Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | BRCA2_BRCA1_DN |
| Enrichment Score (ES) | 0.5931526 |
| Normalized Enrichment Score (NES) | 1.6966832 |
| Nominal p-value | 0.016949153 |
| FDR q-value | 0.033853788 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 42 | 0.784 | 0.2016 | Yes |
| 2 | PON1 | PON1 Entrez, Source | paraoxonase 1 | 193 | 0.481 | 0.3161 | Yes |
| 3 | ITGAE | ITGAE Entrez, Source | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 252 | 0.432 | 0.4245 | Yes |
| 4 | RGS1 | RGS1 Entrez, Source | regulator of G-protein signalling 1 | 510 | 0.296 | 0.4825 | Yes |
| 5 | FOXO1A | FOXO1A Entrez, Source | forkhead box O1A (rhabdomyosarcoma) | 596 | 0.268 | 0.5462 | Yes |
| 6 | RCL1 | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 904 | 0.206 | 0.5771 | Yes |
| 7 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 1653 | 0.140 | 0.5574 | Yes |
| 8 | WNT2 | WNT2 Entrez, Source | wingless-type MMTV integration site family member 2 | 1662 | 0.139 | 0.5932 | Yes |
| 9 | ZFP161 | ZFP161 Entrez, Source | zinc finger protein 161 homolog (mouse) | 2364 | 0.108 | 0.5688 | No |
| 10 | GFM2 | GFM2 Entrez, Source | G elongation factor, mitochondrial 2 | 3214 | 0.078 | 0.5254 | No |
| 11 | PTPRM | PTPRM Entrez, Source | protein tyrosine phosphatase, receptor type, M | 3619 | 0.068 | 0.5129 | No |
| 12 | PDGFRB | PDGFRB Entrez, Source | platelet-derived growth factor receptor, beta polypeptide | 5158 | 0.035 | 0.4065 | No |
| 13 | GABRP | GABRP Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, pi | 5609 | 0.025 | 0.3793 | No |
| 14 | BRE | BRE Entrez, Source | brain and reproductive organ-expressed (TNFRSF1A modulator) | 6169 | 0.015 | 0.3413 | No |
| 15 | SFRP4 | SFRP4 Entrez, Source | secreted frizzled-related protein 4 | 7164 | -0.006 | 0.2681 | No |
| 16 | IL7 | IL7 Entrez, Source | interleukin 7 | 7643 | -0.015 | 0.2362 | No |
| 17 | KDR | KDR Entrez, Source | kinase insert domain receptor (a type III receptor tyrosine kinase) | 8279 | -0.029 | 0.1962 | No |
| 18 | PTEN | PTEN Entrez, Source | phosphatase and tensin homolog (mutated in multiple advanced cancers 1) | 9345 | -0.056 | 0.1308 | No |
| 19 | MAST1 | MAST1 Entrez, Source | microtubule associated serine/threonine kinase 1 | 9577 | -0.062 | 0.1296 | No |
| 20 | SBNO1 | SBNO1 Entrez, Source | strawberry notch homolog 1 (Drosophila) | 10285 | -0.084 | 0.0985 | No |
| 21 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 10323 | -0.086 | 0.1181 | No |
| 22 | CSNK1E | CSNK1E Entrez, Source | casein kinase 1, epsilon | 10537 | -0.093 | 0.1264 | No |
| 23 | RGL2 | RGL2 Entrez, Source | ral guanine nucleotide dissociation stimulator-like 2 | 10808 | -0.103 | 0.1330 | No |
| 24 | CSRP2 | CSRP2 Entrez, Source | cysteine and glycine-rich protein 2 | 12431 | -0.219 | 0.0684 | No |
