Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | ACTTTAT,MIR-142-5P |
| Enrichment Score (ES) | -0.4302304 |
| Normalized Enrichment Score (NES) | -1.613589 |
| Nominal p-value | 0.0018348624 |
| FDR q-value | 0.11150242 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 192 | 0.482 | 0.0105 | No |
| 2 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 236 | 0.445 | 0.0303 | No |
| 3 | MGLL | MGLL Entrez, Source | monoglyceride lipase | 241 | 0.443 | 0.0531 | No |
| 4 | ZFP36 | ZFP36 Entrez, Source | zinc finger protein 36, C3H type, homolog (mouse) | 286 | 0.407 | 0.0708 | No |
| 5 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 299 | 0.398 | 0.0906 | No |
| 6 | BMP2 | BMP2 Entrez, Source | bone morphogenetic protein 2 | 370 | 0.355 | 0.1037 | No |
| 7 | HERPUD1 | HERPUD1 Entrez, Source | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 425 | 0.331 | 0.1168 | No |
| 8 | TMEM54 | TMEM54 Entrez, Source | transmembrane protein 54 | 454 | 0.319 | 0.1313 | No |
| 9 | SREBF1 | SREBF1 Entrez, Source | sterol regulatory element binding transcription factor 1 | 467 | 0.313 | 0.1466 | No |
| 10 | CDC37L1 | CDC37L1 Entrez, Source | CDC37 cell division cycle 37 homolog (S. cerevisiae)-like 1 | 790 | 0.221 | 0.1337 | No |
| 11 | EPAS1 | EPAS1 Entrez, Source | endothelial PAS domain protein 1 | 871 | 0.211 | 0.1386 | No |
| 12 | WWP1 | WWP1 Entrez, Source | WW domain containing E3 ubiquitin protein ligase 1 | 1206 | 0.170 | 0.1222 | No |
| 13 | BVES | BVES Entrez, Source | blood vessel epicardial substance | 1437 | 0.155 | 0.1128 | No |
| 14 | ST8SIA2 | ST8SIA2 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 | 1450 | 0.153 | 0.1199 | No |
| 15 | PAPOLB | PAPOLB Entrez, Source | poly(A) polymerase beta (testis specific) | 1497 | 0.150 | 0.1242 | No |
| 16 | GRM7 | GRM7 Entrez, Source | glutamate receptor, metabotropic 7 | 1547 | 0.146 | 0.1281 | No |
| 17 | OTX2 | OTX2 Entrez, Source | orthodenticle homolog 2 (Drosophila) | 1795 | 0.131 | 0.1162 | No |
| 18 | NTRK3 | NTRK3 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 3 | 1841 | 0.129 | 0.1195 | No |
| 19 | MYO1D | MYO1D Entrez, Source | myosin ID | 1925 | 0.125 | 0.1197 | No |
| 20 | SLC4A4 | SLC4A4 Entrez, Source | solute carrier family 4, sodium bicarbonate cotransporter, member 4 | 2286 | 0.111 | 0.0982 | No |
| 21 | TMEM23 | TMEM23 Entrez, Source | transmembrane protein 23 | 2473 | 0.104 | 0.0896 | No |
| 22 | PTPN4 | PTPN4 Entrez, Source | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | 2476 | 0.104 | 0.0948 | No |
| 23 | DDHD1 | DDHD1 Entrez, Source | DDHD domain containing 1 | 2904 | 0.088 | 0.0671 | No |
| 24 | SYT7 | SYT7 Entrez, Source | synaptotagmin VII | 2906 | 0.088 | 0.0715 | No |
| 25 | IL18BP | IL18BP Entrez, Source | interleukin 18 binding protein | 2940 | 0.087 | 0.0735 | No |
| 26 | APBB3 | APBB3 Entrez, Source | amyloid beta (A4) precursor protein-binding, family B, member 3 | 3527 | 0.070 | 0.0329 | No |
| 27 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 3802 | 0.064 | 0.0155 | No |
| 28 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 4354 | 0.052 | -0.0235 | No |
| 29 | ABCG4 | ABCG4 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 4 | 4781 | 0.042 | -0.0536 | No |
| 30 | RIC8B | RIC8B Entrez, Source | resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) | 4963 | 0.039 | -0.0653 | No |
