Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | BAF57_BT549_UP |
| Enrichment Score (ES) | -0.49346077 |
| Normalized Enrichment Score (NES) | -1.8440273 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.034806203 |
| FWER p-Value | 0.747 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAP3K8 | MAP3K8 Entrez, Source | mitogen-activated protein kinase kinase kinase 8 | 34 | 0.817 | 0.0261 | No |
| 2 | GJB2 | GJB2 Entrez, Source | gap junction protein, beta 2, 26kDa (connexin 26) | 37 | 0.807 | 0.0542 | No |
| 3 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 168 | 0.502 | 0.0619 | No |
| 4 | GHR | GHR Entrez, Source | growth hormone receptor | 312 | 0.389 | 0.0647 | No |
| 5 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 325 | 0.381 | 0.0772 | No |
| 6 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 355 | 0.360 | 0.0876 | No |
| 7 | IGFBP4 | IGFBP4 Entrez, Source | insulin-like growth factor binding protein 4 | 456 | 0.317 | 0.0911 | No |
| 8 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 524 | 0.292 | 0.0963 | No |
| 9 | MAFB | MAFB Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) | 562 | 0.280 | 0.1033 | No |
| 10 | UNC5B | UNC5B Entrez, Source | unc-5 homolog B (C. elegans) | 591 | 0.270 | 0.1106 | No |
| 11 | FOXO1A | FOXO1A Entrez, Source | forkhead box O1A (rhabdomyosarcoma) | 596 | 0.268 | 0.1197 | No |
| 12 | IFIT2 | IFIT2 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 2 | 609 | 0.264 | 0.1281 | No |
| 13 | BTD | BTD Entrez, Source | biotinidase | 768 | 0.225 | 0.1240 | No |
| 14 | CFI | CFI Entrez, Source | complement factor I | 787 | 0.221 | 0.1304 | No |
| 15 | IGSF4 | IGSF4 Entrez, Source | immunoglobulin superfamily, member 4 | 821 | 0.218 | 0.1355 | No |
| 16 | EPAS1 | EPAS1 Entrez, Source | endothelial PAS domain protein 1 | 871 | 0.211 | 0.1392 | No |
| 17 | SDC2 | SDC2 Entrez, Source | syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) | 960 | 0.199 | 0.1395 | No |
| 18 | LIFR | LIFR Entrez, Source | leukemia inhibitory factor receptor alpha | 966 | 0.198 | 0.1461 | No |
| 19 | AGC1 | AGC1 Entrez, Source | aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) | 1197 | 0.171 | 0.1347 | No |
| 20 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 1217 | 0.169 | 0.1391 | No |
| 21 | SULF1 | SULF1 Entrez, Source | sulfatase 1 | 1230 | 0.168 | 0.1441 | No |
| 22 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 1407 | 0.156 | 0.1363 | No |
| 23 | IL13RA1 | IL13RA1 Entrez, Source | interleukin 13 receptor, alpha 1 | 1446 | 0.153 | 0.1388 | No |
| 24 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | 0.1373 | No |
| 25 | SERPINB3 | SERPINB3 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 2023 | 0.121 | 0.1046 | No |
| 26 | PAK3 | PAK3 Entrez, Source | p21 (CDKN1A)-activated kinase 3 | 2077 | 0.118 | 0.1048 | No |
| 27 | PROS1 | PROS1 Entrez, Source | protein S (alpha) | 2217 | 0.114 | 0.0982 | No |
| 28 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2222 | 0.114 | 0.1019 | No |
| 29 | SOCS3 | SOCS3 Entrez, Source | suppressor of cytokine signaling 3 | 2309 | 0.110 | 0.0992 | No |
| 30 | CTHRC1 | CTHRC1 Entrez, Source | collagen triple helix repeat containing 1 | 2319 | 0.109 | 0.1024 | No |
| 31 | CA4 | CA4 Entrez, Source | carbonic anhydrase IV | 2445 | 0.105 | 0.0966 | No |
| 32 | IGFBP6 | IGFBP6 Entrez, Source | insulin-like growth factor binding protein 6 | 2548 | 0.101 | 0.0924 | No |
