Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | V$TEF1_Q6 |
| Enrichment Score (ES) | 0.5239235 |
| Normalized Enrichment Score (NES) | 1.8661102 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.021424197 |
| FWER p-Value | 0.796 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 11 | 0.815 | 0.0833 | Yes |
| 2 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 14 | 0.770 | 0.1626 | Yes |
| 3 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 30 | 0.665 | 0.2301 | Yes |
| 4 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 55 | 0.564 | 0.2864 | Yes |
| 5 | ANKRD1 | ANKRD1 Entrez, Source | ankyrin repeat domain 1 (cardiac muscle) | 63 | 0.532 | 0.3407 | Yes |
| 6 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 130 | 0.390 | 0.3760 | Yes |
| 7 | CRYAB | CRYAB Entrez, Source | crystallin, alpha B | 141 | 0.371 | 0.4136 | Yes |
| 8 | ANXA8 | ANXA8 Entrez, Source | annexin A8 | 177 | 0.340 | 0.4460 | Yes |
| 9 | LAMC1 | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 224 | 0.303 | 0.4738 | Yes |
| 10 | PEA15 | PEA15 Entrez, Source | phosphoprotein enriched in astrocytes 15 | 252 | 0.281 | 0.5008 | Yes |
| 11 | PRKAA2 | PRKAA2 Entrez, Source | protein kinase, AMP-activated, alpha 2 catalytic subunit | 365 | 0.224 | 0.5154 | Yes |
| 12 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 559 | 0.171 | 0.5185 | Yes |
| 13 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 694 | 0.151 | 0.5239 | Yes |
| 14 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 1267 | 0.106 | 0.4917 | No |
| 15 | PBXIP1 | PBXIP1 Entrez, Source | pre-B-cell leukemia transcription factor interacting protein 1 | 1318 | 0.103 | 0.4985 | No |
| 16 | NPPB | NPPB Entrez, Source | natriuretic peptide precursor B | 2084 | 0.070 | 0.4480 | No |
| 17 | SLC17A6 | SLC17A6 Entrez, Source | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 | 2167 | 0.068 | 0.4489 | No |
| 18 | JAM3 | JAM3 Entrez, Source | junctional adhesion molecule 3 | 2315 | 0.064 | 0.4444 | No |
| 19 | NES | NES Entrez, Source | nestin | 2342 | 0.063 | 0.4490 | No |
| 20 | DAB1 | DAB1 Entrez, Source | disabled homolog 1 (Drosophila) | 2694 | 0.055 | 0.4282 | No |
| 21 | MCAM | MCAM Entrez, Source | melanoma cell adhesion molecule | 2824 | 0.052 | 0.4238 | No |
| 22 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 3045 | 0.048 | 0.4121 | No |
| 23 | FOLR1 | FOLR1 Entrez, Source | folate receptor 1 (adult) | 3240 | 0.044 | 0.4020 | No |
| 24 | HSPB2 | HSPB2 Entrez, Source | heat shock 27kDa protein 2 | 3285 | 0.043 | 0.4031 | No |
| 25 | MPZ | MPZ Entrez, Source | myelin protein zero (Charcot-Marie-Tooth neuropathy 1B) | 3459 | 0.039 | 0.3941 | No |
| 26 | SLC6A9 | SLC6A9 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | 3495 | 0.039 | 0.3955 | No |
| 27 | SLC39A13 | SLC39A13 Entrez, Source | solute carrier family 39 (zinc transporter), member 13 | 4119 | 0.028 | 0.3514 | No |
| 28 | SCN2B | SCN2B Entrez, Source | sodium channel, voltage-gated, type II, beta | 4134 | 0.028 | 0.3532 | No |
| 29 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 4182 | 0.027 | 0.3525 | No |
| 30 | ADIPOR1 | ADIPOR1 Entrez, Source | adiponectin receptor 1 | 4207 | 0.027 | 0.3535 | No |
| 31 | CNNM2 | CNNM2 Entrez, Source | cyclin M2 | 4503 | 0.022 | 0.3335 | No |
