Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY |
| Enrichment Score (ES) | 0.42225847 |
| Normalized Enrichment Score (NES) | 1.5760463 |
| Nominal p-value | 0.008888889 |
| FDR q-value | 0.08023945 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SLC10A1 | SLC10A1 Entrez, Source | solute carrier family 10 (sodium/bile acid cotransporter family), member 1 | 4 | 1.246 | 0.0850 | Yes |
| 2 | ABCB11 | ABCB11 Entrez, Source | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | 46 | 0.770 | 0.1347 | Yes |
| 3 | SLC25A15 | SLC25A15 Entrez, Source | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | 113 | 0.597 | 0.1706 | Yes |
| 4 | AQP9 | AQP9 Entrez, Source | aquaporin 9 | 197 | 0.479 | 0.1971 | Yes |
| 5 | SLC7A2 | SLC7A2 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 223 | 0.456 | 0.2264 | Yes |
| 6 | SLC38A3 | SLC38A3 Entrez, Source | solute carrier family 38, member 3 | 319 | 0.384 | 0.2456 | Yes |
| 7 | SLC20A1 | SLC20A1 Entrez, Source | solute carrier family 20 (phosphate transporter), member 1 | 372 | 0.354 | 0.2659 | Yes |
| 8 | SLC6A9 | SLC6A9 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | 396 | 0.340 | 0.2874 | Yes |
| 9 | SLC22A7 | SLC22A7 Entrez, Source | solute carrier family 22 (organic anion transporter), member 7 | 437 | 0.326 | 0.3067 | Yes |
| 10 | SLC25A22 | SLC25A22 Entrez, Source | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | 488 | 0.305 | 0.3238 | Yes |
| 11 | SLC5A3 | SLC5A3 Entrez, Source | solute carrier family 5 (inositol transporters), member 3 | 565 | 0.279 | 0.3372 | Yes |
| 12 | SLC17A3 | SLC17A3 Entrez, Source | solute carrier family 17 (sodium phosphate), member 3 | 687 | 0.241 | 0.3446 | Yes |
| 13 | ABCC6 | ABCC6 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 | 775 | 0.224 | 0.3534 | Yes |
| 14 | SLC13A2 | SLC13A2 Entrez, Source | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 | 781 | 0.222 | 0.3683 | Yes |
| 15 | ABCD3 | ABCD3 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 3 | 1076 | 0.184 | 0.3587 | Yes |
| 16 | SLC6A2 | SLC6A2 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | 1098 | 0.182 | 0.3696 | Yes |
| 17 | PDPN | PDPN Entrez, Source | podoplanin | 1169 | 0.174 | 0.3762 | Yes |
| 18 | SLC22A4 | SLC22A4 Entrez, Source | solute carrier family 22 (organic cation transporter), member 4 | 1195 | 0.171 | 0.3861 | Yes |
| 19 | ATP1A3 | ATP1A3 Entrez, Source | ATPase, Na+/K+ transporting, alpha 3 polypeptide | 1543 | 0.146 | 0.3699 | Yes |
| 20 | ATP2A3 | ATP2A3 Entrez, Source | ATPase, Ca++ transporting, ubiquitous | 1600 | 0.143 | 0.3755 | Yes |
| 21 | ATP4A | ATP4A Entrez, Source | ATPase, H+/K+ exchanging, alpha polypeptide | 1654 | 0.140 | 0.3810 | Yes |
| 22 | SLC34A3 | SLC34A3 Entrez, Source | solute carrier family 34 (sodium phosphate), member 3 | 1661 | 0.139 | 0.3901 | Yes |
| 23 | SLC5A1 | SLC5A1 Entrez, Source | solute carrier family 5 (sodium/glucose cotransporter), member 1 | 1672 | 0.139 | 0.3989 | Yes |
| 24 | SLC9A3 | SLC9A3 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 3 | 1812 | 0.130 | 0.3973 | Yes |
| 25 | ATP1A4 | ATP1A4 Entrez, Source | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 1823 | 0.130 | 0.4054 | Yes |
| 26 | SLC1A2 | SLC1A2 Entrez, Source | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 1833 | 0.129 | 0.4136 | Yes |
| 27 | ATP2B3 | ATP2B3 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 3 | 1898 | 0.126 | 0.4174 | Yes |
| 28 | SLC12A3 | SLC12A3 Entrez, Source | solute carrier family 12 (sodium/chloride transporters), member 3 | 1948 | 0.124 | 0.4223 | Yes |
| 29 | SLC4A4 | SLC4A4 Entrez, Source | solute carrier family 4, sodium bicarbonate cotransporter, member 4 | 2286 | 0.111 | 0.4044 | No |
| 30 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 2317 | 0.110 | 0.4097 | No |
| 31 | ATP4B | ATP4B Entrez, Source | ATPase, H+/K+ exchanging, beta polypeptide | 2579 | 0.100 | 0.3968 | No |
| 32 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 2614 | 0.099 | 0.4010 | No |
