Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | ATRIA_UP |
| Enrichment Score (ES) | -0.43288526 |
| Normalized Enrichment Score (NES) | -1.6435454 |
| Nominal p-value | 0.0018181818 |
| FDR q-value | 0.10026877 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 294 | 0.400 | -0.0028 | No |
| 2 | AGTR1 | AGTR1 Entrez, Source | angiotensin II receptor, type 1 | 341 | 0.372 | 0.0117 | No |
| 3 | PDE4B | PDE4B Entrez, Source | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) | 367 | 0.356 | 0.0271 | No |
| 4 | FGFR2 | FGFR2 Entrez, Source | ffer syndrome, Jackson-Weiss syndrome) | 406 | 0.337 | 0.0406 | No |
| 5 | SLC39A8 | SLC39A8 Entrez, Source | solute carrier family 39 (zinc transporter), member 8 | 526 | 0.292 | 0.0458 | No |
| 6 | SLC11A2 | SLC11A2 Entrez, Source | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 538 | 0.287 | 0.0589 | No |
| 7 | KCNK1 | KCNK1 Entrez, Source | potassium channel, subfamily K, member 1 | 874 | 0.211 | 0.0438 | No |
| 8 | SLC22A18 | SLC22A18 Entrez, Source | solute carrier family 22 (organic cation transporter), member 18 | 901 | 0.207 | 0.0518 | No |
| 9 | DAPK2 | DAPK2 Entrez, Source | death-associated protein kinase 2 | 973 | 0.198 | 0.0561 | No |
| 10 | RARRES2 | RARRES2 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 2 | 1079 | 0.184 | 0.0570 | No |
| 11 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 1094 | 0.183 | 0.0649 | No |
| 12 | DGKZ | DGKZ Entrez, Source | diacylglycerol kinase, zeta 104kDa | 1297 | 0.164 | 0.0575 | No |
| 13 | ADORA1 | ADORA1 Entrez, Source | adenosine A1 receptor | 1508 | 0.149 | 0.0489 | No |
| 14 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | 0.0540 | No |
| 15 | INPP1 | INPP1 Entrez, Source | inositol polyphosphate-1-phosphatase | 1564 | 0.145 | 0.0589 | No |
| 16 | FEZ1 | FEZ1 Entrez, Source | fasciculation and elongation protein zeta 1 (zygin I) | 1580 | 0.144 | 0.0648 | No |
| 17 | PLA2G2A | PLA2G2A Entrez, Source | phospholipase A2, group IIA (platelets, synovial fluid) | 1721 | 0.136 | 0.0608 | No |
| 18 | STAT4 | STAT4 Entrez, Source | signal transducer and activator of transcription 4 | 1945 | 0.124 | 0.0499 | No |
| 19 | CHRNE | CHRNE Entrez, Source | cholinergic receptor, nicotinic, epsilon | 1954 | 0.124 | 0.0554 | No |
| 20 | MIPEP | MIPEP Entrez, Source | mitochondrial intermediate peptidase | 1964 | 0.123 | 0.0606 | No |
| 21 | FGL2 | FGL2 Entrez, Source | fibrinogen-like 2 | 2103 | 0.118 | 0.0559 | No |
| 22 | SFRP1 | SFRP1 Entrez, Source | secreted frizzled-related protein 1 | 2213 | 0.114 | 0.0532 | No |
| 23 | IGFBP6 | IGFBP6 Entrez, Source | insulin-like growth factor binding protein 6 | 2548 | 0.101 | 0.0328 | No |
| 24 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 2590 | 0.100 | 0.0345 | No |
| 25 | DHODH | DHODH Entrez, Source | dihydroorotate dehydrogenase | 2752 | 0.094 | 0.0269 | No |
| 26 | PLA2G5 | PLA2G5 Entrez, Source | phospholipase A2, group V | 2925 | 0.087 | 0.0181 | No |
| 27 | CACNA1B | CACNA1B Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1B subunit | 2946 | 0.087 | 0.0208 | No |
| 28 | CHGB | CHGB Entrez, Source | chromogranin B (secretogranin 1) | 3046 | 0.084 | 0.0174 | No |
| 29 | KDELR2 | KDELR2 Entrez, Source | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 3147 | 0.080 | 0.0137 | No |
| 30 | TOR1A | TOR1A Entrez, Source | torsin family 1, member A (torsin A) | 3215 | 0.078 | 0.0124 | No |
