Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | BILE_ACID_BIOSYNTHESIS |
| Enrichment Score (ES) | 0.6755713 |
| Normalized Enrichment Score (NES) | 1.8224173 |
| Nominal p-value | 0.0020703934 |
| FDR q-value | 0.0112569155 |
| FWER p-Value | 0.819 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 50 | 0.751 | 0.1530 | Yes |
| 2 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 89 | 0.633 | 0.2824 | Yes |
| 3 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 214 | 0.460 | 0.3692 | Yes |
| 4 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 343 | 0.371 | 0.4370 | Yes |
| 5 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 374 | 0.353 | 0.5084 | Yes |
| 6 | CYP27A1 | CYP27A1 Entrez, Source | cytochrome P450, family 27, subfamily A, polypeptide 1 | 578 | 0.274 | 0.5505 | Yes |
| 7 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 580 | 0.273 | 0.6074 | Yes |
| 8 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 656 | 0.251 | 0.6542 | Yes |
| 9 | CYP7A1 | CYP7A1 Entrez, Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 934 | 0.202 | 0.6756 | Yes |
| 10 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 1403 | 0.157 | 0.6732 | No |
| 11 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 1747 | 0.134 | 0.6755 | No |
| 12 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 2402 | 0.107 | 0.6486 | No |
| 13 | CEL | CEL Entrez, Source | carboxyl ester lipase (bile salt-stimulated lipase) | 2678 | 0.096 | 0.6481 | No |
| 14 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 4305 | 0.053 | 0.5370 | No |
| 15 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 5822 | 0.022 | 0.4278 | No |
| 16 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 6279 | 0.012 | 0.3961 | No |
| 17 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 6493 | 0.008 | 0.3818 | No |
| 18 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 6602 | 0.006 | 0.3749 | No |
| 19 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 10696 | -0.098 | 0.0882 | No |
| 20 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 11983 | -0.171 | 0.0275 | No |
| 21 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 12985 | -0.357 | 0.0268 | No |