| 33 | SLC44A1 | SLC44A1 Entrez, Source | solute carrier family 44, member 1 | 2779 | 0.092 | 0.3949 | No |
| 34 | ATP7B | ATP7B Entrez, Source | ATPase, Cu++ transporting, beta polypeptide | 2900 | 0.088 | 0.3919 | No |
| 35 | ATP2A1 | ATP2A1 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 2970 | 0.086 | 0.3926 | No |
| 36 | SLC17A5 | SLC17A5 Entrez, Source | solute carrier family 17 (anion/sugar transporter), member 5 | 3307 | 0.076 | 0.3724 | No |
| 37 | SLC7A8 | SLC7A8 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 | 3436 | 0.073 | 0.3677 | No |
| 38 | SLC18A3 | SLC18A3 Entrez, Source | solute carrier family 18 (vesicular acetylcholine), member 3 | 3741 | 0.065 | 0.3493 | No |
| 39 | ABCG2 | ABCG2 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 2 | 3807 | 0.064 | 0.3487 | No |
| 40 | ABCF1 | ABCF1 Entrez, Source | ATP-binding cassette, sub-family F (GCN20), member 1 | 4274 | 0.053 | 0.3172 | No |
| 41 | ATP1A2 | ATP1A2 Entrez, Source | ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide | 4578 | 0.047 | 0.2976 | No |
| 42 | SLC1A5 | SLC1A5 Entrez, Source | solute carrier family 1 (neutral amino acid transporter), member 5 | 4697 | 0.044 | 0.2917 | No |
| 43 | SLC6A6 | SLC6A6 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | 4874 | 0.040 | 0.2811 | No |
| 44 | SLC6A5 | SLC6A5 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, glycine), member 5 | 5177 | 0.034 | 0.2607 | No |
| 45 | SLC1A3 | SLC1A3 Entrez, Source | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 5362 | 0.031 | 0.2489 | No |
| 46 | SLC17A7 | SLC17A7 Entrez, Source | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 | 5373 | 0.031 | 0.2503 | No |
| 47 | FXYD2 | FXYD2 Entrez, Source | FXYD domain containing ion transport regulator 2 | 5862 | 0.021 | 0.2149 | No |
| 48 | SLC5A7 | SLC5A7 Entrez, Source | solute carrier family 5 (choline transporter), member 7 | 5926 | 0.020 | 0.2115 | No |
| 49 | SLC5A6 | SLC5A6 Entrez, Source | solute carrier family 5 (sodium-dependent vitamin transporter), member 6 | 5944 | 0.019 | 0.2115 | No |
| 50 | SLC12A1 | SLC12A1 Entrez, Source | solute carrier family 12 (sodium/potassium/chloride transporters), member 1 | 6129 | 0.016 | 0.1987 | No |
| 51 | ATP1B2 | ATP1B2 Entrez, Source | ATPase, Na+/K+ transporting, beta 2 polypeptide | 6325 | 0.011 | 0.1848 | No |
| 52 | SLC1A6 | SLC1A6 Entrez, Source | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 | 6674 | 0.005 | 0.1588 | No |
| 53 | SLC1A4 | SLC1A4 Entrez, Source | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 6704 | 0.004 | 0.1569 | No |
| 54 | SLC9A2 | SLC9A2 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 2 | 6862 | 0.001 | 0.1451 | No |
| 55 | ATP2B1 | ATP2B1 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 1 | 6925 | -0.000 | 0.1405 | No |
| 56 | SLC7A9 | SLC7A9 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 | 7015 | -0.002 | 0.1339 | No |
| 57 | TAPBP | TAPBP Entrez, Source | TAP binding protein (tapasin) | 7131 | -0.005 | 0.1255 | No |
| 58 | SLC7A10 | SLC7A10 Entrez, Source | solute carrier family 7, (neutral amino acid transporter, y+ system) member 10 | 7229 | -0.007 | 0.1187 | No |
| 59 | SLC5A2 | SLC5A2 Entrez, Source | solute carrier family 5 (sodium/glucose cotransporter), member 2 | 7237 | -0.007 | 0.1187 | No |
| 60 | SLC18A1 | SLC18A1 Entrez, Source | solute carrier family 18 (vesicular monoamine), member 1 | 7528 | -0.013 | 0.0977 | No |
| 61 | ATP2B4 | ATP2B4 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 4 | 7808 | -0.019 | 0.0779 | No |
| 62 | ATP6V0E1 | ATP6V0E1 Entrez, Source | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 7973 | -0.023 | 0.0671 | No |
| 63 | SLC4A3 | SLC4A3 Entrez, Source | solute carrier family 4, anion exchanger, member 3 | 7978 | -0.023 | 0.0683 | No |
| 64 | SLC1A1 | SLC1A1 Entrez, Source | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 8024 | -0.024 | 0.0666 | No |
