Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_8d
GeneSetV$SRF_Q6
Enrichment Score (ES)0.46966207
Normalized Enrichment Score (NES)1.7532916
Nominal p-value0.0016366612
FDR q-value0.039746806
FWER p-Value0.999
Table: GSEA Results Summary



Fig 1: Enrichment plot: V$SRF_Q6   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 231.0460.0860Yes
2SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4560.5620.1283Yes
3PRELPPRELP
Entrez,  Source
proline/arginine-rich end leucine-rich repeat protein1190.4010.1567Yes
4EGR2EGR2
Entrez,  Source
early growth response 2 (Krox-20 homolog, Drosophila)1300.3900.1881Yes
5FSTFST
Entrez,  Source
follistatin1320.3880.2200Yes
6FOSFOS
Entrez,  Source
v-fos FBJ murine osteosarcoma viral oncogene homolog1420.3710.2499Yes
7CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 21450.3670.2799Yes
8FOXP1FOXP1
Entrez,  Source
forkhead box P11740.3430.3061Yes
9PPP2R3APPP2R3A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha2220.3050.3277Yes
10TAGLNTAGLN
Entrez,  Source
transgelin2530.2800.3485Yes
11CX3CL1CX3CL1
Entrez,  Source
chemokine (C-X3-C motif) ligand 13750.2180.3572Yes
12ACTG2ACTG2
Entrez,  Source
actin, gamma 2, smooth muscle, enteric3910.2120.3736Yes
13ACAA2ACAA2
Entrez,  Source
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)5280.1770.3779Yes
14DUSP5DUSP5
Entrez,  Source
dual specificity phosphatase 55530.1720.3902Yes
15COL1A1COL1A1
Entrez,  Source
collagen, type I, alpha 17380.1460.3883Yes
16MYADMMYADM
Entrez,  Source
myeloid-associated differentiation marker7400.1460.4002Yes
17NR2F2NR2F2
Entrez,  Source
nuclear receptor subfamily 2, group F, member 28060.1390.4068Yes
18SDPRSDPR
Entrez,  Source
serum deprivation response (phosphatidylserine binding protein)8510.1340.4145Yes
19JUNBJUNB
Entrez,  Source
jun B proto-oncogene8660.1320.4244Yes
20TGFB1I1TGFB1I1
Entrez,  Source
transforming growth factor beta 1 induced transcript 19190.1270.4309Yes
21CALD1CALD1
Entrez,  Source
caldesmon 19200.1270.4414Yes
22NR4A1NR4A1
Entrez,  Source
nuclear receptor subfamily 4, group A, member 111920.1100.4299Yes
23DUSP2DUSP2
Entrez,  Source
dual specificity phosphatase 212080.1090.4378Yes
24NR2F1NR2F1
Entrez,  Source
nuclear receptor subfamily 2, group F, member 112340.1080.4448Yes
25BDNFBDNF
Entrez,  Source
brain-derived neurotrophic factor12670.1060.4511Yes
26ACTN1ACTN1
Entrez,  Source
actinin, alpha 112680.1060.4598Yes
27TNNC1TNNC1
Entrez,  Source
troponin C type 1 (slow)14260.0970.4559Yes
28PPP1R12APPP1R12A
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 12A14340.0970.4633Yes
29AQP2AQP2
Entrez,  Source
aquaporin 2 (collecting duct)14560.0960.4697Yes
30CDKN1BCDKN1B
Entrez,  Source
cyclin-dependent kinase inhibitor 1B (p27, Kip1)16760.0860.4602No
31ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 217310.0830.4629No
32MYO1EMYO1E
Entrez,  Source
myosin IE19420.0750.4532No
33RIMS1RIMS1
Entrez,  Source
regulating synaptic membrane exocytosis 120100.0730.4542No
34NKX6-1NKX6-1
Entrez,  Source
NK6 transcription factor related, locus 1 (Drosophila)20240.0720.4591No
35TRDNTRDN
Entrez,  Source
triadin20770.0710.4610No
36TITF1TITF1
Entrez,  Source
thyroid transcription factor 123540.0630.4453No
37TNMDTNMD
Entrez,  Source
tenomodulin24130.0620.4460No
38GNG8GNG8
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma 828360.0520.4184No
39ANXA6ANXA6
Entrez,  Source
annexin A629490.0500.4140No
40TESTES
Entrez,  Source
testis derived transcript (3 LIM domains)30360.0480.4114No
41MAPKAPK2MAPKAPK2
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 230450.0480.4148No
42PPAP2BPPAP2B
Entrez,  Source