| 32 | VAX1 | VAX1 Entrez, Source | ventral anterior homeobox 1 | 4721 | 0.019 | 0.3191 | No |
| 33 | CD2 | CD2 Entrez, Source | CD2 molecule | 4735 | 0.019 | 0.3201 | No |
| 34 | DNM3 | DNM3 Entrez, Source | dynamin 3 | 4784 | 0.018 | 0.3184 | No |
| 35 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 4788 | 0.018 | 0.3201 | No |
| 36 | PRRX1 | PRRX1 Entrez, Source | paired related homeobox 1 | 5189 | 0.013 | 0.2912 | No |
| 37 | SCNN1A | SCNN1A Entrez, Source | sodium channel, nonvoltage-gated 1 alpha | 5333 | 0.011 | 0.2815 | No |
| 38 | SLC6A13 | SLC6A13 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, GABA), member 13 | 5341 | 0.011 | 0.2821 | No |
| 39 | CACNA1E | CACNA1E Entrez, Source | calcium channel, voltage-dependent, alpha 1E subunit | 5441 | 0.009 | 0.2755 | No |
| 40 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 5464 | 0.009 | 0.2748 | No |
| 41 | PPP2R1B | PPP2R1B Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform | 5470 | 0.009 | 0.2753 | No |
| 42 | DR1 | DR1 Entrez, Source | down-regulator of transcription 1, TBP-binding (negative cofactor 2) | 5479 | 0.009 | 0.2756 | No |
| 43 | KCNIP2 | KCNIP2 Entrez, Source | Kv channel interacting protein 2 | 5580 | 0.007 | 0.2688 | No |
| 44 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 5592 | 0.007 | 0.2687 | No |
| 45 | LMNA | LMNA Entrez, Source | lamin A/C | 5805 | 0.004 | 0.2531 | No |
| 46 | FRAG1 | FRAG1 Entrez, Source | - | 5824 | 0.004 | 0.2522 | No |
| 47 | TNNI3K | TNNI3K Entrez, Source | TNNI3 interacting kinase | 5925 | 0.003 | 0.2450 | No |
| 48 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 6070 | 0.001 | 0.2342 | No |
| 49 | RNF2 | RNF2 Entrez, Source | ring finger protein 2 | 6125 | 0.000 | 0.2302 | No |
| 50 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 6239 | -0.001 | 0.2218 | No |
| 51 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 6253 | -0.001 | 0.2210 | No |
| 52 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 6323 | -0.002 | 0.2160 | No |
| 53 | MRGPRF | MRGPRF Entrez, Source | MAS-related GPR, member F | 6362 | -0.003 | 0.2134 | No |
| 54 | AVPI1 | AVPI1 Entrez, Source | arginine vasopressin-induced 1 | 6462 | -0.004 | 0.2063 | No |
| 55 | RTN3 | RTN3 Entrez, Source | reticulon 3 | 6650 | -0.006 | 0.1929 | No |
| 56 | EHD1 | EHD1 Entrez, Source | EH-domain containing 1 | 6660 | -0.007 | 0.1929 | No |
| 57 | IER5 | IER5 Entrez, Source | immediate early response 5 | 6896 | -0.009 | 0.1761 | No |
| 58 | BBOX1 | BBOX1 Entrez, Source | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 7181 | -0.013 | 0.1560 | No |
| 59 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 7269 | -0.014 | 0.1508 | No |
| 60 | PTMS | PTMS Entrez, Source | parathymosin | 7316 | -0.014 | 0.1488 | No |
| 61 | SYT8 | SYT8 Entrez, Source | synaptotagmin VIII | 7360 | -0.015 | 0.1471 | No |
| 62 | BRMS1 | BRMS1 Entrez, Source | breast cancer metastasis suppressor 1 | 7742 | -0.020 | 0.1204 | No |
| 63 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 7809 | -0.021 | 0.1176 | No |
| 64 | FGF6 | FGF6 Entrez, Source | fibroblast growth factor 6 | 7892 | -0.022 | 0.1137 | No |
| 65 | ADD3 | ADD3 Entrez, Source | adducin 3 (gamma) | 7901 | -0.022 | 0.1153 | No |