| 31 | GAS7 | GAS7 Entrez, Source | growth arrest-specific 7 | 5073 | 0.036 | -0.0716 | No |
| 32 | HDLBP | HDLBP Entrez, Source | high density lipoprotein binding protein (vigilin) | 5095 | 0.036 | -0.0713 | No |
| 33 | GPR88 | GPR88 Entrez, Source | G protein-coupled receptor 88 | 5196 | 0.034 | -0.0771 | No |
| 34 | VPS54 | VPS54 Entrez, Source | vacuolar protein sorting 54 (S. cerevisiae) | 5255 | 0.033 | -0.0798 | No |
| 35 | SLC17A7 | SLC17A7 Entrez, Source | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 | 5373 | 0.031 | -0.0871 | No |
| 36 | MKLN1 | MKLN1 Entrez, Source | muskelin 1, intracellular mediator containing kelch motifs | 5515 | 0.027 | -0.0963 | No |
| 37 | SLC36A1 | SLC36A1 Entrez, Source | solute carrier family 36 (proton/amino acid symporter), member 1 | 5594 | 0.026 | -0.1009 | No |
| 38 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 5611 | 0.025 | -0.1008 | No |
| 39 | SLC25A27 | SLC25A27 Entrez, Source | solute carrier family 25, member 27 | 6177 | 0.015 | -0.1427 | No |
| 40 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 6222 | 0.014 | -0.1454 | No |
| 41 | TRPC4AP | TRPC4AP Entrez, Source | transient receptor potential cation channel, subfamily C, member 4 associated protein | 6369 | 0.010 | -0.1559 | No |
| 42 | LRP2 | LRP2 Entrez, Source | low density lipoprotein-related protein 2 | 6508 | 0.008 | -0.1659 | No |
| 43 | UNC84A | UNC84A Entrez, Source | unc-84 homolog A (C. elegans) | 6596 | 0.006 | -0.1722 | No |
| 44 | KCNJ3 | KCNJ3 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 3 | 6736 | 0.004 | -0.1825 | No |
| 45 | UBE2A | UBE2A Entrez, Source | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 6804 | 0.002 | -0.1875 | No |
| 46 | ATP2B1 | ATP2B1 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 1 | 6925 | -0.000 | -0.1965 | No |
| 47 | DIO2 | DIO2 Entrez, Source | deiodinase, iodothyronine, type II | 6980 | -0.002 | -0.2005 | No |
| 48 | PPM1G | PPM1G Entrez, Source | protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform | 7035 | -0.003 | -0.2045 | No |
| 49 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 7100 | -0.004 | -0.2091 | No |
| 50 | BTBD1 | BTBD1 Entrez, Source | BTB (POZ) domain containing 1 | 7103 | -0.004 | -0.2090 | No |
| 51 | CAMK2A | CAMK2A Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha | 7201 | -0.006 | -0.2161 | No |
| 52 | UBE4A | UBE4A Entrez, Source | ubiquitination factor E4A (UFD2 homolog, yeast) | 7203 | -0.006 | -0.2158 | No |
| 53 | FBXL3 | FBXL3 Entrez, Source | F-box and leucine-rich repeat protein 3 | 7232 | -0.007 | -0.2176 | No |
| 54 | TAOK2 | TAOK2 Entrez, Source | TAO kinase 2 | 7244 | -0.007 | -0.2180 | No |
| 55 | KIT | KIT Entrez, Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 7340 | -0.009 | -0.2247 | No |
| 56 | SHANK2 | SHANK2 Entrez, Source | SH3 and multiple ankyrin repeat domains 2 | 7570 | -0.014 | -0.2413 | No |
| 57 | LPHN3 | LPHN3 Entrez, Source | latrophilin 3 | 7585 | -0.014 | -0.2416 | No |
| 58 | CLCN3 | CLCN3 Entrez, Source | chloride channel 3 | 7723 | -0.017 | -0.2511 | No |
| 59 | RPS25 | RPS25 Entrez, Source | ribosomal protein S25 | 8011 | -0.024 | -0.2716 | No |
| 60 | OTUD4 | OTUD4 Entrez, Source | OTU domain containing 4 | 8435 | -0.033 | -0.3019 | No |
