Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ANDROGEN_GENES |
| Enrichment Score (ES) | 0.5680208 |
| Normalized Enrichment Score (NES) | 1.6580461 |
| Nominal p-value | 0.0080 |
| FDR q-value | 0.046503488 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NR1I3 | NR1I3 Entrez, Source | nuclear receptor subfamily 1, group I, member 3 | 47 | 0.769 | 0.1565 | Yes |
| 2 | HSD17B2 | HSD17B2 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 2 | 280 | 0.415 | 0.2253 | Yes |
| 3 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 293 | 0.402 | 0.3080 | Yes |
| 4 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 343 | 0.371 | 0.3814 | Yes |
| 5 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 405 | 0.337 | 0.4470 | Yes |
| 6 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 487 | 0.306 | 0.5045 | Yes |
| 7 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 656 | 0.251 | 0.5441 | Yes |
| 8 | AR | AR Entrez, Source | androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) | 1135 | 0.178 | 0.5451 | Yes |
| 9 | STS | STS Entrez, Source | steroid sulfatase (microsomal), arylsulfatase C, isozyme S | 1743 | 0.134 | 0.5275 | Yes |
| 10 | RDH11 | RDH11 Entrez, Source | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 2018 | 0.121 | 0.5321 | Yes |
| 11 | ARSE | ARSE Entrez, Source | arylsulfatase E (chondrodysplasia punctata 1) | 2110 | 0.117 | 0.5496 | Yes |
| 12 | HSD17B3 | HSD17B3 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 3 | 2606 | 0.099 | 0.5330 | Yes |
| 13 | SULT2A1 | SULT2A1 Entrez, Source | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 2731 | 0.094 | 0.5434 | Yes |
| 14 | RNF14 | RNF14 Entrez, Source | ring finger protein 14 | 2739 | 0.094 | 0.5624 | Yes |
| 15 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2909 | 0.088 | 0.5680 | Yes |
| 16 | HSD17B8 | HSD17B8 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 8 | 3280 | 0.077 | 0.5561 | No |
| 17 | RWDD1 | RWDD1 Entrez, Source | RWD domain containing 1 | 3474 | 0.072 | 0.5566 | No |
| 18 | TMPRSS2 | TMPRSS2 Entrez, Source | transmembrane protease, serine 2 | 3889 | 0.062 | 0.5384 | No |
| 19 | AKR1B10 | AKR1B10 Entrez, Source | aldo-keto reductase family 1, member B10 (aldose reductase) | 4097 | 0.057 | 0.5348 | No |
| 20 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4791 | 0.042 | 0.4915 | No |
| 21 | PPAP2A | PPAP2A Entrez, Source | phosphatidic acid phosphatase type 2A | 5751 | 0.023 | 0.4242 | No |
| 22 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 6111 | 0.016 | 0.4006 | No |
| 23 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 6493 | 0.008 | 0.3736 | No |
| 24 | CYP11B1 | CYP11B1 Entrez, Source | cytochrome P450, family 11, subfamily B, polypeptide 1 | 7700 | -0.017 | 0.2864 | No |
| 25 | FGF8 | FGF8 Entrez, Source | fibroblast growth factor 8 (androgen-induced) | 8216 | -0.028 | 0.2536 | No |
| 26 | SHBG | SHBG Entrez, Source | sex hormone-binding globulin | 9271 | -0.054 | 0.1855 | No |
| 27 | RAN | RAN Entrez, Source | RAN, member RAS oncogene family | 9534 | -0.061 | 0.1785 | No |
| 28 | CRISP1 | CRISP1 Entrez, Source | cysteine-rich secretory protein 1 | 10195 | -0.081 | 0.1458 | No |
| 29 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 10284 | -0.084 | 0.1567 | No |
| 30 | CRSP6 | CRSP6 Entrez, Source | cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa | 11103 | -0.117 | 0.1196 | No |
| 31 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 12535 | -0.233 | 0.0606 | No |
