Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | VEGF_MMMEC_6HRS_UP |
| Enrichment Score (ES) | 0.648519 |
| Normalized Enrichment Score (NES) | 1.9400572 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.010281971 |
| FWER p-Value | 0.419 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 3 | 1.046 | 0.1824 | Yes |
| 2 | MGP | MGP Entrez, Source | matrix Gla protein | 62 | 0.533 | 0.2710 | Yes |
| 3 | ANKRD1 | ANKRD1 Entrez, Source | ankyrin repeat domain 1 (cardiac muscle) | 63 | 0.532 | 0.3638 | Yes |
| 4 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 76 | 0.477 | 0.4462 | Yes |
| 5 | BGN | BGN Entrez, Source | biglycan | 143 | 0.369 | 0.5057 | Yes |
| 6 | RGS5 | RGS5 Entrez, Source | regulator of G-protein signalling 5 | 306 | 0.247 | 0.5366 | Yes |
| 7 | ADORA2B | ADORA2B Entrez, Source | adenosine A2b receptor | 482 | 0.186 | 0.5559 | Yes |
| 8 | SGCE | SGCE Entrez, Source | sarcoglycan, epsilon | 484 | 0.185 | 0.5881 | Yes |
| 9 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 567 | 0.170 | 0.6117 | Yes |
| 10 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 785 | 0.141 | 0.6200 | Yes |
| 11 | DIRC2 | DIRC2 Entrez, Source | disrupted in renal carcinoma 2 | 823 | 0.137 | 0.6411 | Yes |
| 12 | CCL7 | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 1159 | 0.111 | 0.6354 | Yes |
| 13 | SULT1E1 | SULT1E1 Entrez, Source | sulfotransferase family 1E, estrogen-preferring, member 1 | 1236 | 0.108 | 0.6485 | Yes |
| 14 | AQP7 | AQP7 Entrez, Source | aquaporin 7 | 1686 | 0.085 | 0.6297 | No |
| 15 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1840 | 0.078 | 0.6319 | No |
| 16 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 1925 | 0.075 | 0.6387 | No |
| 17 | FGFBP1 | FGFBP1 Entrez, Source | fibroblast growth factor binding protein 1 | 2072 | 0.071 | 0.6401 | No |
| 18 | THY1 | THY1 Entrez, Source | Thy-1 cell surface antigen | 2131 | 0.069 | 0.6478 | No |
| 19 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 2512 | 0.059 | 0.6296 | No |
| 20 | SDC4 | SDC4 Entrez, Source | syndecan 4 (amphiglycan, ryudocan) | 3195 | 0.045 | 0.5862 | No |
| 21 | ESR1 | ESR1 Entrez, Source | estrogen receptor 1 | 3749 | 0.034 | 0.5506 | No |
| 22 | MMP2 | MMP2 Entrez, Source | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 3978 | 0.031 | 0.5388 | No |
| 23 | OXTR | OXTR Entrez, Source | oxytocin receptor | 5412 | 0.010 | 0.4328 | No |
| 24 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 6771 | -0.008 | 0.3321 | No |
| 25 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 7433 | -0.016 | 0.2852 | No |
| 26 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 8471 | -0.031 | 0.2126 | No |
| 27 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 8535 | -0.031 | 0.2133 | No |
| 28 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 8687 | -0.033 | 0.2078 | No |
| 29 | PVALB | PVALB Entrez, Source | parvalbumin | 9188 | -0.040 | 0.1772 | No |
| 30 | ISL1 | ISL1 Entrez, Source | ISL1 transcription factor, LIM/homeodomain, (islet-1) | 9285 | -0.042 | 0.1773 | No |
| 31 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 10417 | -0.061 | 0.1029 | No |
| 32 | SLC6A8 | SLC6A8 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | 11625 | -0.090 | 0.0278 | No |
| 33 | GSTT1 | GSTT1 Entrez, Source | glutathione S-transferase theta 1 | 12120 | -0.108 | 0.0095 | No |
| 34 | HTR2B | HTR2B Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2B | 12292 | -0.116 | 0.0169 | No |
| 35 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 12774 | -0.149 | 0.0068 | No |
| 36 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 13085 | -0.205 | 0.0193 | No |