| 33 | SLC44A1 | SLC44A1 Entrez, Source | solute carrier family 44, member 1 | 2779 | 0.092 | 0.0783 | No |
| 34 | SIPA1L1 | SIPA1L1 Entrez, Source | signal-induced proliferation-associated 1 like 1 | 2878 | 0.089 | 0.0739 | No |
| 35 | IRS1 | IRS1 Entrez, Source | insulin receptor substrate 1 | 3319 | 0.076 | 0.0433 | No |
| 36 | FNDC1 | FNDC1 Entrez, Source | fibronectin type III domain containing 1 | 3364 | 0.074 | 0.0426 | No |
| 37 | DLL1 | DLL1 Entrez, Source | delta-like 1 (Drosophila) | 3523 | 0.070 | 0.0331 | No |
| 38 | STRBP | STRBP Entrez, Source | spermatid perinuclear RNA binding protein | 3585 | 0.069 | 0.0309 | No |
| 39 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 3998 | 0.059 | 0.0018 | No |
| 40 | PLAG1 | PLAG1 Entrez, Source | pleiomorphic adenoma gene 1 | 4254 | 0.054 | -0.0157 | No |
| 41 | OXTR | OXTR Entrez, Source | oxytocin receptor | 4486 | 0.049 | -0.0314 | No |
| 42 | GAS5 | GAS5 Entrez, Source | growth arrest-specific 5 | 4547 | 0.047 | -0.0343 | No |
| 43 | KLRC2 | KLRC2 Entrez, Source | killer cell lectin-like receptor subfamily C, member 2 | 4834 | 0.041 | -0.0545 | No |
| 44 | CHI3L1 | CHI3L1 Entrez, Source | chitinase 3-like 1 (cartilage glycoprotein-39) | 4937 | 0.039 | -0.0609 | No |
| 45 | PARVA | PARVA Entrez, Source | parvin, alpha | 4999 | 0.038 | -0.0642 | No |
| 46 | ADD2 | ADD2 Entrez, Source | adducin 2 (beta) | 5257 | 0.033 | -0.0825 | No |
| 47 | ATXN1 | ATXN1 Entrez, Source | ataxin 1 | 5443 | 0.029 | -0.0955 | No |
| 48 | WT1 | WT1 Entrez, Source | Wilms tumor 1 | 5444 | 0.029 | -0.0944 | No |
| 49 | AVIL | AVIL Entrez, Source | advillin | 5517 | 0.027 | -0.0989 | No |
| 50 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 5666 | 0.024 | -0.1093 | No |
| 51 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 6093 | 0.016 | -0.1410 | No |
| 52 | SLC12A8 | SLC12A8 Entrez, Source | solute carrier family 12 (potassium/chloride transporters), member 8 | 6267 | 0.013 | -0.1536 | No |
| 53 | ANTXR1 | ANTXR1 Entrez, Source | anthrax toxin receptor 1 | 6416 | 0.009 | -0.1645 | No |
| 54 | NID1 | NID1 Entrez, Source | nidogen 1 | 6775 | 0.003 | -0.1915 | No |
| 55 | CD200 | CD200 Entrez, Source | CD200 molecule | 6909 | 0.000 | -0.2016 | No |
| 56 | DIO2 | DIO2 Entrez, Source | deiodinase, iodothyronine, type II | 6980 | -0.002 | -0.2068 | No |
| 57 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 7019 | -0.003 | -0.2096 | No |
| 58 | FZD1 | FZD1 Entrez, Source | frizzled homolog 1 (Drosophila) | 7166 | -0.006 | -0.2204 | No |
| 59 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 7328 | -0.009 | -0.2323 | No |
| 60 | SERPINB7 | SERPINB7 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | 7345 | -0.009 | -0.2332 | No |
| 61 | PRRX1 | PRRX1 Entrez, Source | paired related homeobox 1 | 7433 | -0.011 | -0.2394 | No |
| 62 | RPL37 | RPL37 Entrez, Source | ribosomal protein L37 | 7466 | -0.012 | -0.2414 | No |
| 63 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 7521 | -0.013 | -0.2451 | No |
| 64 | TES | TES Entrez, Source | testis derived transcript (3 LIM domains) | 7914 | -0.021 | -0.2740 | No |
| 65 | DCN | DCN Entrez, Source | decorin | 8220 | -0.028 | -0.2961 | No |
| 66 | PRSS35 | PRSS35 Entrez, Source | protease, serine, 35 | 8378 | -0.032 | -0.3069 | No |
| 67 | COL15A1 | COL15A1 Entrez, Source | collagen, type XV, alpha 1 | 8592 | -0.037 | -0.3217 | No |
