 0.058 | 0.0670 | No |
| 12 | DAZAP2 | DAZAP2 Entrez, Source | DAZ associated protein 2 | 3109 | 0.046 | 0.0385 | No |
| 13 | BEX1 | BEX1 Entrez, Source | brain expressed, X-linked 1 | 3322 | 0.042 | 0.0325 | No |
| 14 | SOX10 | SOX10 Entrez, Source | SRY (sex determining region Y)-box 10 | 3353 | 0.041 | 0.0400 | No |
| 15 | CBARA1 | CBARA1 Entrez, Source | calcium binding atopy-related autoantigen 1 | 3840 | 0.033 | 0.0111 | No |
| 16 | GRN | GRN Entrez, Source | granulin | 3902 | 0.032 | 0.0140 | No |
| 17 | RNF146 | RNF146 Entrez, Source | ring finger protein 146 | 4005 | 0.030 | 0.0135 | No |
| 18 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 4268 | 0.026 | -0.0001 | No |
| 19 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 4293 | 0.026 | 0.0041 | No |
| 20 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 4355 | 0.025 | 0.0053 | No |
| 21 | CAMK2D | CAMK2D Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II delta | 4524 | 0.022 | -0.0021 | No |
| 22 | BLNK | BLNK Entrez, Source | B-cell linker | 4539 | 0.022 | 0.0020 | No |
| 23 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 4616 | 0.021 | 0.0012 | No |
| 24 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 4633 | 0.021 | 0.0048 | No |
| 25 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 4662 | 0.020 | 0.0075 | No |
| 26 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 4679 | 0.020 | 0.0110 | No |
| 27 | ASNA1 | ASNA1 Entrez, Source | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 4755 | 0.019 | 0.0098 | No |
| 28 | ADCY2 | ADCY2 Entrez, Source | adenylate cyclase 2 (brain) | 4922 | 0.016 | 0.0011 | No |
| 29 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 5106 | 0.014 | -0.0094 | No |
| 30 | TRPM7 | TRPM7 Entrez, Source | transient receptor potential cation channel, subfamily M, member 7 | 5253 | 0.012 | -0.0176 | No |
| 31 | SLC36A1 | SLC36A1 Entrez, Source | solute carrier family 36 (proton/amino acid symporter), member 1 | 5447 | 0.009 | -0.0300 | No |
| 32 | ZDHHC13 | ZDHHC13 Entrez, Source | zinc finger, DHHC-type containing 13 | 5460 | 0.009 | -0.0288 | No |
| 33 | PIP5K1A | PIP5K1A Entrez, Source | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 5528 | 0.008 | -0.0320 | No |
| 34 | PIAS4 | PIAS4 Entrez, Source | protein inhibitor of activated STAT, 4 | 5686 | 0.006 | -0.0425 | No |
| 35 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 5739 | 0.005 | -0.0451 | No |
| 36 | PRKCE | PRKCE Entrez, Source | protein kinase C, epsilon | 5796 | 0.005 | -0.0483 | No |
| 37 | ACCN1 | ACCN1 Entrez, Source | amiloride-sensitive cation channel 1, neuronal (degenerin) | 6187 | -0.000 | -0.0776 | No |
| 38 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 6464 | -0.004 | -0.0974 | No |
| 39 | CANX | CANX Entrez, Source | calnexin | 6492 | -0.004 | -0.0984 | No |
| 40 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 6529 | -0.005 | -0.1000 | No |
| 41 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 6869 | -0.009 | -0.1234 | No |
| 42 | ATP7A | ATP7A Entrez, Source | ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) | 6948 | -0.010 | -0.1269 | No |
| 43 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 7029 | -0.011 | -0.1303 | No |
| 44 | RAB3A | RAB3A Entrez, Source | RAB3A, member RAS oncogene family | 7105 | -0.012 | -0.1332 | No |
| 45 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 7409 | -0.015 | -0.1523 | No |
| 46 | MYST2 | MYST2 Entrez, Source | MYST histone acetyltransferase 2 | 7417 | -0.016 | -0.1492 | No |
| 47 | QTRT1 | QTRT1 Entrez, Source | queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase) | 7751 | -0.020 | -0.1695 | No |
| 48 | HK2 | HK2 Entrez, Source | hexokinase 2 | 7823 | -0.021 | -0.1699 | No |
| 49 | GGN | GGN Entrez, Source | gametogenetin | 8020 | -0.024 | -0.1790 | No |
| 50 | COMMD3 | COMMD3 Entrez, Source | COMM domain containing 3 | 8178 | -0.026 | -0.1846 | No |
| 51 | SEPT3 | SEPT3 Entrez, Source | septin 3 | 8462 | -0.030 | -0.1988 | No |
| 52 | BAX | BAX Entrez, Source | BCL2-associated X protein | 8544 | -0.031 | -0.1975 | No |
| 53 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 8876 | -0.036 | -0.2139 | No |
| 54 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 9179 | -0.040 | -0.2272 | No |
| 55 | SUPT6H | SUPT6H Entrez, Source | suppressor of Ty 6 homolog (S. cerevisiae) | 9907 | -0.052 | -0.2697 | No |
| 56 | PDCD6IP | PDCD6IP Entrez, Source | programmed cell death 6 interacting protein | 10446 | -0.061 | -0.2958 | No |
| 57 | ATP6V0D1 | ATP6V0D1 Entrez, Source | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | 10697 | -0.066 | -0.2990 | No |
| 58 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 11044 | -0.074 | -0.3075 | No |
| 59 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 11763 | -0.094 | -0.3394 | Yes |
| 60 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 11909 | -0.100 | -0.3268 | Yes |
| 61 | CUL5 | CUL5 Entrez, Source | cullin 5 | 12013 | -0.103 | -0.3101 | Yes |
| 62 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 12229 | -0.113 | -0.2997 | Yes |
| 63 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 12235 | -0.113 | -0.2734 | Yes |
| 64 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 12406 | -0.122 | -0.2575 | Yes |
| 65 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12418 | -0.122 | -0.2294 | Yes |
| 66 | HSPBAP1 | HSPBAP1 Entrez, Source | HSPB (heat shock 27kDa) associated protein 1 | 12466 | -0.125 | -0.2034 | Yes |
| 67 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12532 | -0.130 | -0.1776 | Yes |
| 68 | POLR3C | POLR3C Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide C (62kD) | 12669 | -0.139 | -0.1550 | Yes |
| 69 | SNRPA | SNRPA Entrez, Source | small nuclear ribonucleoprotein polypeptide A | 12683 | -0.140 | -0.1228 | Yes |
| 70 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 12694 | -0.141 | -0.0902 | Yes |
| 71 | TCEAL1 | TCEAL1 Entrez, Source | transcription elongation factor A (SII)-like 1 | 13220 | -0.271 | -0.0656 | Yes |
| 72 | OSGEP | OSGEP Entrez, Source | O-sialoglycoprotein endopeptidase | 13267 | -0.316 | 0.0057 | Yes |
