Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | AROMATIC_COMPOUND_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.7283956 |
| Normalized Enrichment Score (NES) | 1.9581462 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0028792417 |
| FWER p-Value | 0.237 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FTCD | FTCD Entrez, Source | formiminotransferase cyclodeaminase | 9 | 1.171 | 0.2396 | Yes |
| 2 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 17 | 0.930 | 0.4298 | Yes |
| 3 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 277 | 0.416 | 0.4957 | Yes |
| 4 | MOCS2 | MOCS2 Entrez, Source | molybdenum cofactor synthesis 2 | 352 | 0.361 | 0.5643 | Yes |
| 5 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 524 | 0.292 | 0.6114 | Yes |
| 6 | SULT1B1 | SULT1B1 Entrez, Source | sulfotransferase family, cytosolic, 1B, member 1 | 743 | 0.229 | 0.6421 | Yes |
| 7 | ALDH1L1 | ALDH1L1 Entrez, Source | aldehyde dehydrogenase 1 family, member L1 | 750 | 0.228 | 0.6883 | Yes |
| 8 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 870 | 0.211 | 0.7227 | Yes |
| 9 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 1252 | 0.167 | 0.7284 | Yes |
| 10 | PTS | PTS Entrez, Source | 6-pyruvoyltetrahydropterin synthase | 1785 | 0.132 | 0.7156 | No |
| 11 | SPR | SPR Entrez, Source | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 2551 | 0.101 | 0.6789 | No |
| 12 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 4665 | 0.045 | 0.5295 | No |
| 13 | HPRT1 | HPRT1 Entrez, Source | hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) | 7238 | -0.007 | 0.3380 | No |
| 14 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 8124 | -0.026 | 0.2769 | No |
| 15 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 10317 | -0.085 | 0.1299 | No |
| 16 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 10338 | -0.086 | 0.1460 | No |
| 17 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 10477 | -0.091 | 0.1543 | No |
| 18 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12832 | -0.296 | 0.0383 | No |