| 61 | TMEM49 | TMEM49 Entrez, Source | transmembrane protein 49 | 8469 | -0.034 | -0.3026 | No |
| 62 | KLF10 | KLF10 Entrez, Source | Kruppel-like factor 10 | 8626 | -0.037 | -0.3125 | No |
| 63 | ACIN1 | ACIN1 Entrez, Source | apoptotic chromatin condensation inducer 1 | 8761 | -0.040 | -0.3206 | No |
| 64 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 8765 | -0.040 | -0.3187 | No |
| 65 | NUDT22 | NUDT22 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 22 | 8773 | -0.040 | -0.3172 | No |
| 66 | DNAJC7 | DNAJC7 Entrez, Source | DnaJ (Hsp40) homolog, subfamily C, member 7 | 9017 | -0.046 | -0.3331 | No |
| 67 | GRSF1 | GRSF1 Entrez, Source | G-rich RNA sequence binding factor 1 | 9138 | -0.050 | -0.3396 | No |
| 68 | CRK | CRK Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian) | 9176 | -0.051 | -0.3398 | No |
| 69 | ZFAND3 | ZFAND3 Entrez, Source | zinc finger, AN1-type domain 3 | 9406 | -0.057 | -0.3542 | No |
| 70 | EXOC5 | EXOC5 Entrez, Source | exocyst complex component 5 | 9426 | -0.058 | -0.3526 | No |
| 71 | CAPN7 | CAPN7 Entrez, Source | calpain 7 | 9447 | -0.058 | -0.3511 | No |
| 72 | ROBO1 | ROBO1 Entrez, Source | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 9979 | -0.074 | -0.3874 | No |
| 73 | NRG1 | NRG1 Entrez, Source | neuregulin 1 | 10017 | -0.075 | -0.3863 | No |
| 74 | BECN1 | BECN1 Entrez, Source | beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) | 10058 | -0.076 | -0.3854 | No |
| 75 | PCBP2 | PCBP2 Entrez, Source | poly(rC) binding protein 2 | 10175 | -0.081 | -0.3900 | No |
| 76 | TRIM3 | TRIM3 Entrez, Source | tripartite motif-containing 3 | 10182 | -0.081 | -0.3862 | No |
| 77 | HSPA8 | HSPA8 Entrez, Source | heat shock 70kDa protein 8 | 10327 | -0.086 | -0.3927 | No |
| 78 | STC1 | STC1 Entrez, Source | stanniocalcin 1 | 10550 | -0.093 | -0.4046 | No |
| 79 | ADAMTS1 | ADAMTS1 Entrez, Source | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 10664 | -0.097 | -0.4081 | No |
| 80 | FXYD3 | FXYD3 Entrez, Source | FXYD domain containing ion transport regulator 3 | 10861 | -0.105 | -0.4175 | No |
| 81 | GARNL1 | GARNL1 Entrez, Source | GTPase activating Rap/RanGAP domain-like 1 | 10929 | -0.108 | -0.4169 | No |
| 82 | FGF13 | FGF13 Entrez, Source | fibroblast growth factor 13 | 10992 | -0.111 | -0.4159 | No |
| 83 | RIPK5 | RIPK5 Entrez, Source | receptor interacting protein kinase 5 | 11183 | -0.120 | -0.4240 | Yes |
| 84 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 11190 | -0.121 | -0.4182 | Yes |
| 85 | PLEKHA3 | PLEKHA3 Entrez, Source | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 | 11197 | -0.121 | -0.4123 | Yes |
| 86 | RNH1 | RNH1 Entrez, Source | ribonuclease/angiogenin inhibitor 1 | 11349 | -0.129 | -0.4171 | Yes |
| 87 | SDCBP | SDCBP Entrez, Source | syndecan binding protein (syntenin) | 11357 | -0.129 | -0.4109 | Yes |
| 88 | TGFBR2 | TGFBR2 Entrez, Source | transforming growth factor, beta receptor II (70/80kDa) | 11501 | -0.137 | -0.4146 | Yes |
| 89 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 11529 | -0.139 | -0.4094 | Yes |
| 90 | SYNJ1 | SYNJ1 Entrez, Source | synaptojanin 1 | 11551 | -0.140 | -0.4037 | Yes |
| 91 | SON | SON Entrez, Source | SON DNA binding protein | 11552 | -0.140 | -0.3964 | Yes |
| 92 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 11599 | -0.144 | -0.3924 | Yes |