| 31 | TMEM106C | TMEM106C Entrez, Source | transmembrane protein 106C | 3318 | 0.076 | 0.0084 | No |
| 32 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 3366 | 0.074 | 0.0084 | No |
| 33 | NRTN | NRTN Entrez, Source | neurturin | 3501 | 0.071 | 0.0017 | No |
| 34 | WISP2 | WISP2 Entrez, Source | WNT1 inducible signaling pathway protein 2 | 3896 | 0.062 | -0.0251 | No |
| 35 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 4354 | 0.052 | -0.0572 | No |
| 36 | CREB3L2 | CREB3L2 Entrez, Source | cAMP responsive element binding protein 3-like 2 | 4457 | 0.049 | -0.0625 | No |
| 37 | PPIB | PPIB Entrez, Source | peptidylprolyl isomerase B (cyclophilin B) | 4525 | 0.048 | -0.0652 | No |
| 38 | VSNL1 | VSNL1 Entrez, Source | visinin-like 1 | 4526 | 0.048 | -0.0629 | No |
| 39 | FEV | FEV Entrez, Source | FEV (ETS oncogene family) | 4641 | 0.045 | -0.0693 | No |
| 40 | RBP1 | RBP1 Entrez, Source | retinol binding protein 1, cellular | 4881 | 0.040 | -0.0855 | No |
| 41 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 4900 | 0.040 | -0.0849 | No |
| 42 | SLN | SLN Entrez, Source | sarcolipin | 4980 | 0.038 | -0.0890 | No |
| 43 | TBX5 | TBX5 Entrez, Source | T-box 5 | 5116 | 0.036 | -0.0975 | No |
| 44 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 5315 | 0.032 | -0.1110 | No |
| 45 | COMP | COMP Entrez, Source | cartilage oligomeric matrix protein | 5328 | 0.031 | -0.1104 | No |
| 46 | C10ORF7 | C10ORF7 Entrez, Source | chromosome 10 open reading frame 7 | 5602 | 0.025 | -0.1298 | No |
| 47 | GNB5 | GNB5 Entrez, Source | guanine nucleotide binding protein (G protein), beta 5 | 5739 | 0.023 | -0.1390 | No |
| 48 | KCNA5 | KCNA5 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 5 | 5774 | 0.022 | -0.1405 | No |
| 49 | PIP5K2B | PIP5K2B Entrez, Source | phosphatidylinositol-4-phosphate 5-kinase, type II, beta | 5868 | 0.021 | -0.1465 | No |
| 50 | CDC2L5 | CDC2L5 Entrez, Source | cell division cycle 2-like 5 (cholinesterase-related cell division controller) | 5925 | 0.020 | -0.1498 | No |
| 51 | SLIT3 | SLIT3 Entrez, Source | slit homolog 3 (Drosophila) | 5940 | 0.020 | -0.1499 | No |
| 52 | FMOD | FMOD Entrez, Source | fibromodulin | 6548 | 0.007 | -0.1955 | No |
| 53 | CALR | CALR Entrez, Source | calreticulin | 6558 | 0.007 | -0.1958 | No |
| 54 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 6602 | 0.006 | -0.1988 | No |
| 55 | PDE8B | PDE8B Entrez, Source | phosphodiesterase 8B | 6680 | 0.005 | -0.2044 | No |
| 56 | NAP1L1 | NAP1L1 Entrez, Source | nucleosome assembly protein 1-like 1 | 6915 | -0.000 | -0.2221 | No |
| 57 | MYBPC1 | MYBPC1 Entrez, Source | myosin binding protein C, slow type | 7017 | -0.002 | -0.2296 | No |
| 58 | PLCB1 | PLCB1 Entrez, Source | phospholipase C, beta 1 (phosphoinositide-specific) | 7055 | -0.003 | -0.2323 | No |
| 59 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 7183 | -0.006 | -0.2416 | No |
| 60 | AFAP | AFAP Entrez, Source | - | 7458 | -0.011 | -0.2618 | No |
| 61 | PTHR1 | PTHR1 Entrez, Source | parathyroid hormone receptor 1 | 7539 | -0.013 | -0.2672 | No |
| 62 | EEF1A1 | EEF1A1 Entrez, Source | eukaryotic translation elongation factor 1 alpha 1 | 7913 | -0.021 | -0.2944 | No |
| 63 | TMED3 | TMED3 Entrez, Source | transmembrane emp24 protein transport domain containing 3 | 8092 | -0.025 | -0.3067 | No |
| 64 | IL1RL1 | IL1RL1 Entrez, Source | interleukin 1 receptor-like 1 | 8104 | -0.026 | -0.3063 | No |
