Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_8d
GeneSetV$SRF_Q4
Enrichment Score (ES)0.5481438
Normalized Enrichment Score (NES)2.023875
Nominal p-value0.0
FDR q-value0.0041765375
FWER p-Value0.138
Table: GSEA Results Summary



Fig 1: Enrichment plot: V$SRF_Q4   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CTGFCTGF
Entrez,  Source
connective tissue growth factor320.6600.0518Yes
2RAB30RAB30
Entrez,  Source
RAB30, member RAS oncogene family550.5640.0964Yes
3SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4560.5620.1425Yes
4EDN1EDN1
Entrez,  Source
endothelin 11130.4100.1719Yes
5EGR2EGR2
Entrez,  Source
early growth response 2 (Krox-20 homolog, Drosophila)1300.3900.2028Yes
6FSTFST
Entrez,  Source
follistatin1320.3880.2346Yes
7FOSFOS
Entrez,  Source
v-fos FBJ murine osteosarcoma viral oncogene homolog1420.3710.2643Yes
8CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 21450.3670.2943Yes
9FOXP1FOXP1
Entrez,  Source
forkhead box P11740.3430.3204Yes
10SERPINH1SERPINH1
Entrez,  Source
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)1810.3360.3475Yes
11PPP2R3APPP2R3A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha2220.3050.3695Yes
12TAGLNTAGLN
Entrez,  Source
transgelin2530.2800.3902Yes
13SGKSGK
Entrez,  Source
serum/glucocorticoid regulated kinase3300.2370.4039Yes
14TMOD1TMOD1
Entrez,  Source
tropomodulin 13700.2200.4190Yes
15CX3CL1CX3CL1
Entrez,  Source
chemokine (C-X3-C motif) ligand 13750.2180.4366Yes
16ACTG2ACTG2
Entrez,  Source
actin, gamma 2, smooth muscle, enteric3910.2120.4528Yes
17CRHCRH
Entrez,  Source
corticotropin releasing hormone5410.1730.4558Yes
18DUSP5DUSP5
Entrez,  Source
dual specificity phosphatase 55530.1720.4691Yes
19TGIFTGIF
Entrez,  Source
TGFB-induced factor (TALE family homeobox)6180.1620.4776Yes
20NR2F2NR2F2
Entrez,  Source
nuclear receptor subfamily 2, group F, member 28060.1390.4749Yes
21SDPRSDPR
Entrez,  Source
serum deprivation response (phosphatidylserine binding protein)8510.1340.4826Yes
22JUNBJUNB
Entrez,  Source
jun B proto-oncogene8660.1320.4924Yes
23TGFB1I1TGFB1I1
Entrez,  Source
transforming growth factor beta 1 induced transcript 19190.1270.4989Yes
24CALD1CALD1
Entrez,  Source
caldesmon 19200.1270.5093Yes
25NR4A1NR4A1
Entrez,  Source
nuclear receptor subfamily 4, group A, member 111920.1100.4979Yes
26DUSP2DUSP2
Entrez,  Source
dual specificity phosphatase 212080.1090.5057Yes
27NR2F1NR2F1
Entrez,  Source
nuclear receptor subfamily 2, group F, member 112340.1080.5127Yes
28ACTN1ACTN1
Entrez,  Source
actinin, alpha 112680.1060.5188Yes
29IER2IER2
Entrez,  Source
immediate early response 212950.1040.5255Yes
30MYO1BMYO1B
Entrez,  Source
myosin IB13110.1040.5328Yes
31MMP14MMP14
Entrez,  Source
matrix metallopeptidase 14 (membrane-inserted)13120.1040.5413Yes
32TNNC1TNNC1
Entrez,  Source
troponin C type 1 (slow)14260.0970.5407Yes
33PPP1R12APPP1R12A
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 12A14340.0970.5481Yes
34ATRXATRX
Entrez,  Source
alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)16060.0890.5425No
35CDKN1BCDKN1B
Entrez,  Source
cyclin-dependent kinase inhibitor 1B (p27, Kip1)16760.0860.5443No
36ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 217310.0830.5471No
37MYO1EMYO1E
Entrez,  Source
myosin IE19420.0750.5374No
38RIMS1RIMS1
Entrez,  Source
