Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | VEGF_MMMEC_ALL_UP |
| Enrichment Score (ES) | 0.5450831 |
| Normalized Enrichment Score (NES) | 1.8585074 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.022292452 |
| FWER p-Value | 0.827 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 3 | 1.046 | 0.1249 | Yes |
| 2 | MGP | MGP Entrez, Source | matrix Gla protein | 62 | 0.533 | 0.1843 | Yes |
| 3 | ANKRD1 | ANKRD1 Entrez, Source | ankyrin repeat domain 1 (cardiac muscle) | 63 | 0.532 | 0.2479 | Yes |
| 4 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 76 | 0.477 | 0.3041 | Yes |
| 5 | BGN | BGN Entrez, Source | biglycan | 143 | 0.369 | 0.3433 | Yes |
| 6 | FOXO1A | FOXO1A Entrez, Source | forkhead box O1A (rhabdomyosarcoma) | 213 | 0.311 | 0.3753 | Yes |
| 7 | CD9 | CD9 Entrez, Source | CD9 molecule | 299 | 0.250 | 0.3989 | Yes |
| 8 | RGS5 | RGS5 Entrez, Source | regulator of G-protein signalling 5 | 306 | 0.247 | 0.4280 | Yes |
| 9 | ADORA2B | ADORA2B Entrez, Source | adenosine A2b receptor | 482 | 0.186 | 0.4370 | Yes |
| 10 | SGCE | SGCE Entrez, Source | sarcoglycan, epsilon | 484 | 0.185 | 0.4591 | Yes |
| 11 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 561 | 0.171 | 0.4738 | Yes |
| 12 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 567 | 0.170 | 0.4938 | Yes |
| 13 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 785 | 0.141 | 0.4943 | Yes |
| 14 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 789 | 0.140 | 0.5109 | Yes |
| 15 | DIRC2 | DIRC2 Entrez, Source | disrupted in renal carcinoma 2 | 823 | 0.137 | 0.5248 | Yes |
| 16 | CCL7 | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 1159 | 0.111 | 0.5129 | Yes |
| 17 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 1192 | 0.110 | 0.5236 | Yes |
| 18 | SULT1E1 | SULT1E1 Entrez, Source | sulfotransferase family 1E, estrogen-preferring, member 1 | 1236 | 0.108 | 0.5333 | Yes |
| 19 | HEXA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 1360 | 0.101 | 0.5360 | Yes |
| 20 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 1541 | 0.092 | 0.5335 | Yes |
| 21 | TIE1 | TIE1 Entrez, Source | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 1674 | 0.086 | 0.5338 | Yes |
| 22 | AQP7 | AQP7 Entrez, Source | aquaporin 7 | 1686 | 0.085 | 0.5432 | Yes |
| 23 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1840 | 0.078 | 0.5410 | Yes |
| 24 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 1925 | 0.075 | 0.5437 | Yes |
| 25 | FGFBP1 | FGFBP1 Entrez, Source | fibroblast growth factor binding protein 1 | 2072 | 0.071 | 0.5412 | Yes |
| 26 | THY1 | THY1 Entrez, Source | Thy-1 cell surface antigen | 2131 | 0.069 | 0.5451 | Yes |
| 27 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 2512 | 0.059 | 0.5236 | No |
| 28 | SDC4 | SDC4 Entrez, Source | syndecan 4 (amphiglycan, ryudocan) | 3195 | 0.045 | 0.4775 | No |
| 29 | HCLS1 | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 3587 | 0.037 | 0.4525 | No |
| 30 | ESR1 | ESR1 Entrez, Source | estrogen receptor 1 | 3749 | 0.034 | 0.4445 | No |
| 31 | MMP2 | MMP2 Entrez, Source | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 3978 | 0.031 | 0.4310 | No |
| 32 | MMP10 | MMP10 Entrez, Source | matrix metallopeptidase 10 (stromelysin 2) | 4140 | 0.028 | 0.4222 | No |
| 33 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 4347 | 0.025 | 0.4096 | No |
| 34 | ANGPT2 | ANGPT2 Entrez, Source | angiopoietin 2 | 4649 | 0.020 | 0.3894 | No |
| 35 | KDR | KDR Entrez, Source | kinase insert domain receptor (a type III receptor tyrosine kinase) | 4694 | 0.020 | 0.3884 | No |
