Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ADIPOGENESIS_HMSC_CLASS3_UP |
| Enrichment Score (ES) | 0.55245817 |
| Normalized Enrichment Score (NES) | 1.7732297 |
| Nominal p-value | 0.0021141649 |
| FDR q-value | 0.017626144 |
| FWER p-Value | 0.946 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 6 | 1.218 | 0.1294 | Yes |
| 2 | LPIN1 | LPIN1 Entrez, Source | lipin 1 | 43 | 0.774 | 0.2093 | Yes |
| 3 | INSIG1 | INSIG1 Entrez, Source | insulin induced gene 1 | 83 | 0.642 | 0.2748 | Yes |
| 4 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 84 | 0.641 | 0.3431 | Yes |
| 5 | ACACA | ACACA Entrez, Source | acetyl-Coenzyme A carboxylase alpha | 154 | 0.527 | 0.3942 | Yes |
| 6 | HMGCS1 | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 199 | 0.477 | 0.4417 | Yes |
| 7 | FASN | FASN Entrez, Source | fatty acid synthase | 213 | 0.460 | 0.4897 | Yes |
| 8 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 867 | 0.212 | 0.4632 | Yes |
| 9 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 947 | 0.200 | 0.4786 | Yes |
| 10 | ADFP | ADFP Entrez, Source | adipose differentiation-related protein | 1069 | 0.185 | 0.4893 | Yes |
| 11 | NFE2 | NFE2 Entrez, Source | nuclear factor (erythroid-derived 2), 45kDa | 1071 | 0.185 | 0.5089 | Yes |
| 12 | NAB1 | NAB1 Entrez, Source | NGFI-A binding protein 1 (EGR1 binding protein 1) | 1245 | 0.167 | 0.5137 | Yes |
| 13 | LEPREL1 | LEPREL1 Entrez, Source | leprecan-like 1 | 1321 | 0.163 | 0.5255 | Yes |
| 14 | CDH13 | CDH13 Entrez, Source | cadherin 13, H-cadherin (heart) | 1338 | 0.162 | 0.5415 | Yes |
| 15 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 1414 | 0.156 | 0.5525 | Yes |
| 16 | ACACB | ACACB Entrez, Source | acetyl-Coenzyme A carboxylase beta | 2014 | 0.121 | 0.5203 | No |
| 17 | TMEM23 | TMEM23 Entrez, Source | transmembrane protein 23 | 2473 | 0.104 | 0.4969 | No |
| 18 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 2538 | 0.101 | 0.5030 | No |
| 19 | PHKG1 | PHKG1 Entrez, Source | phosphorylase kinase, gamma 1 (muscle) | 3219 | 0.078 | 0.4601 | No |
| 20 | LIPE | LIPE Entrez, Source | lipase, hormone-sensitive | 4076 | 0.058 | 0.4019 | No |
| 21 | ACSL5 | ACSL5 Entrez, Source | acyl-CoA synthetase long-chain family member 5 | 4466 | 0.049 | 0.3779 | No |
| 22 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 6465 | 0.008 | 0.2286 | No |
| 23 | NID1 | NID1 Entrez, Source | nidogen 1 | 6775 | 0.003 | 0.2056 | No |
| 24 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 7316 | -0.009 | 0.1659 | No |
| 25 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 7490 | -0.012 | 0.1542 | No |
| 26 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 8322 | -0.030 | 0.0950 | No |
| 27 | GAS6 | GAS6 Entrez, Source | growth arrest-specific 6 | 8485 | -0.034 | 0.0864 | No |
| 28 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 8785 | -0.040 | 0.0683 | No |
| 29 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 8967 | -0.045 | 0.0595 | No |
| 30 | STOM | STOM Entrez, Source | stomatin | 9313 | -0.055 | 0.0393 | No |
| 31 | MGP | MGP Entrez, Source | matrix Gla protein | 9643 | -0.064 | 0.0214 | No |
| 32 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 9749 | -0.067 | 0.0206 | No |
| 33 | CYBRD1 | CYBRD1 Entrez, Source | cytochrome b reductase 1 | 10038 | -0.076 | 0.0070 | No |
| 34 | ITGAM | ITGAM Entrez, Source | integrin, alpha M (complement component 3 receptor 3 subunit) | 10046 | -0.076 | 0.0146 | No |
| 35 | SLC27A4 | SLC27A4 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 4 | 10628 | -0.096 | -0.0188 | No |
| 36 | PPP2R1B | PPP2R1B Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform | 11027 | -0.113 | -0.0367 | No |
| 37 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 11315 | -0.127 | -0.0447 | No |
| 38 | NPTXR | NPTXR Entrez, Source | neuronal pentraxin receptor | 11612 | -0.144 | -0.0516 | No |
| 39 | GM2A | GM2A Entrez, Source | GM2 ganglioside activator | 11694 | -0.149 | -0.0418 | No |
| 40 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 11744 | -0.152 | -0.0293 | No |
| 41 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 12519 | -0.231 | -0.0629 | No |
| 42 | STX3 | STX3 Entrez, Source | syntaxin 3 | 12884 | -0.315 | -0.0566 | No |
| 43 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 13002 | -0.366 | -0.0264 | No |
| 44 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 13154 | -0.487 | 0.0141 | No |