| 66 | PIAS3 | PIAS3 Entrez, Source | protein inhibitor of activated STAT, 3 | 7948 | -0.023 | 0.1142 | No |
| 67 | CACNA1S | CACNA1S Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1S subunit | 7965 | -0.023 | 0.1154 | No |
| 68 | DEDD | DEDD Entrez, Source | death effector domain containing | 8149 | -0.026 | 0.1042 | No |
| 69 | FXYD6 | FXYD6 Entrez, Source | FXYD domain containing ion transport regulator 6 | 8488 | -0.031 | 0.0819 | No |
| 70 | CNN3 | CNN3 Entrez, Source | calponin 3, acidic | 8886 | -0.036 | 0.0556 | No |
| 71 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 9014 | -0.038 | 0.0499 | No |
| 72 | SDCCAG8 | SDCCAG8 Entrez, Source | serologically defined colon cancer antigen 8 | 9304 | -0.042 | 0.0324 | No |
| 73 | JMJD1C | JMJD1C Entrez, Source | jumonji domain containing 1C | 9316 | -0.042 | 0.0359 | No |
| 74 | SYT2 | SYT2 Entrez, Source | synaptotagmin II | 9396 | -0.043 | 0.0344 | No |
| 75 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 9444 | -0.044 | 0.0354 | No |
| 76 | PTPRF | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 9495 | -0.045 | 0.0363 | No |
| 77 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 9637 | -0.048 | 0.0306 | No |
| 78 | HDGF | HDGF Entrez, Source | hepatoma-derived growth factor (high-mobility group protein 1-like) | 9943 | -0.053 | 0.0130 | No |
| 79 | CHKA | CHKA Entrez, Source | choline kinase alpha | 10678 | -0.066 | -0.0356 | No |
| 80 | MADD | MADD Entrez, Source | MAP-kinase activating death domain | 10727 | -0.067 | -0.0324 | No |
| 81 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 10954 | -0.072 | -0.0420 | No |
| 82 | IPO13 | IPO13 Entrez, Source | importin 13 | 11209 | -0.079 | -0.0530 | No |
| 83 | IL18BP | IL18BP Entrez, Source | interleukin 18 binding protein | 11509 | -0.087 | -0.0667 | No |
| 84 | PTPRJ | PTPRJ Entrez, Source | protein tyrosine phosphatase, receptor type, J | 11642 | -0.090 | -0.0674 | No |
| 85 | ELF3 | ELF3 Entrez, Source | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 12031 | -0.104 | -0.0859 | No |
| 86 | SLK | SLK Entrez, Source | STE20-like kinase (yeast) | 12099 | -0.107 | -0.0799 | No |
| 87 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12144 | -0.109 | -0.0720 | No |
| 88 | SIPA1 | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 12263 | -0.115 | -0.0691 | No |
| 89 | PRKCDBP | PRKCDBP Entrez, Source | protein kinase C, delta binding protein | 12275 | -0.115 | -0.0581 | No |
| 90 | ABCG4 | ABCG4 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 4 | 12477 | -0.126 | -0.0602 | No |
| 91 | MUC1 | MUC1 Entrez, Source | mucin 1, cell surface associated | 12515 | -0.129 | -0.0497 | No |
| 92 | NFKB2 | NFKB2 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 12596 | -0.134 | -0.0418 | No |
| 93 | NOTCH2 | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 13133 | -0.220 | -0.0596 | No |
| 94 | KIF1B | KIF1B Entrez, Source | kinesin family member 1B | 13158 | -0.228 | -0.0379 | No |
| 95 | CYP26A1 | CYP26A1 Entrez, Source | cytochrome P450, family 26, subfamily A, polypeptide 1 | 13188 | -0.246 | -0.0147 | No |
| 96 | FGFR2 | FGFR2 Entrez, Source | ffer syndrome, Jackson-Weiss syndrome) | 13200 | -0.255 | 0.0107 | No |
