Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | ABRAHAM_MM_VS_AL_UP |
| Enrichment Score (ES) | -0.66715145 |
| Normalized Enrichment Score (NES) | -1.7093328 |
| Nominal p-value | 0.015810277 |
| FDR q-value | 0.076160535 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IL6ST | IL6ST Entrez, Source | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 1026 | 0.189 | -0.0038 | No |
| 2 | XRCC5 | XRCC5 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | 2976 | 0.086 | -0.1170 | No |
| 3 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 3805 | 0.064 | -0.1545 | No |
| 4 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 5670 | 0.024 | -0.2850 | No |
| 5 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 6918 | -0.000 | -0.3785 | No |
| 6 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 7310 | -0.008 | -0.4046 | No |
| 7 | XRCC4 | XRCC4 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 4 | 7672 | -0.016 | -0.4256 | No |
| 8 | CDK9 | CDK9 Entrez, Source | cyclin-dependent kinase 9 (CDC2-related kinase) | 7754 | -0.018 | -0.4248 | No |
| 9 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 8700 | -0.039 | -0.4807 | No |
| 10 | PTEN | PTEN Entrez, Source | phosphatase and tensin homolog (mutated in multiple advanced cancers 1) | 9345 | -0.056 | -0.5075 | No |
| 11 | CD47 | CD47 Entrez, Source | CD47 molecule | 11473 | -0.136 | -0.6148 | Yes |
| 12 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11690 | -0.149 | -0.5734 | Yes |
| 13 | CDK5 | CDK5 Entrez, Source | cyclin-dependent kinase 5 | 12107 | -0.182 | -0.5343 | Yes |
| 14 | CDC37 | CDC37 Entrez, Source | CDC37 cell division cycle 37 homolog (S. cerevisiae) | 12294 | -0.204 | -0.4695 | Yes |
| 15 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12794 | -0.284 | -0.3971 | Yes |
| 16 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 12986 | -0.357 | -0.2736 | Yes |
| 17 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 13032 | -0.382 | -0.1293 | Yes |
| 18 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 13047 | -0.395 | 0.0221 | Yes |