| 68 | LUM | LUM Entrez, Source | lumican | 8618 | -0.037 | -0.3223 | No |
| 69 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 8649 | -0.038 | -0.3232 | No |
| 70 | GABBR2 | GABBR2 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 2 | 8703 | -0.039 | -0.3259 | No |
| 71 | FBXO32 | FBXO32 Entrez, Source | F-box protein 32 | 8720 | -0.039 | -0.3257 | No |
| 72 | RHOJ | RHOJ Entrez, Source | ras homolog gene family, member J | 8997 | -0.046 | -0.3450 | No |
| 73 | NTRK2 | NTRK2 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 2 | 9007 | -0.046 | -0.3441 | No |
| 74 | PMP22 | PMP22 Entrez, Source | peripheral myelin protein 22 | 9250 | -0.053 | -0.3606 | No |
| 75 | STOM | STOM Entrez, Source | stomatin | 9313 | -0.055 | -0.3633 | No |
| 76 | COPS8 | COPS8 Entrez, Source | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 9327 | -0.055 | -0.3624 | No |
| 77 | MARCKS | MARCKS Entrez, Source | myristoylated alanine-rich protein kinase C substrate | 9387 | -0.057 | -0.3649 | No |
| 78 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 9441 | -0.058 | -0.3668 | No |
| 79 | COL12A1 | COL12A1 Entrez, Source | collagen, type XII, alpha 1 | 9641 | -0.064 | -0.3797 | No |
| 80 | MGP | MGP Entrez, Source | matrix Gla protein | 9643 | -0.064 | -0.3775 | No |
| 81 | FN1 | FN1 Entrez, Source | fibronectin 1 | 9917 | -0.072 | -0.3956 | No |
| 82 | CYBRD1 | CYBRD1 Entrez, Source | cytochrome b reductase 1 | 10038 | -0.076 | -0.4021 | No |
| 83 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 10123 | -0.079 | -0.4057 | No |
| 84 | WARS | WARS Entrez, Source | tryptophanyl-tRNA synthetase | 10462 | -0.090 | -0.4281 | No |
| 85 | CBLB | CBLB Entrez, Source | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 10938 | -0.109 | -0.4602 | No |
| 86 | THEX1 | THEX1 Entrez, Source | three prime histone mRNA exonuclease 1 | 11378 | -0.130 | -0.4889 | Yes |
| 87 | SULF2 | SULF2 Entrez, Source | sulfatase 2 | 11417 | -0.132 | -0.4872 | Yes |
| 88 | TCEAL8 | TCEAL8 Entrez, Source | transcription elongation factor A (SII)-like 8 | 11418 | -0.132 | -0.4825 | Yes |
| 89 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 11420 | -0.132 | -0.4780 | Yes |
| 90 | SLC22A17 | SLC22A17 Entrez, Source | solute carrier family 22 (organic cation transporter), member 17 | 11450 | -0.135 | -0.4755 | Yes |
| 91 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 11492 | -0.137 | -0.4738 | Yes |
| 92 | SRPX | SRPX Entrez, Source | sushi-repeat-containing protein, X-linked | 11499 | -0.137 | -0.4694 | Yes |
| 93 | SMTN | SMTN Entrez, Source | smoothelin | 11525 | -0.139 | -0.4664 | Yes |
| 94 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 11630 | -0.145 | -0.4692 | Yes |
| 95 | BMPR2 | BMPR2 Entrez, Source | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 11635 | -0.146 | -0.4644 | Yes |
| 96 | PTGFRN | PTGFRN Entrez, Source | prostaglandin F2 receptor negative regulator | 11678 | -0.148 | -0.4624 | Yes |
| 97 | PAWR | PAWR Entrez, Source | PRKC, apoptosis, WT1, regulator | 11680 | -0.149 | -0.4573 | Yes |
| 98 | NAP1L3 | NAP1L3 Entrez, Source | nucleosome assembly protein 1-like 3 | 11689 | -0.149 | -0.4526 | Yes |
| 99 | BCAM | BCAM Entrez, Source | basal cell adhesion molecule (Lutheran blood group) | 11742 | -0.151 | -0.4513 | Yes |
| 100 | PLSCR4 | PLSCR4 Entrez, Source | phospholipid scramblase 4 | 11764 | -0.153 | -0.4475 | Yes |
