Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | ZINC_ION_BINDING |
| Enrichment Score (ES) | -0.43416545 |
| Normalized Enrichment Score (NES) | -1.4977692 |
| Nominal p-value | 0.025641026 |
| FDR q-value | 0.3272854 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GDA | GDA Entrez, Source | guanine deaminase | 342 | 0.233 | 0.0301 | No |
| 2 | RASSF1 | RASSF1 Entrez, Source | Ras association (RalGDS/AF-6) domain family 1 | 588 | 0.167 | 0.0517 | No |
| 3 | CBLB | CBLB Entrez, Source | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 858 | 0.133 | 0.0634 | No |
| 4 | MEP1B | MEP1B Entrez, Source | meprin A, beta | 1097 | 0.115 | 0.0731 | No |
| 5 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 1312 | 0.104 | 0.0818 | No |
| 6 | CD4 | CD4 Entrez, Source | CD4 molecule | 2305 | 0.064 | 0.0226 | No |
| 7 | TIMM8B | TIMM8B Entrez, Source | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 2536 | 0.059 | 0.0195 | No |
| 8 | PHEX | PHEX Entrez, Source | phosphate regulating endopeptidase homolog, X-linked (hypophosphatemia, vitamin D resistant rickets) | 3518 | 0.038 | -0.0451 | No |
| 9 | RNF4 | RNF4 Entrez, Source | ring finger protein 4 | 3580 | 0.037 | -0.0408 | No |
| 10 | MSRB2 | MSRB2 Entrez, Source | methionine sulfoxide reductase B2 | 3634 | 0.036 | -0.0361 | No |
| 11 | LTA4H | LTA4H Entrez, Source | leukotriene A4 hydrolase | 3767 | 0.034 | -0.0378 | No |
| 12 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 3898 | 0.032 | -0.0399 | No |
| 13 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 3967 | 0.031 | -0.0377 | No |
| 14 | MMP2 | MMP2 Entrez, Source | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 3978 | 0.031 | -0.0311 | No |
| 15 | MMP10 | MMP10 Entrez, Source | matrix metallopeptidase 10 (stromelysin 2) | 4140 | 0.028 | -0.0365 | No |
| 16 | DUSP12 | DUSP12 Entrez, Source | dual specificity phosphatase 12 | 4176 | 0.028 | -0.0325 | No |
| 17 | CBLC | CBLC Entrez, Source | Cas-Br-M (murine) ecotropic retroviral transforming sequence c | 4320 | 0.025 | -0.0372 | No |
| 18 | LNPEP | LNPEP Entrez, Source | leucyl/cystinyl aminopeptidase | 4485 | 0.023 | -0.0441 | No |
| 19 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 4556 | 0.022 | -0.0442 | No |
| 20 | SIRT6 | SIRT6 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) | 4706 | 0.020 | -0.0507 | No |
| 21 | SLU7 | SLU7 Entrez, Source | - | 4976 | 0.016 | -0.0672 | No |
| 22 | MT3 | MT3 Entrez, Source | metallothionein 3 (growth inhibitory factor (neurotrophic)) | 5102 | 0.014 | -0.0733 | No |
| 23 | SIRT2 | SIRT2 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) | 5281 | 0.011 | -0.0840 | No |
| 24 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 5434 | 0.009 | -0.0932 | No |
| 25 | MMP8 | MMP8 Entrez, Source | matrix metallopeptidase 8 (neutrophil collagenase) | 6894 | -0.009 | -0.2007 | No |
| 26 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7962 | -0.023 | -0.2754 | No |
| 27 | S100B | S100B Entrez, Source | S100 calcium binding protein B | 8430 | -0.030 | -0.3034 | No |
| 28 | RPS29 | RPS29 Entrez, Source | ribosomal protein S29 | 8679 | -0.033 | -0.3141 | No |
| 29 | TIMM9 | TIMM9 Entrez, Source | translocase of inner mitochondrial membrane 9 homolog (yeast) | 8845 | -0.035 | -0.3180 | No |
| 30 | HDAC10 | HDAC10 Entrez, Source | histone deacetylase 10 | 9127 | -0.039 | -0.3297 | No |
| 31 | PEX12 | PEX12 Entrez, Source | peroxisomal biogenesis factor 12 | 10081 | -0.055 | -0.3883 | No |
| 32 | TIMM13 | TIMM13 Entrez, Source | translocase of inner mitochondrial membrane 13 homolog (yeast) | 10300 | -0.058 | -0.3907 | No |
| 33 | TIMM10 | TIMM10 Entrez, Source | translocase of inner mitochondrial membrane 10 homolog (yeast) | 10331 | -0.059 | -0.3788 | No |
| 34 | PIAS2 | PIAS2 Entrez, Source | protein inhibitor of activated STAT, 2 | 10336 | -0.059 | -0.3649 | No |
| 35 | RPS27 | RPS27 Entrez, Source | ribosomal protein S27 (metallopanstimulin 1) | 11258 | -0.080 | -0.4149 | Yes |
| 36 | YY1 | YY1 Entrez, Source | YY1 transcription factor | 11474 | -0.086 | -0.4105 | Yes |
| 37 | ECE2 | ECE2 Entrez, Source | endothelin converting enzyme 2 | 11609 | -0.089 | -0.3992 | Yes |
| 38 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 11628 | -0.090 | -0.3791 | Yes |
| 39 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 11995 | -0.103 | -0.3819 | Yes |
| 40 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12144 | -0.109 | -0.3669 | Yes |
| 41 | PRDM4 | PRDM4 Entrez, Source | PR domain containing 4 | 12548 | -0.132 | -0.3656 | Yes |
| 42 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 12583 | -0.134 | -0.3361 | Yes |
| 43 | MMP16 | MMP16 Entrez, Source | matrix metallopeptidase 16 (membrane-inserted) | 12615 | -0.135 | -0.3059 | Yes |
| 44 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 12642 | -0.137 | -0.2750 | Yes |
| 45 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 12718 | -0.143 | -0.2463 | Yes |
| 46 | CA2 | CA2 Entrez, Source | carbonic anhydrase II | 13081 | -0.204 | -0.2246 | Yes |
| 47 | MDM4 | MDM4 Entrez, Source | Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse) | 13231 | -0.278 | -0.1690 | Yes |
| 48 | CRIP2 | CRIP2 Entrez, Source | cysteine-rich protein 2 | 13251 | -0.301 | -0.0981 | Yes |
| 49 | APOBEC1 | APOBEC1 Entrez, Source | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 | 13309 | -0.437 | 0.0025 | Yes |
