Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ZHAN_MULTIPLE_MYELOMA_VS_NORMAL_DN |
| Enrichment Score (ES) | 0.68184793 |
| Normalized Enrichment Score (NES) | 1.9598478 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.008248449 |
| FWER p-Value | 0.338 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 3 | 1.046 | 0.2283 | Yes |
| 2 | CD24 | CD24 Entrez, Source | CD24 molecule | 17 | 0.726 | 0.3860 | Yes |
| 3 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 69 | 0.494 | 0.4900 | Yes |
| 4 | APOC1 | APOC1 Entrez, Source | apolipoprotein C-I | 102 | 0.426 | 0.5808 | Yes |
| 5 | LYZ | LYZ Entrez, Source | lysozyme (renal amyloidosis) | 424 | 0.202 | 0.6008 | Yes |
| 6 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 561 | 0.171 | 0.6280 | Yes |
| 7 | PF4 | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 798 | 0.140 | 0.6408 | Yes |
| 8 | RNASE6 | RNASE6 Entrez, Source | ribonuclease, RNase A family, k6 | 868 | 0.132 | 0.6645 | Yes |
| 9 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 1183 | 0.110 | 0.6650 | Yes |
| 10 | HNMT | HNMT Entrez, Source | histamine N-methyltransferase | 1378 | 0.100 | 0.6722 | Yes |
| 11 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 1522 | 0.093 | 0.6818 | Yes |
| 12 | SMPDL3A | SMPDL3A Entrez, Source | sphingomyelin phosphodiesterase, acid-like 3A | 2687 | 0.055 | 0.6065 | No |
| 13 | CD99 | CD99 Entrez, Source | CD99 molecule | 3891 | 0.032 | 0.5232 | No |
| 14 | AIF1 | AIF1 Entrez, Source | allograft inflammatory factor 1 | 4047 | 0.030 | 0.5180 | No |
| 15 | MSX1 | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 4536 | 0.022 | 0.4861 | No |
| 16 | LCN2 | LCN2 Entrez, Source | lipocalin 2 (oncogene 24p3) | 4934 | 0.016 | 0.4598 | No |
| 17 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 5268 | 0.012 | 0.4373 | No |
| 18 | CTSH | CTSH Entrez, Source | cathepsin H | 5387 | 0.010 | 0.4306 | No |
| 19 | SYK | SYK Entrez, Source | spleen tyrosine kinase | 5570 | 0.007 | 0.4186 | No |
| 20 | ITGB2 | ITGB2 Entrez, Source | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 6196 | -0.001 | 0.3717 | No |
| 21 | LST1 | LST1 Entrez, Source | leukocyte specific transcript 1 | 6454 | -0.004 | 0.3533 | No |
| 22 | HHEX | HHEX Entrez, Source | homeobox, hematopoietically expressed | 8800 | -0.035 | 0.1848 | No |
| 23 | TOMM40 | TOMM40 Entrez, Source | translocase of outer mitochondrial membrane 40 homolog (yeast) | 9457 | -0.044 | 0.1452 | No |
| 24 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 10706 | -0.066 | 0.0659 | No |
| 25 | GP5 | GP5 Entrez, Source | glycoprotein V (platelet) | 11061 | -0.075 | 0.0556 | No |
| 26 | PYGL | PYGL Entrez, Source | phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) | 11176 | -0.078 | 0.0640 | No |
| 27 | A2M | A2M Entrez, Source | alpha-2-macroglobulin | 11335 | -0.082 | 0.0701 | No |
| 28 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 12892 | -0.163 | -0.0111 | No |
| 29 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 13085 | -0.205 | 0.0193 | No |