phosphatidic acid phosphatase type 2B32670.0430.4016No
43EGR1EGR1
Entrez,  Source
early growth response 132740.0430.4047No
44GPR20GPR20
Entrez,  Source
G protein-coupled receptor 2033440.0420.4029No
45DHHDHH
Entrez,  Source
desert hedgehog homolog (Drosophila)35330.0380.3918No
46KCNA1KCNA1
Entrez,  Source
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)36810.0360.3836No
47RBBP7RBBP7
Entrez,  Source
retinoblastoma binding protein 737930.0340.3780No
48LDHALDHA
Entrez,  Source
lactate dehydrogenase A39150.0320.3714No
49IL17BIL17B
Entrez,  Source
interleukin 17B39260.0310.3733No
50NFATC4NFATC4
Entrez,  Source
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 440510.0290.3663No
51CACNA1BCACNA1B
Entrez,  Source
calcium channel, voltage-dependent, L type, alpha 1B subunit40860.0290.3661No
52EGR3EGR3
Entrez,  Source
early growth response 341010.0290.3674No
53NPPANPPA
Entrez,  Source
natriuretic peptide precursor A41770.0280.3640No
54MSX1MSX1
Entrez,  Source
msh homeobox homolog 1 (Drosophila)45360.0220.3388No
55ATF4ATF4
Entrez,  Source
activating transcription factor 4 (tax-responsive enhancer element B67)46620.0200.3310No
56ACTBACTB
Entrez,  Source
actin, beta47140.0190.3287No
57CNTFCNTF
Entrez,  Source
ciliary neurotrophic factor47820.0180.3252No
58MYH11MYH11
Entrez,  Source
myosin, heavy chain 11, smooth muscle48990.0170.3178No
59SCN3BSCN3B
Entrez,  Source
sodium channel, voltage-gated, type III, beta50970.0140.3040No
60LSP1LSP1
Entrez,  Source
lymphocyte-specific protein 151150.0140.3039No
61ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle54640.0090.2783No
62MAP2K6MAP2K6
Entrez,  Source
mitogen-activated protein kinase kinase 655050.0080.2759No
63PADI2PADI2
Entrez,  Source
peptidyl arginine deiminase, type II55920.0070.2700No
64RAB27ARAB27A
Entrez,  Source
RAB27A, member RAS oncogene family56650.0060.2650No
65MAP1AMAP1A
Entrez,  Source
microtubule-associated protein 1A57150.0050.2618No
66FOXE3FOXE3
Entrez,  Source
forkhead box E357460.0050.2600No
67CSNK1ECSNK1E
Entrez,  Source
casein kinase 1, epsilon58230.0040.2545No
68PLCB3PLCB3
Entrez,  Source
phospholipase C, beta 3 (phosphatidylinositol-specific)59000.0030.2491No
69RASD2RASD2
Entrez,  Source
RASD family, member 259010.0030.2494No
70DGKGDGKG
Entrez,  Source
diacylglycerol kinase, gamma 90kDa59340.0030.2472No
71NNATNNAT
Entrez,  Source
neuronatin61220.0000.2331No
72FGFRL1FGFRL1
Entrez,  Source
fibroblast growth factor receptor-like 16158-0.0000.2304No
73MRGPRFMRGPRF
Entrez,  Source
MAS-related GPR, member F6362-0.0030.2153No
74KCNK3KCNK3
Entrez,  Source
potassium channel, subfamily K, member 36369-0.0030.2150No
75PICALMPICALM
Entrez,  Source
phosphatidylinositol binding clathrin assembly protein6529-0.0050.2034No
76PDLIM3PDLIM3
Entrez,  Source
PDZ and LIM domain 36654-0.0060.1945No
77HOXA5HOXA5
Entrez,  Source
homeobox A56663-0.0070.1945No
78JPH2JPH2
Entrez,  Source
junctophilin 26878-0.0090.1790No
79TPM3TPM3
Entrez,  Source
tropomyosin 36977-0.0100.1725No
80RAP1ARAP1A
Entrez,  Source
RAP1A, member of RAS oncogene family7119-0.0120.1628No
81GRK6GRK6
Entrez,  Source
G protein-coupled receptor kinase 67131-0.0120.1630No
82CFL1CFL1
Entrez,  Source
cofilin 1 (non-muscle)7218-0.0130.1576No
83PFN1PFN1
Entrez,  Source
profilin 17229-0.0130.1579No
84CTDSP1CTDSP1
Entrez,  Source
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 17334-0.0150.1513No
85TCF8TCF8
Entrez,  Source
transcription factor 8 (represses interleukin 2 expression)8084-0.0250.0966No
86MBNL1MBNL1
Entrez,  Source
muscleblind-like (Drosophila)8090-0.0250.0983No
87RHOJRHOJ
Entrez,  Source