| 65 | SYNPO | SYNPO Entrez, Source | synaptopodin | 8210 | -0.028 | -0.3129 | No |
| 66 | MAGED1 | MAGED1 Entrez, Source | melanoma antigen family D, 1 | 8492 | -0.034 | -0.3325 | No |
| 67 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 8690 | -0.039 | -0.3455 | No |
| 68 | ZFP36L2 | ZFP36L2 Entrez, Source | zinc finger protein 36, C3H type-like 2 | 8772 | -0.040 | -0.3497 | No |
| 69 | HYOU1 | HYOU1 Entrez, Source | hypoxia up-regulated 1 | 8888 | -0.043 | -0.3563 | No |
| 70 | CELSR2 | CELSR2 Entrez, Source | cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) | 8972 | -0.045 | -0.3604 | No |
| 71 | NTRK2 | NTRK2 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 2 | 9007 | -0.046 | -0.3607 | No |
| 72 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 9340 | -0.055 | -0.3832 | No |
| 73 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 9375 | -0.057 | -0.3830 | No |
| 74 | GRIN2C | GRIN2C Entrez, Source | glutamate receptor, ionotropic, N-methyl D-aspartate 2C | 9415 | -0.057 | -0.3832 | No |
| 75 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 9756 | -0.067 | -0.4057 | No |
| 76 | PDE2A | PDE2A Entrez, Source | phosphodiesterase 2A, cGMP-stimulated | 9810 | -0.069 | -0.4063 | No |
| 77 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 9992 | -0.074 | -0.4164 | No |
| 78 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 10001 | -0.075 | -0.4134 | No |
| 79 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 10123 | -0.079 | -0.4187 | No |
| 80 | ITSN1 | ITSN1 Entrez, Source | intersectin 1 (SH3 domain protein) | 10184 | -0.081 | -0.4194 | No |
| 81 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 10276 | -0.084 | -0.4222 | No |
| 82 | SLC9A1 | SLC9A1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) | 10314 | -0.085 | -0.4208 | No |
| 83 | RABAC1 | RABAC1 Entrez, Source | Rab acceptor 1 (prenylated) | 10331 | -0.086 | -0.4179 | No |
| 84 | FBLN2 | FBLN2 Entrez, Source | fibulin 2 | 10393 | -0.088 | -0.4182 | No |
| 85 | QSCN6 | QSCN6 Entrez, Source | quiescin Q6 | 10576 | -0.094 | -0.4274 | No |
| 86 | AGPAT1 | AGPAT1 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) | 10638 | -0.097 | -0.4274 | No |
| 87 | PRDX1 | PRDX1 Entrez, Source | peroxiredoxin 1 | 10681 | -0.098 | -0.4258 | No |
| 88 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 10743 | -0.100 | -0.4255 | No |
| 89 | CADPS | CADPS Entrez, Source | Ca2+-dependent secretion activator | 10841 | -0.105 | -0.4278 | Yes |
| 90 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 10850 | -0.105 | -0.4233 | Yes |
| 91 | CD81 | CD81 Entrez, Source | CD81 molecule | 10933 | -0.108 | -0.4243 | Yes |
| 92 | PLOD3 | PLOD3 Entrez, Source | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 10940 | -0.109 | -0.4195 | Yes |
| 93 | TNK2 | TNK2 Entrez, Source | tyrosine kinase, non-receptor, 2 | 11023 | -0.113 | -0.4202 | Yes |
| 94 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 11133 | -0.119 | -0.4227 | Yes |
| 95 | DAP | DAP Entrez, Source | death-associated protein | 11144 | -0.119 | -0.4177 | Yes |
| 96 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 11212 | -0.122 | -0.4168 | Yes |
| 97 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 11278 | -0.125 | -0.4156 | Yes |
| 98 | USP11 | USP11 Entrez, Source | ubiquitin specific peptidase 11 | 11285 | -0.126 | -0.4100 | Yes |
| 99 | CIB2 | CIB2 Entrez, Source | calcium and integrin binding family member 2 | 11337 | -0.128 | -0.4076 | Yes |
