Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | WALKER_MM_SNP_DIFF |
| Enrichment Score (ES) | 0.6517882 |
| Normalized Enrichment Score (NES) | 1.8706253 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.020534694 |
| FWER p-Value | 0.768 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HMGCS2 | HMGCS2 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) | 66 | 0.519 | 0.1638 | Yes |
| 2 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 73 | 0.484 | 0.3210 | Yes |
| 3 | BMP2 | BMP2 Entrez, Source | bone morphogenetic protein 2 | 91 | 0.451 | 0.4666 | Yes |
| 4 | PRNP | PRNP Entrez, Source | prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) | 171 | 0.348 | 0.5739 | Yes |
| 5 | HERPUD1 | HERPUD1 Entrez, Source | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 430 | 0.201 | 0.6198 | Yes |
| 6 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 1268 | 0.106 | 0.5913 | Yes |
| 7 | ZFP36L1 | ZFP36L1 Entrez, Source | zinc finger protein 36, C3H type-like 1 | 1350 | 0.101 | 0.6182 | Yes |
| 8 | HMGB1 | HMGB1 Entrez, Source | high-mobility group box 1 | 1582 | 0.090 | 0.6301 | Yes |
| 9 | TPST2 | TPST2 Entrez, Source | tyrosylprotein sulfotransferase 2 | 2145 | 0.069 | 0.6102 | Yes |
| 10 | GABARAPL2 | GABARAPL2 Entrez, Source | GABA(A) receptor-associated protein-like 2 | 2152 | 0.069 | 0.6321 | Yes |
| 11 | PTP4A1 | PTP4A1 Entrez, Source | protein tyrosine phosphatase type IVA, member 1 | 2184 | 0.068 | 0.6518 | Yes |
| 12 | MAP1LC3B | MAP1LC3B Entrez, Source | microtubule-associated protein 1 light chain 3 beta | 3406 | 0.040 | 0.5732 | No |
| 13 | GFRA2 | GFRA2 Entrez, Source | GDNF family receptor alpha 2 | 3692 | 0.035 | 0.5633 | No |
| 14 | ESR1 | ESR1 Entrez, Source | estrogen receptor 1 | 3749 | 0.034 | 0.5703 | No |
| 15 | ASAH1 | ASAH1 Entrez, Source | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 3904 | 0.032 | 0.5691 | No |
| 16 | TM9SF2 | TM9SF2 Entrez, Source | transmembrane 9 superfamily member 2 | 4982 | 0.015 | 0.4932 | No |
| 17 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 5007 | 0.015 | 0.4963 | No |
| 18 | KCND3 | KCND3 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 3 | 5030 | 0.015 | 0.4995 | No |
| 19 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 5739 | 0.005 | 0.4481 | No |
| 20 | GABARAP | GABARAP Entrez, Source | GABA(A) receptor-associated protein | 6276 | -0.002 | 0.4083 | No |
| 21 | SENP3 | SENP3 Entrez, Source | SUMO1/sentrin/SMT3 specific peptidase 3 | 6335 | -0.002 | 0.4047 | No |
| 22 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 6950 | -0.010 | 0.3619 | No |
| 23 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 7437 | -0.016 | 0.3305 | No |
| 24 | SAP18 | SAP18 Entrez, Source | Sin3A-associated protein, 18kDa | 7954 | -0.023 | 0.2992 | No |
| 25 | CNGB1 | CNGB1 Entrez, Source | cyclic nucleotide gated channel beta 1 | 8115 | -0.025 | 0.2954 | No |
| 26 | WDR1 | WDR1 Entrez, Source | WD repeat domain 1 | 8188 | -0.026 | 0.2986 | No |
| 27 | TPT1 | TPT1 Entrez, Source | tumor protein, translationally-controlled 1 | 8697 | -0.034 | 0.2714 | No |
| 28 | TOM1 | TOM1 Entrez, Source | target of myb1 (chicken) | 9160 | -0.040 | 0.2496 | No |
| 29 | RPL13 | RPL13 Entrez, Source | ribosomal protein L13 | 11394 | -0.084 | 0.1091 | No |
| 30 | GTF3A | GTF3A Entrez, Source | general transcription factor IIIA | 12256 | -0.114 | 0.0816 | No |
