Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ADIP_VS_FIBRO_UP |
| Enrichment Score (ES) | 0.7196746 |
| Normalized Enrichment Score (NES) | 2.1225014 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.9629158E-4 |
| FWER p-Value | 0.018 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PC | PC Entrez, Source | pyruvate carboxylase | 79 | 0.652 | 0.1092 | Yes |
| 2 | FASN | FASN Entrez, Source | fatty acid synthase | 213 | 0.460 | 0.1805 | Yes |
| 3 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 236 | 0.445 | 0.2574 | Yes |
| 4 | CPT2 | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 292 | 0.402 | 0.3242 | Yes |
| 5 | GHR | GHR Entrez, Source | growth hormone receptor | 312 | 0.389 | 0.3914 | Yes |
| 6 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 335 | 0.375 | 0.4560 | Yes |
| 7 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 389 | 0.344 | 0.5127 | Yes |
| 8 | AGT | AGT Entrez, Source | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 514 | 0.295 | 0.5555 | Yes |
| 9 | ACADVL | ACADVL Entrez, Source | acyl-Coenzyme A dehydrogenase, very long chain | 537 | 0.288 | 0.6047 | Yes |
| 10 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 585 | 0.271 | 0.6490 | Yes |
| 11 | SCP2 | SCP2 Entrez, Source | sterol carrier protein 2 | 624 | 0.260 | 0.6920 | Yes |
| 12 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 947 | 0.200 | 0.7032 | Yes |
| 13 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 1296 | 0.164 | 0.7061 | Yes |
| 14 | VEGFB | VEGFB Entrez, Source | vascular endothelial growth factor B | 1471 | 0.151 | 0.7197 | Yes |
| 15 | COX8A | COX8A Entrez, Source | cytochrome c oxidase subunit 8A (ubiquitous) | 2501 | 0.102 | 0.6605 | No |
| 16 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 2538 | 0.101 | 0.6757 | No |
| 17 | STAT3 | STAT3 Entrez, Source | signal transducer and activator of transcription 3 (acute-phase response factor) | 2914 | 0.088 | 0.6630 | No |
| 18 | LIPE | LIPE Entrez, Source | lipase, hormone-sensitive | 4076 | 0.058 | 0.5860 | No |
| 19 | ITGA7 | ITGA7 Entrez, Source | integrin, alpha 7 | 4309 | 0.053 | 0.5778 | No |
| 20 | PDHA1 | PDHA1 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 1 | 4772 | 0.042 | 0.5506 | No |
| 21 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 4814 | 0.042 | 0.5549 | No |
| 22 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 4819 | 0.041 | 0.5619 | No |
| 23 | SPARCL1 | SPARCL1 Entrez, Source | SPARC-like 1 (mast9, hevin) | 5171 | 0.035 | 0.5416 | No |
| 24 | CRAT | CRAT Entrez, Source | carnitine acetyltransferase | 5716 | 0.023 | 0.5049 | No |
| 25 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 6279 | 0.012 | 0.4648 | No |
| 26 | ADIPOQ | ADIPOQ Entrez, Source | adiponectin, C1Q and collagen domain containing | 6570 | 0.007 | 0.4442 | No |
| 27 | GPX4 | GPX4 Entrez, Source | glutathione peroxidase 4 (phospholipid hydroperoxidase) | 6721 | 0.004 | 0.4336 | No |
| 28 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 8765 | -0.040 | 0.2872 | No |
| 29 | GCLM | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 8939 | -0.045 | 0.2820 | No |
| 30 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 10723 | -0.099 | 0.1656 | No |
| 31 | VLDLR | VLDLR Entrez, Source | very low density lipoprotein receptor | 12034 | -0.176 | 0.0983 | No |