ras homolog gene family, member J8240-0.0270.0893No
88FOSL1FOSL1
Entrez,  Source
FOS-like antigen 18279-0.0280.0887No
89PPARGPPARG
Entrez,  Source
peroxisome proliferative activated receptor, gamma8513-0.0310.0736No
90UBE2D3UBE2D3
Entrez,  Source
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)8858-0.0360.0505No
91H2AFXH2AFX
Entrez,  Source
H2A histone family, member X8894-0.0360.0508No
92TLE3TLE3
Entrez,  Source
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)9039-0.0380.0431No
93RERERERE
Entrez,  Source
arginine-glutamic acid dipeptide (RE) repeats9139-0.0390.0388No
94CNN1CNN1
Entrez,  Source
calponin 1, basic, smooth muscle9196-0.0400.0379No
95SLC4A3SLC4A3
Entrez,  Source
solute carrier family 4, anion exchanger, member 39347-0.0420.0301No
96ITGA7ITGA7
Entrez,  Source
integrin, alpha 79373-0.0430.0317No
97ATP1A2ATP1A2
Entrez,  Source
ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide9475-0.0450.0277No
98ACTR3ACTR3
Entrez,  Source
ARP3 actin-related protein 3 homolog (yeast)9733-0.0490.0123No
99MATR3MATR3
Entrez,  Source
matrin 39874-0.0510.0060No
100POU3F4POU3F4
Entrez,  Source
POU domain, class 3, transcription factor 49971-0.0530.0031No
101PDLIM4PDLIM4
Entrez,  Source
PDZ and LIM domain 410146-0.056-0.0055No
102IGF1IGF1
Entrez,  Source
insulin-like growth factor 1 (somatomedin C)10373-0.060-0.0176No
103HOXA1HOXA1
Entrez,  Source
homeobox A110402-0.060-0.0148No
104SYNCRIPSYNCRIP
Entrez,  Source
synaptotagmin binding, cytoplasmic RNA interacting protein10434-0.061-0.0121No
105CKMCKM
Entrez,  Source
creatine kinase, muscle10448-0.061-0.0081No
106WNT5AWNT5A
Entrez,  Source
wingless-type MMTV integration site family, member 5A10507-0.062-0.0073No
107PRKAB2PRKAB2
Entrez,  Source
protein kinase, AMP-activated, beta 2 non-catalytic subunit10625-0.065-0.0108No
108PLNPLN
Entrez,  Source
phospholamban10671-0.066-0.0088No
109KCNMB1KCNMB1
Entrez,  Source
potassium large conductance calcium-activated channel, subfamily M, beta member 110764-0.068-0.0102No
110FGF8FGF8
Entrez,  Source
fibroblast growth factor 8 (androgen-induced)10881-0.070-0.0132No
111PDLIM7PDLIM7
Entrez,  Source
PDZ and LIM domain 7 (enigma)11377-0.083-0.0438No
112EPHB1EPHB1
Entrez,  Source
EPH receptor B111671-0.091-0.0585No
113NPR3NPR3
Entrez,  Source
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)11674-0.091-0.0511No
114MUS81MUS81
Entrez,  Source
MUS81 endonuclease homolog (S. cerevisiae)11829-0.097-0.0548No
115PHF12PHF12
Entrez,  Source
PHD finger protein 1212208-0.112-0.0742No
116SIPA1SIPA1
Entrez,  Source
signal-induced proliferation-associated gene 112263-0.115-0.0688No
117CABP1CABP1
Entrez,  Source
calcium binding protein 1 (calbrain)12456-0.124-0.0732No
118DIXDC1DIXDC1
Entrez,  Source
DIX domain containing 112665-0.138-0.0775No
119RARBRARB
Entrez,  Source
retinoic acid receptor, beta12717-0.143-0.0696No
120SRD5A2SRD5A2
Entrez,  Source
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)12820-0.155-0.0645No
121DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)12922-0.168-0.0584No
122SLC7A1SLC7A1
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 113051-0.198-0.0518No
123KIF1BKIF1B
Entrez,  Source
kinesin family member 1B13158-0.228-0.0410No
124STAT5BSTAT5B
Entrez,  Source
signal transducer and activator of transcription 5B13204-0.257-0.0233No
125GADD45GGADD45G
Entrez,  Source
growth arrest and DNA-damage-inducible, gamma13302-0.4080.0030No
Table: GSEA details [plain text format]



Fig 2: V$SRF_Q6   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: V$SRF_Q6: Random ES distribution   
Gene set null distribution of ES for V$SRF_Q6