Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | BECKER_TAMOXIFEN_RESISTANT_DN |
| Enrichment Score (ES) | -0.67431253 |
| Normalized Enrichment Score (NES) | -2.0133414 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.007734997 |
| FWER p-Value | 0.094 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 374 | 0.353 | 0.0218 | No |
| 2 | OSBPL1A | OSBPL1A Entrez, Source | oxysterol binding protein-like 1A | 529 | 0.290 | 0.0511 | No |
| 3 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | -0.0036 | No |
| 4 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2222 | 0.114 | -0.0391 | No |
| 5 | MSX1 | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 3040 | 0.084 | -0.0887 | No |
| 6 | ESRRG | ESRRG Entrez, Source | estrogen-related receptor gamma | 3222 | 0.078 | -0.0913 | No |
| 7 | PDZK1 | PDZK1 Entrez, Source | PDZ domain containing 1 | 3333 | 0.075 | -0.0889 | No |
| 8 | COX7A2 | COX7A2 Entrez, Source | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 3647 | 0.068 | -0.1029 | No |
| 9 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 4105 | 0.057 | -0.1292 | No |
| 10 | IRF3 | IRF3 Entrez, Source | interferon regulatory factor 3 | 4799 | 0.042 | -0.1753 | No |
| 11 | RBP1 | RBP1 Entrez, Source | retinol binding protein 1, cellular | 4881 | 0.040 | -0.1757 | No |
| 12 | LBR | LBR Entrez, Source | lamin B receptor | 4976 | 0.038 | -0.1774 | No |
| 13 | CLCA2 | CLCA2 Entrez, Source | chloride channel, calcium activated, family member 2 | 5467 | 0.029 | -0.2102 | No |
| 14 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 6165 | 0.015 | -0.2604 | No |
| 15 | LRP2 | LRP2 Entrez, Source | low density lipoprotein-related protein 2 | 6508 | 0.008 | -0.2850 | No |
| 16 | MSX2 | MSX2 Entrez, Source | msh homeobox homolog 2 (Drosophila) | 7555 | -0.014 | -0.3617 | No |
| 17 | PDCD4 | PDCD4 Entrez, Source | programmed cell death 4 (neoplastic transformation inhibitor) | 8221 | -0.028 | -0.4077 | No |
| 18 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 8679 | -0.039 | -0.4366 | No |
| 19 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 9441 | -0.058 | -0.4856 | No |
| 20 | AGPS | AGPS Entrez, Source | alkylglycerone phosphate synthase | 9442 | -0.058 | -0.4774 | No |
| 21 | NFIB | NFIB Entrez, Source | nuclear factor I/B | 12064 | -0.179 | -0.6491 | Yes |
| 22 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 12100 | -0.181 | -0.6261 | Yes |
| 23 | ORC3L | ORC3L Entrez, Source | origin recognition complex, subunit 3-like (yeast) | 12302 | -0.205 | -0.6122 | Yes |
| 24 | PKIA | PKIA Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 12310 | -0.205 | -0.5837 | Yes |
| 25 | HDAC2 | HDAC2 Entrez, Source | histone deacetylase 2 | 12630 | -0.250 | -0.5724 | Yes |
| 26 | PTPRK | PTPRK Entrez, Source | protein tyrosine phosphatase, receptor type, K | 12652 | -0.254 | -0.5382 | Yes |
| 27 | QKI | QKI Entrez, Source | quaking homolog, KH domain RNA binding (mouse) | 12675 | -0.260 | -0.5032 | Yes |
| 28 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 12692 | -0.262 | -0.4674 | Yes |
| 29 | CEP170 | CEP170 Entrez, Source | centrosomal protein 170kDa | 12737 | -0.273 | -0.4321 | Yes |
| 30 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 12840 | -0.300 | -0.3975 | Yes |
| 31 | KHDRBS3 | KHDRBS3 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 3 | 12904 | -0.323 | -0.3565 | Yes |
| 32 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 13000 | -0.365 | -0.3122 | Yes |
| 33 | TSPAN6 | TSPAN6 Entrez, Source | tetraspanin 6 | 13052 | -0.400 | -0.2595 | Yes |
| 34 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13162 | -0.500 | -0.1971 | Yes |
| 35 | CD24 | CD24 Entrez, Source | CD24 molecule | 13337 | -1.491 | 0.0004 | Yes |