| 93 | BTG3 | BTG3 Entrez, Source | BTG family, member 3 | 11661 | -0.148 | -0.3894 | Yes |
| 94 | AP1G1 | AP1G1 Entrez, Source | adaptor-related protein complex 1, gamma 1 subunit | 11677 | -0.148 | -0.3828 | Yes |
| 95 | CBX3 | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 11802 | -0.156 | -0.3841 | Yes |
| 96 | FBXO30 | FBXO30 Entrez, Source | F-box protein 30 | 11851 | -0.160 | -0.3794 | Yes |
| 97 | SLC18A2 | SLC18A2 Entrez, Source | solute carrier family 18 (vesicular monoamine), member 2 | 12001 | -0.173 | -0.3817 | Yes |
| 98 | NFE2L2 | NFE2L2 Entrez, Source | nuclear factor (erythroid-derived 2)-like 2 | 12065 | -0.179 | -0.3771 | Yes |
| 99 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 12093 | -0.181 | -0.3698 | Yes |
| 100 | CDK5 | CDK5 Entrez, Source | cyclin-dependent kinase 5 | 12107 | -0.182 | -0.3613 | Yes |
| 101 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12269 | -0.201 | -0.3631 | Yes |
| 102 | SNX16 | SNX16 Entrez, Source | sorting nexin 16 | 12373 | -0.212 | -0.3599 | Yes |
| 103 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 12493 | -0.227 | -0.3571 | Yes |
| 104 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 12496 | -0.228 | -0.3454 | Yes |
| 105 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 12499 | -0.229 | -0.3336 | Yes |
| 106 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 12519 | -0.231 | -0.3231 | Yes |
| 107 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 12557 | -0.237 | -0.3136 | Yes |
| 108 | TRIP10 | TRIP10 Entrez, Source | thyroid hormone receptor interactor 10 | 12606 | -0.246 | -0.3044 | Yes |
| 109 | BTBD10 | BTBD10 Entrez, Source | BTB (POZ) domain containing 10 | 12646 | -0.253 | -0.2942 | Yes |
| 110 | QKI | QKI Entrez, Source | quaking homolog, KH domain RNA binding (mouse) | 12675 | -0.260 | -0.2829 | Yes |
| 111 | TCF12 | TCF12 Entrez, Source | transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) | 12690 | -0.262 | -0.2703 | Yes |
| 112 | ARID4B | ARID4B Entrez, Source | AT rich interactive domain 4B (RBP1- like) | 12758 | -0.277 | -0.2610 | Yes |
| 113 | JMJD1C | JMJD1C Entrez, Source | jumonji domain containing 1C | 12770 | -0.278 | -0.2474 | Yes |
| 114 | PCTK2 | PCTK2 Entrez, Source | PCTAIRE protein kinase 2 | 12886 | -0.316 | -0.2397 | Yes |
| 115 | ADAMTS5 | ADAMTS5 Entrez, Source | ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) | 12912 | -0.326 | -0.2247 | Yes |
| 116 | HN1 | HN1 Entrez, Source | hematological and neurological expressed 1 | 13064 | -0.406 | -0.2150 | Yes |
| 117 | MMP24 | MMP24 Entrez, Source | matrix metallopeptidase 24 (membrane-inserted) | 13076 | -0.411 | -0.1945 | Yes |
| 118 | RHOQ | RHOQ Entrez, Source | ras homolog gene family, member Q | 13078 | -0.412 | -0.1732 | Yes |
| 119 | RCN2 | RCN2 Entrez, Source | reticulocalbin 2, EF-hand calcium binding domain | 13084 | -0.414 | -0.1520 | Yes |
| 120 | CD69 | CD69 Entrez, Source | CD69 molecule | 13130 | -0.450 | -0.1321 | Yes |
| 121 | TPBG | TPBG Entrez, Source | trophoblast glycoprotein | 13155 | -0.487 | -0.1086 | Yes |
| 122 | RTN1 | RTN1 Entrez, Source | reticulon 1 | 13181 | -0.527 | -0.0831 | Yes |
| 123 | KITLG | KITLG Entrez, Source | KIT ligand | 13294 | -0.868 | -0.0465 | Yes |
| 124 | BHLHB3 | BHLHB3 Entrez, Source | basic helix-loop-helix domain containing, class B, 3 | 13305 | -0.964 | 0.0028 | Yes |