| 65 | ATP6V0C | ATP6V0C Entrez, Source | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | 8097 | -0.025 | 0.0629 | No |
| 66 | ABCA3 | ABCA3 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 3 | 8214 | -0.028 | 0.0560 | No |
| 67 | SLC22A3 | SLC22A3 Entrez, Source | solute carrier family 22 (extraneuronal monoamine transporter), member 3 | 8310 | -0.030 | 0.0509 | No |
| 68 | ATP2C1 | ATP2C1 Entrez, Source | ATPase, Ca++ transporting, type 2C, member 1 | 8499 | -0.034 | 0.0391 | No |
| 69 | SLC3A1 | SLC3A1 Entrez, Source | 1 | 8542 | -0.036 | 0.0384 | No |
| 70 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 8548 | -0.036 | 0.0404 | No |
| 71 | ATP1B3 | ATP1B3 Entrez, Source | ATPase, Na+/K+ transporting, beta 3 polypeptide | 8756 | -0.040 | 0.0275 | No |
| 72 | SLC25A11 | SLC25A11 Entrez, Source | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 8929 | -0.044 | 0.0176 | No |
| 73 | ABCC3 | ABCC3 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 9289 | -0.054 | -0.0058 | No |
| 74 | SLC12A9 | SLC12A9 Entrez, Source | solute carrier family 12 (potassium/chloride transporters), member 9 | 9300 | -0.054 | -0.0028 | No |
| 75 | ATP1A1 | ATP1A1 Entrez, Source | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 9325 | -0.055 | -0.0009 | No |
| 76 | SLC6A3 | SLC6A3 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 9597 | -0.062 | -0.0171 | No |
| 77 | ATP2A2 | ATP2A2 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 9620 | -0.063 | -0.0144 | No |
| 78 | ATP7A | ATP7A Entrez, Source | ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) | 9722 | -0.066 | -0.0175 | No |
| 79 | SERINC1 | SERINC1 Entrez, Source | serine incorporator 1 | 9801 | -0.068 | -0.0187 | No |
| 80 | SLC9A1 | SLC9A1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) | 10314 | -0.085 | -0.0515 | No |
| 81 | SLC12A4 | SLC12A4 Entrez, Source | solute carrier family 12 (potassium/chloride transporters), member 4 | 10572 | -0.094 | -0.0645 | No |
| 82 | SLC20A2 | SLC20A2 Entrez, Source | solute carrier family 20 (phosphate transporter), member 2 | 10687 | -0.098 | -0.0664 | No |
| 83 | SLC15A2 | SLC15A2 Entrez, Source | solute carrier family 15 (H+/peptide transporter), member 2 | 11088 | -0.116 | -0.0886 | No |
| 84 | SLC12A2 | SLC12A2 Entrez, Source | solute carrier family 12 (sodium/potassium/chloride transporters), member 2 | 11116 | -0.118 | -0.0826 | No |
| 85 | ATP6V1C1 | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 11130 | -0.118 | -0.0755 | No |
| 86 | ATP6V1B2 | ATP6V1B2 Entrez, Source | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | 11244 | -0.124 | -0.0755 | No |
| 87 | ABCD4 | ABCD4 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 4 | 11330 | -0.128 | -0.0732 | No |
| 88 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 11599 | -0.144 | -0.0836 | No |
| 89 | SLC18A2 | SLC18A2 Entrez, Source | solute carrier family 18 (vesicular monoamine), member 2 | 12001 | -0.173 | -0.1020 | No |
| 90 | SLC3A2 | SLC3A2 Entrez, Source | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 12198 | -0.191 | -0.1037 | No |
| 91 | ABCC1 | ABCC1 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 12224 | -0.195 | -0.0922 | No |
| 92 | ABCC2 | ABCC2 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 12438 | -0.220 | -0.0932 | No |
| 93 | SLC6A8 | SLC6A8 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | 12677 | -0.260 | -0.0934 | No |
| 94 | SLC12A7 | SLC12A7 Entrez, Source | solute carrier family 12 (potassium/chloride transporters), member 7 | 12774 | -0.279 | -0.0815 | No |
| 95 | SLC15A1 | SLC15A1 Entrez, Source | solute carrier family 15 (oligopeptide transporter), member 1 | 12976 | -0.349 | -0.0727 | No |
| 96 | ABCG1 | ABCG1 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 1 | 13094 | -0.421 | -0.0527 | No |
| 97 | SLC10A2 | SLC10A2 Entrez, Source | solute carrier family 10 (sodium/bile acid cotransporter family), member 2 | 13314 | -1.041 | 0.0021 | No |