regulating synaptic membrane exocytosis 120100.0730.5383No
39TNMDTNMD
Entrez,  Source
tenomodulin24130.0620.5130No
40SORT1SORT1
Entrez,  Source
sortilin 125040.0600.5110No
41ANXA6ANXA6
Entrez,  Source
annexin A629490.0500.4816No
42MAPKAPK2MAPKAPK2
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 230450.0480.4783No
43PPAP2BPPAP2B
Entrez,  Source
phosphatidic acid phosphatase type 2B32670.0430.4651No
44EGR1EGR1
Entrez,  Source
early growth response 132740.0430.4682No
45EGR4EGR4
Entrez,  Source
early growth response 432890.0430.4707No
46GPR20GPR20
Entrez,  Source
G protein-coupled receptor 2033440.0420.4700No
47KCNJ13KCNJ13
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 1336520.0360.4497No
48KCNA1KCNA1
Entrez,  Source
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)36810.0360.4505No
49RBBP7RBBP7
Entrez,  Source
retinoblastoma binding protein 737930.0340.4449No
50IL17BIL17B
Entrez,  Source
interleukin 17B39260.0310.4375No
51CACNA1BCACNA1B
Entrez,  Source
calcium channel, voltage-dependent, L type, alpha 1B subunit40860.0290.4279No
52EGR3EGR3
Entrez,  Source
early growth response 341010.0290.4292No
53NPPANPPA
Entrez,  Source
natriuretic peptide precursor A41770.0280.4257No
54DUSP6DUSP6
Entrez,  Source
dual specificity phosphatase 642880.0260.4195No
55NLGN3NLGN3
Entrez,  Source
neuroligin 343030.0250.4206No
56MCL1MCL1
Entrez,  Source
myeloid cell leukemia sequence 1 (BCL2-related)43070.0250.4224No
57MSX1MSX1
Entrez,  Source
msh homeobox homolog 1 (Drosophila)45360.0220.4070No
58ACTBACTB
Entrez,  Source
actin, beta47140.0190.3952No
59MYH11MYH11
Entrez,  Source
myosin, heavy chain 11, smooth muscle48990.0170.3826No
60DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)50070.0150.3758No
61NCOA6NCOA6
Entrez,  Source
nuclear receptor coactivator 651960.0130.3626No
62IHPK1IHPK1
Entrez,  Source
inositol hexaphosphate kinase 153960.0100.3484No
63DLL1DLL1
Entrez,  Source
delta-like 1 (Drosophila)54030.0100.3487No
64ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle54640.0090.3449No
65MAP2K6MAP2K6
Entrez,  Source
mitogen-activated protein kinase kinase 655050.0080.3426No
66PADI2PADI2
Entrez,  Source
peptidyl arginine deiminase, type II55920.0070.3366No
67MAP1AMAP1A
Entrez,  Source
microtubule-associated protein 1A57150.0050.3279No
68FOXE3FOXE3
Entrez,  Source
forkhead box E357460.0050.3260No
69COL23A1COL23A1
Entrez,  Source
collagen, type XXIII, alpha 158700.0040.3170No
70GAB2GAB2
Entrez,  Source
GRB2-associated binding protein 258990.0030.3152No
71PLCB3PLCB3
Entrez,  Source
phospholipase C, beta 3 (phosphatidylinositol-specific)59000.0030.3155No
72RASD2RASD2
Entrez,  Source
RASD family, member 259010.0030.3157No
73TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)59260.0030.3142No
74DGKGDGKG
Entrez,  Source
diacylglycerol kinase, gamma 90kDa59340.0030.3139No
75FGFRL1FGFRL1
Entrez,  Source
fibroblast growth factor receptor-like 16158-0.0000.2970No
76MRGPRFMRGPRF
Entrez,  Source
MAS-related GPR, member F6362-0.0030.2819No
77KCNK3KCNK3
Entrez,  Source
potassium channel, subfamily K, member 36369-0.0030.2817No
78ESRRAESRRA
Entrez,  Source
estrogen-related receptor alpha6415-0.0030.2785No
79HOXA5HOXA5
Entrez,  Source
homeobox A56663-0.0070.2604No
80JPH2JPH2
Entrez,  Source
junctophilin 26878-0.0090.2450No
81VGFVGF
Entrez,  Source