| 100 | PLXNB2 | PLXNB2 Entrez, Source | plexin B2 | 11356 | -0.129 | -0.4027 | Yes |
| 101 | SGCE | SGCE Entrez, Source | sarcoglycan, epsilon | 11390 | -0.131 | -0.3989 | Yes |
| 102 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 11420 | -0.132 | -0.3947 | Yes |
| 103 | CD47 | CD47 Entrez, Source | CD47 molecule | 11473 | -0.136 | -0.3920 | Yes |
| 104 | SMARCD2 | SMARCD2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 11555 | -0.140 | -0.3913 | Yes |
| 105 | BTG3 | BTG3 Entrez, Source | BTG family, member 3 | 11661 | -0.148 | -0.3921 | Yes |
| 106 | BAD | BAD Entrez, Source | BCL2-antagonist of cell death | 11752 | -0.152 | -0.3915 | Yes |
| 107 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 11984 | -0.171 | -0.4007 | Yes |
| 108 | CTSF | CTSF Entrez, Source | cathepsin F | 11996 | -0.172 | -0.3931 | Yes |
| 109 | FRMD4B | FRMD4B Entrez, Source | FERM domain containing 4B | 12201 | -0.192 | -0.3993 | Yes |
| 110 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12216 | -0.193 | -0.3909 | Yes |
| 111 | ERBB2 | ERBB2 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 12237 | -0.197 | -0.3829 | Yes |
| 112 | VAMP5 | VAMP5 Entrez, Source | vesicle-associated membrane protein 5 (myobrevin) | 12345 | -0.209 | -0.3808 | Yes |
| 113 | RELN | RELN Entrez, Source | reelin | 12369 | -0.211 | -0.3723 | Yes |
| 114 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 12405 | -0.215 | -0.3645 | Yes |
| 115 | SOD3 | SOD3 Entrez, Source | superoxide dismutase 3, extracellular | 12512 | -0.230 | -0.3613 | Yes |
| 116 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 12531 | -0.233 | -0.3514 | Yes |
| 117 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 12535 | -0.233 | -0.3403 | Yes |
| 118 | BASP1 | BASP1 Entrez, Source | brain abundant, membrane attached signal protein 1 | 12594 | -0.244 | -0.3328 | Yes |
| 119 | PBXIP1 | PBXIP1 Entrez, Source | pre-B-cell leukemia transcription factor interacting protein 1 | 12721 | -0.269 | -0.3293 | Yes |
| 120 | ADM | ADM Entrez, Source | adrenomedullin | 12796 | -0.285 | -0.3211 | Yes |
| 121 | BAMBI | BAMBI Entrez, Source | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) | 12826 | -0.295 | -0.3090 | Yes |
| 122 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 12840 | -0.300 | -0.2954 | Yes |
| 123 | VAT1 | VAT1 Entrez, Source | vesicle amine transport protein 1 homolog (T californica) | 12903 | -0.323 | -0.2844 | Yes |
| 124 | GRN | GRN Entrez, Source | granulin | 12920 | -0.329 | -0.2697 | Yes |
| 125 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 13047 | -0.395 | -0.2600 | Yes |
| 126 | CRMP1 | CRMP1 Entrez, Source | collapsin response mediator protein 1 | 13115 | -0.440 | -0.2437 | Yes |
| 127 | GPX3 | GPX3 Entrez, Source | glutathione peroxidase 3 (plasma) | 13136 | -0.457 | -0.2231 | Yes |
| 128 | RTN4 | RTN4 Entrez, Source | reticulon 4 | 13160 | -0.500 | -0.2006 | Yes |
| 129 | PAM | PAM Entrez, Source | peptidylglycine alpha-amidating monooxygenase | 13208 | -0.576 | -0.1762 | Yes |
| 130 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13226 | -0.619 | -0.1474 | Yes |
| 131 | DPYSL3 | DPYSL3 Entrez, Source | dihydropyrimidinase-like 3 | 13228 | -0.625 | -0.1171 | Yes |
| 132 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13282 | -0.795 | -0.0825 | Yes |
| 133 | CPE | CPE Entrez, Source | carboxypeptidase E | 13342 | -1.792 | 0.0000 | Yes |