| 101 | SIPA1L2 | SIPA1L2 Entrez, Source | signal-induced proliferation-associated 1 like 2 | 11969 | -0.170 | -0.4570 | Yes |
| 102 | VLDLR | VLDLR Entrez, Source | very low density lipoprotein receptor | 12034 | -0.176 | -0.4557 | Yes |
| 103 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12216 | -0.193 | -0.4626 | Yes |
| 104 | KLHL24 | KLHL24 Entrez, Source | kelch-like 24 (Drosophila) | 12386 | -0.213 | -0.4679 | Yes |
| 105 | PLD3 | PLD3 Entrez, Source | phospholipase D family, member 3 | 12403 | -0.215 | -0.4616 | Yes |
| 106 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 12519 | -0.231 | -0.4622 | Yes |
| 107 | TGFBR1 | TGFBR1 Entrez, Source | transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) | 12538 | -0.234 | -0.4553 | Yes |
| 108 | POU3F3 | POU3F3 Entrez, Source | POU domain, class 3, transcription factor 3 | 12587 | -0.242 | -0.4505 | Yes |
| 109 | CASK | CASK Entrez, Source | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 12614 | -0.247 | -0.4438 | Yes |
| 110 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12832 | -0.296 | -0.4499 | Yes |
| 111 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 12840 | -0.300 | -0.4399 | Yes |
| 112 | BACE2 | BACE2 Entrez, Source | beta-site APP-cleaving enzyme 2 | 12874 | -0.311 | -0.4315 | Yes |
| 113 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12902 | -0.323 | -0.4222 | Yes |
| 114 | MAP1B | MAP1B Entrez, Source | microtubule-associated protein 1B | 12944 | -0.337 | -0.4135 | Yes |
| 115 | RAB27A | RAB27A Entrez, Source | RAB27A, member RAS oncogene family | 12981 | -0.351 | -0.4039 | Yes |
| 116 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13010 | -0.371 | -0.3931 | Yes |
| 117 | ZBTB1 | ZBTB1 Entrez, Source | zinc finger and BTB domain containing 1 | 13014 | -0.373 | -0.3802 | Yes |
| 118 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 13047 | -0.395 | -0.3688 | Yes |
| 119 | GULP1 | GULP1 Entrez, Source | GULP, engulfment adaptor PTB domain containing 1 | 13058 | -0.404 | -0.3554 | Yes |
| 120 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 13127 | -0.447 | -0.3449 | Yes |
| 121 | TPBG | TPBG Entrez, Source | trophoblast glycoprotein | 13155 | -0.487 | -0.3299 | Yes |
| 122 | BCAT1 | BCAT1 Entrez, Source | branched chain aminotransferase 1, cytosolic | 13167 | -0.505 | -0.3130 | Yes |
| 123 | RTN1 | RTN1 Entrez, Source | reticulon 1 | 13181 | -0.527 | -0.2955 | Yes |
| 124 | FHL2 | FHL2 Entrez, Source | four and a half LIM domains 2 | 13196 | -0.560 | -0.2770 | Yes |
| 125 | TIMP2 | TIMP2 Entrez, Source | TIMP metallopeptidase inhibitor 2 | 13217 | -0.592 | -0.2578 | Yes |
| 126 | SERINC5 | SERINC5 Entrez, Source | serine incorporator 5 | 13224 | -0.615 | -0.2367 | Yes |
| 127 | DPYSL3 | DPYSL3 Entrez, Source | dihydropyrimidinase-like 3 | 13228 | -0.625 | -0.2150 | Yes |
| 128 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13270 | -0.762 | -0.1914 | Yes |
| 129 | JAG1 | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 13287 | -0.812 | -0.1642 | Yes |
| 130 | KITLG | KITLG Entrez, Source | KIT ligand | 13294 | -0.868 | -0.1342 | Yes |
| 131 | MMP2 | MMP2 Entrez, Source | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 13316 | -1.048 | -0.0990 | Yes |
| 132 | FBLIM1 | FBLIM1 Entrez, Source | filamin binding LIM protein 1 | 13322 | -1.087 | -0.0613 | Yes |
| 133 | CPE | CPE Entrez, Source | carboxypeptidase E | 13342 | -1.792 | 0.0000 | Yes |