| 36 | OXTR | OXTR Entrez, Source | oxytocin receptor | 5412 | 0.010 | 0.3355 | No |
| 37 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 5474 | 0.009 | 0.3320 | No |
| 38 | PRKCI | PRKCI Entrez, Source | protein kinase C, iota | 6041 | 0.002 | 0.2895 | No |
| 39 | HEMGN | HEMGN Entrez, Source | hemogen | 6620 | -0.006 | 0.2467 | No |
| 40 | UBD | UBD Entrez, Source | ubiquitin D | 6622 | -0.006 | 0.2473 | No |
| 41 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 6771 | -0.008 | 0.2371 | No |
| 42 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 7062 | -0.011 | 0.2166 | No |
| 43 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 7433 | -0.016 | 0.1906 | No |
| 44 | GALNT1 | GALNT1 Entrez, Source | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) | 7850 | -0.021 | 0.1619 | No |
| 45 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 8169 | -0.026 | 0.1410 | No |
| 46 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 8471 | -0.031 | 0.1220 | No |
| 47 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 8535 | -0.031 | 0.1210 | No |
| 48 | EMR1 | EMR1 Entrez, Source | egf-like module containing, mucin-like, hormone receptor-like 1 | 8587 | -0.032 | 0.1210 | No |
| 49 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 8687 | -0.033 | 0.1175 | No |
| 50 | PVALB | PVALB Entrez, Source | parvalbumin | 9188 | -0.040 | 0.0847 | No |
| 51 | VWF | VWF Entrez, Source | von Willebrand factor | 9242 | -0.041 | 0.0856 | No |
| 52 | ISL1 | ISL1 Entrez, Source | ISL1 transcription factor, LIM/homeodomain, (islet-1) | 9285 | -0.042 | 0.0874 | No |
| 53 | PGF | PGF Entrez, Source | placental growth factor, vascular endothelial growth factor-related protein | 9350 | -0.043 | 0.0876 | No |
| 54 | PDE4B | PDE4B Entrez, Source | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) | 9537 | -0.046 | 0.0791 | No |
| 55 | MRPL19 | MRPL19 Entrez, Source | mitochondrial ribosomal protein L19 | 10051 | -0.054 | 0.0469 | No |
| 56 | RALA | RALA Entrez, Source | v-ral simian leukemia viral oncogene homolog A (ras related) | 10161 | -0.056 | 0.0455 | No |
| 57 | NAGK | NAGK Entrez, Source | N-acetylglucosamine kinase | 10368 | -0.060 | 0.0371 | No |
| 58 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 10417 | -0.061 | 0.0407 | No |
| 59 | NDUFA1 | NDUFA1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | 10602 | -0.064 | 0.0345 | No |
| 60 | RBX1 | RBX1 Entrez, Source | ring-box 1 | 10833 | -0.069 | 0.0255 | No |
| 61 | ADD2 | ADD2 Entrez, Source | adducin 2 (beta) | 11285 | -0.081 | 0.0012 | No |
| 62 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 11624 | -0.090 | -0.0136 | No |
| 63 | SLC6A8 | SLC6A8 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | 11625 | -0.090 | -0.0029 | No |
| 64 | CEACAM1 | CEACAM1 Entrez, Source | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 11634 | -0.090 | 0.0073 | No |
| 65 | GSTT1 | GSTT1 Entrez, Source | glutathione S-transferase theta 1 | 12120 | -0.108 | -0.0163 | No |
| 66 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 12182 | -0.111 | -0.0077 | No |
| 67 | HTR2B | HTR2B Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2B | 12292 | -0.116 | -0.0021 | No |
| 68 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12441 | -0.123 | 0.0015 | No |
| 69 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 12774 | -0.149 | -0.0056 | No |
| 70 | TRIM23 | TRIM23 Entrez, Source | tripartite motif-containing 23 | 13053 | -0.198 | -0.0028 | No |
| 71 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 13085 | -0.205 | 0.0194 | No |
