Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | AMINO_ACID_CATABOLIC_PROCESS |
| Enrichment Score (ES) | 0.6413655 |
| Normalized Enrichment Score (NES) | 1.7604575 |
| Nominal p-value | 0.006329114 |
| FDR q-value | 0.01969461 |
| FWER p-Value | 0.967 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 17 | 0.930 | 0.1537 | Yes |
| 2 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 56 | 0.731 | 0.2726 | Yes |
| 3 | ASL | ASL Entrez, Source | argininosuccinate lyase | 122 | 0.586 | 0.3654 | Yes |
| 4 | ARG1 | ARG1 Entrez, Source | arginase, liver | 246 | 0.438 | 0.4291 | Yes |
| 5 | BCKDHB | BCKDHB Entrez, Source | branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) | 271 | 0.419 | 0.4972 | Yes |
| 6 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 277 | 0.416 | 0.5662 | Yes |
| 7 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 389 | 0.344 | 0.6153 | Yes |
| 8 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 1027 | 0.189 | 0.5990 | Yes |
| 9 | GCSH | GCSH Entrez, Source | glycine cleavage system protein H (aminomethyl carrier) | 1046 | 0.187 | 0.6289 | Yes |
| 10 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 1252 | 0.167 | 0.6414 | Yes |
| 11 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 1864 | 0.128 | 0.6168 | No |
| 12 | ASRGL1 | ASRGL1 Entrez, Source | asparaginase like 1 | 2968 | 0.086 | 0.5483 | No |
| 13 | BCKDK | BCKDK Entrez, Source | branched chain ketoacid dehydrogenase kinase | 3082 | 0.082 | 0.5535 | No |
| 14 | AMT | AMT Entrez, Source | aminomethyltransferase | 3875 | 0.063 | 0.5045 | No |
| 15 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 5183 | 0.034 | 0.4121 | No |
| 16 | MCCC2 | MCCC2 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 2 (beta) | 6381 | 0.010 | 0.3239 | No |
| 17 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 7234 | -0.007 | 0.2612 | No |
| 18 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 8124 | -0.026 | 0.1988 | No |
| 19 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 9551 | -0.061 | 0.1019 | No |
| 20 | DDAH1 | DDAH1 Entrez, Source | dimethylarginine dimethylaminohydrolase 1 | 12983 | -0.354 | -0.0966 | No |
| 21 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 13266 | -0.741 | 0.0057 | No |
