Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | BRCA1_MES_UP |
| Enrichment Score (ES) | -0.66024846 |
| Normalized Enrichment Score (NES) | -1.90589 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.020769741 |
| FWER p-Value | 0.439 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FGFBP1 | FGFBP1 Entrez, Source | fibroblast growth factor binding protein 1 | 975 | 0.197 | -0.0413 | No |
| 2 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 2170 | 0.115 | -0.1123 | No |
| 3 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 6165 | 0.015 | -0.4099 | No |
| 4 | TCEA1 | TCEA1 Entrez, Source | transcription elongation factor A (SII), 1 | 6329 | 0.011 | -0.4203 | No |
| 5 | ARF1 | ARF1 Entrez, Source | ADP-ribosylation factor 1 | 7724 | -0.017 | -0.5223 | No |
| 6 | DLG1 | DLG1 Entrez, Source | discs, large homolog 1 (Drosophila) | 8008 | -0.024 | -0.5397 | No |
| 7 | PSMC1 | PSMC1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 8481 | -0.034 | -0.5697 | No |
| 8 | EIF3S8 | EIF3S8 Entrez, Source | eukaryotic translation initiation factor 3, subunit 8, 110kDa | 9060 | -0.048 | -0.6054 | No |
| 9 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 9530 | -0.061 | -0.6309 | No |
| 10 | ACTC1 | ACTC1 Entrez, Source | actin, alpha, cardiac muscle 1 | 9699 | -0.065 | -0.6329 | No |
| 11 | EIF2S1 | EIF2S1 Entrez, Source | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 9999 | -0.075 | -0.6433 | No |
| 12 | LXN | LXN Entrez, Source | latexin | 10057 | -0.076 | -0.6353 | No |
| 13 | ATP6AP1 | ATP6AP1 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 1 | 10068 | -0.077 | -0.6236 | No |
| 14 | DNAJA1 | DNAJA1 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 1 | 10557 | -0.094 | -0.6451 | Yes |
| 15 | CA2 | CA2 Entrez, Source | carbonic anhydrase II | 10674 | -0.098 | -0.6380 | Yes |
| 16 | PSMC2 | PSMC2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 10868 | -0.105 | -0.6354 | Yes |
| 17 | DDX3X | DDX3X Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 11094 | -0.116 | -0.6335 | Yes |
| 18 | PDIA3 | PDIA3 Entrez, Source | protein disulfide isomerase family A, member 3 | 11217 | -0.122 | -0.6229 | Yes |
| 19 | DDX24 | DDX24 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 | 11281 | -0.126 | -0.6073 | Yes |
| 20 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 11404 | -0.131 | -0.5953 | Yes |
| 21 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 11589 | -0.143 | -0.5860 | Yes |
| 22 | NUMB | NUMB Entrez, Source | numb homolog (Drosophila) | 11741 | -0.151 | -0.5728 | Yes |
| 23 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 12156 | -0.187 | -0.5737 | Yes |
| 24 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12216 | -0.193 | -0.5468 | Yes |
| 25 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 12668 | -0.258 | -0.5390 | Yes |
| 26 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 12750 | -0.275 | -0.5005 | Yes |
| 27 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12998 | -0.364 | -0.4602 | Yes |
| 28 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13077 | -0.411 | -0.3996 | Yes |
| 29 | VIM | VIM Entrez, Source | vimentin | 13164 | -0.501 | -0.3249 | Yes |
| 30 | NEFL | NEFL Entrez, Source | neurofilament, light polypeptide 68kDa | 13304 | -0.959 | -0.1802 | Yes |
| 31 | TAGLN | TAGLN Entrez, Source | transgelin | 13326 | -1.131 | 0.0012 | Yes |
