Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | BRENTANI_CELL_CYCLE |
| Enrichment Score (ES) | -0.5694056 |
| Normalized Enrichment Score (NES) | -1.7920448 |
| Nominal p-value | 0.0018450185 |
| FDR q-value | 0.051239032 |
| FWER p-Value | 0.926 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 724 | 0.234 | -0.0226 | No |
| 2 | CDC2L1 | CDC2L1 Entrez, Source | cell division cycle 2-like 1 (PITSLRE proteins) | 1182 | 0.172 | -0.0335 | No |
| 3 | MAX | MAX Entrez, Source | MYC associated factor X | 1464 | 0.152 | -0.0339 | No |
| 4 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 2067 | 0.119 | -0.0629 | No |
| 5 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2307 | 0.110 | -0.0659 | No |
| 6 | CCNF | CCNF Entrez, Source | cyclin F | 3166 | 0.080 | -0.1196 | No |
| 7 | MOS | MOS Entrez, Source | v-mos Moloney murine sarcoma viral oncogene homolog | 3290 | 0.076 | -0.1184 | No |
| 8 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 3805 | 0.064 | -0.1484 | No |
| 9 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 3808 | 0.064 | -0.1398 | No |
| 10 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 4056 | 0.058 | -0.1504 | No |
| 11 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.2007 | No |
| 12 | CDC2L5 | CDC2L5 Entrez, Source | cell division cycle 2-like 5 (cholinesterase-related cell division controller) | 5925 | 0.020 | -0.2825 | No |
| 13 | CCNH | CCNH Entrez, Source | cyclin H | 7280 | -0.008 | -0.3832 | No |
| 14 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 7461 | -0.012 | -0.3952 | No |
| 15 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 7589 | -0.014 | -0.4028 | No |
| 16 | POLR3D | POLR3D Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa | 7669 | -0.016 | -0.4066 | No |
| 17 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 7859 | -0.020 | -0.4181 | No |
| 18 | SKP1A | SKP1A Entrez, Source | S-phase kinase-associated protein 1A (p19A) | 8149 | -0.026 | -0.4362 | No |
| 19 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 8204 | -0.028 | -0.4365 | No |
| 20 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 8707 | -0.039 | -0.4689 | No |
| 21 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 9560 | -0.061 | -0.5246 | No |
| 22 | ZW10 | ZW10 Entrez, Source | ZW10, kinetochore associated, homolog (Drosophila) | 9627 | -0.063 | -0.5209 | No |
| 23 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 9912 | -0.072 | -0.5324 | No |
| 24 | FRK | FRK Entrez, Source | fyn-related kinase | 10336 | -0.086 | -0.5525 | No |
| 25 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 10391 | -0.088 | -0.5446 | No |
| 26 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 10722 | -0.099 | -0.5559 | Yes |
| 27 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 10832 | -0.104 | -0.5498 | Yes |
| 28 | BUB3 | BUB3 Entrez, Source | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) | 10991 | -0.111 | -0.5465 | Yes |
| 29 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 11099 | -0.117 | -0.5387 | Yes |
| 30 | FOSL1 | FOSL1 Entrez, Source | FOS-like antigen 1 | 11180 | -0.120 | -0.5283 | Yes |
| 31 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 11352 | -0.129 | -0.5235 | Yes |
| 32 | CDC16 | CDC16 Entrez, Source | CDC16 cell division cycle 16 homolog (S. cerevisiae) | 11467 | -0.135 | -0.5137 | Yes |
| 33 | CDC27 | CDC27 Entrez, Source | cell division cycle 27 | 11658 | -0.148 | -0.5078 | Yes |
| 34 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11673 | -0.148 | -0.4886 | Yes |
| 35 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11690 | -0.149 | -0.4695 | Yes |
| 36 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 11783 | -0.155 | -0.4552 | Yes |
| 37 | CDK5 | CDK5 Entrez, Source | cyclin-dependent kinase 5 | 12107 | -0.182 | -0.4547 | Yes |
| 38 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.4332 | Yes |
| 39 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 12251 | -0.199 | -0.4126 | Yes |
| 40 | CDC37 | CDC37 Entrez, Source | CDC37 cell division cycle 37 homolog (S. cerevisiae) | 12294 | -0.204 | -0.3879 | Yes |
| 41 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 12531 | -0.233 | -0.3739 | Yes |
| 42 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 12725 | -0.270 | -0.3515 | Yes |
| 43 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12794 | -0.284 | -0.3178 | Yes |
| 44 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12821 | -0.294 | -0.2797 | Yes |
| 45 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 12986 | -0.357 | -0.2433 | Yes |
| 46 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 13016 | -0.374 | -0.1944 | Yes |
| 47 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 13099 | -0.425 | -0.1425 | Yes |
| 48 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13162 | -0.500 | -0.0790 | Yes |
| 49 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13247 | -0.677 | 0.0071 | Yes |