VGF nerve growth factor inducible6937-0.0100.2414No
82TPM3TPM3
Entrez,  Source
tropomyosin 36977-0.0100.2393No
83GRK6GRK6
Entrez,  Source
G protein-coupled receptor kinase 67131-0.0120.2287No
84CFL1CFL1
Entrez,  Source
cofilin 1 (non-muscle)7218-0.0130.2233No
85PFN1PFN1
Entrez,  Source
profilin 17229-0.0130.2237No
86AKAP12AKAP12
Entrez,  Source
A kinase (PRKA) anchor protein (gravin) 127409-0.0150.2114No
87ASPAASPA
Entrez,  Source
aspartoacylase (Canavan disease)7439-0.0160.2105No
88MBNL1MBNL1
Entrez,  Source
muscleblind-like (Drosophila)8090-0.0250.1634No
89RHOJRHOJ
Entrez,  Source
ras homolog gene family, member J8240-0.0270.1544No
90PPARGPPARG
Entrez,  Source
peroxisome proliferative activated receptor, gamma8513-0.0310.1364No
91H2AFXH2AFX
Entrez,  Source
H2A histone family, member X8894-0.0360.1106No
92TLE3TLE3
Entrez,  Source
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)9039-0.0380.1028No
93RERERERE
Entrez,  Source
arginine-glutamic acid dipeptide (RE) repeats9139-0.0390.0986No
94CNN1CNN1
Entrez,  Source
calponin 1, basic, smooth muscle9196-0.0400.0976No
95MID1MID1
Entrez,  Source
midline 1 (Opitz/BBB syndrome)9243-0.0410.0975No
96SLC4A3SLC4A3
Entrez,  Source
solute carrier family 4, anion exchanger, member 39347-0.0420.0932No
97SRP54SRP54
Entrez,  Source
signal recognition particle 54kDa9555-0.0460.0813No
98POU3F4POU3F4
Entrez,  Source
POU domain, class 3, transcription factor 49971-0.0530.0543No
99TAF5LTAF5L
Entrez,  Source
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa10163-0.0560.0445No
100CKMCKM
Entrez,  Source
creatine kinase, muscle10448-0.0610.0280No
101DDX17DDX17
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 1710688-0.0660.0154No
102KCNMB1KCNMB1
Entrez,  Source
potassium large conductance calcium-activated channel, subfamily M, beta member 110764-0.0680.0153No
103FGF8FGF8
Entrez,  Source
fibroblast growth factor 8 (androgen-induced)10881-0.0700.0123No
104CSDACSDA
Entrez,  Source
cold shock domain protein A11295-0.081-0.0123No
105SND1SND1
Entrez,  Source
-11565-0.088-0.0254No
106NPR3NPR3
Entrez,  Source
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)11674-0.091-0.0261No
107MUS81MUS81
Entrez,  Source
MUS81 endonuclease homolog (S. cerevisiae)11829-0.097-0.0298No
108MAPK14MAPK14
Entrez,  Source
mitogen-activated protein kinase 1412051-0.105-0.0379No
109PHF12PHF12
Entrez,  Source
PHD finger protein 1212208-0.112-0.0405No
110FGF17FGF17
Entrez,  Source
fibroblast growth factor 1712498-0.128-0.0519No
111CSRP1CSRP1
Entrez,  Source
cysteine and glycine-rich protein 112583-0.134-0.0472No
112DIXDC1DIXDC1
Entrez,  Source
DIX domain containing 112665-0.138-0.0420No
113RARBRARB
Entrez,  Source
retinoic acid receptor, beta12717-0.143-0.0341No
114SRD5A2SRD5A2
Entrez,  Source
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)12820-0.155-0.0291No
115DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)12922-0.168-0.0230No
116STAT5BSTAT5B
Entrez,  Source
signal transducer and activator of transcription 5B13204-0.257-0.0231No
117GADD45GGADD45G
Entrez,  Source
growth arrest and DNA-damage-inducible, gamma13302-0.4080.0030No
Table: GSEA details [plain text format]



Fig 2: V$SRF_Q4   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: V$SRF_Q4: Random ES distribution   
Gene set null distribution of ES for V$SRF_Q4