Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | CALRES_MOUSE_NEOCORTEX_UP |
| Enrichment Score (ES) | -0.5421608 |
| Normalized Enrichment Score (NES) | -1.6396799 |
| Nominal p-value | 0.01002004 |
| FDR q-value | 0.10074544 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 670 | 0.247 | -0.0139 | No |
| 2 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 736 | 0.230 | 0.0153 | No |
| 3 | STK39 | STK39 Entrez, Source | serine threonine kinase 39 (STE20/SPS1 homolog, yeast) | 1121 | 0.180 | 0.0131 | No |
| 4 | AQP4 | AQP4 Entrez, Source | aquaporin 4 | 1360 | 0.160 | 0.0188 | No |
| 5 | SELP | SELP Entrez, Source | selectin P (granule membrane protein 140kDa, antigen CD62) | 1408 | 0.156 | 0.0384 | No |
| 6 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 1938 | 0.125 | 0.0170 | No |
| 7 | GIF | GIF Entrez, Source | gastric intrinsic factor (vitamin B synthesis) | 2300 | 0.110 | 0.0062 | No |
| 8 | SLC6A15 | SLC6A15 Entrez, Source | solute carrier family 6, member 15 | 2693 | 0.096 | -0.0092 | No |
| 9 | CD8B | CD8B Entrez, Source | CD8b molecule | 2848 | 0.090 | -0.0075 | No |
| 10 | PRKD1 | PRKD1 Entrez, Source | protein kinase D1 | 2943 | 0.087 | -0.0017 | No |
| 11 | OPRD1 | OPRD1 Entrez, Source | opioid receptor, delta 1 | 3951 | 0.061 | -0.0684 | No |
| 12 | PRSS15 | PRSS15 Entrez, Source | protease, serine, 15 | 3990 | 0.060 | -0.0625 | No |
| 13 | GPR19 | GPR19 Entrez, Source | G protein-coupled receptor 19 | 4453 | 0.049 | -0.0899 | No |
| 14 | NQO1 | NQO1 Entrez, Source | NAD(P)H dehydrogenase, quinone 1 | 6707 | 0.004 | -0.2587 | No |
| 15 | MTIF2 | MTIF2 Entrez, Source | mitochondrial translational initiation factor 2 | 6712 | 0.004 | -0.2584 | No |
| 16 | CSK | CSK Entrez, Source | c-src tyrosine kinase | 6873 | 0.001 | -0.2703 | No |
| 17 | TUSC4 | TUSC4 Entrez, Source | tumor suppressor candidate 4 | 7068 | -0.003 | -0.2844 | No |
| 18 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 7149 | -0.005 | -0.2896 | No |
| 19 | GAS6 | GAS6 Entrez, Source | growth arrest-specific 6 | 8485 | -0.034 | -0.3849 | No |
| 20 | TUBB6 | TUBB6 Entrez, Source | tubulin, beta 6 | 8711 | -0.039 | -0.3961 | No |
| 21 | POLE3 | POLE3 Entrez, Source | polymerase (DNA directed), epsilon 3 (p17 subunit) | 8809 | -0.041 | -0.3973 | No |
| 22 | GATA4 | GATA4 Entrez, Source | GATA binding protein 4 | 8964 | -0.045 | -0.4022 | No |
| 23 | BMP1 | BMP1 Entrez, Source | bone morphogenetic protein 1 | 9411 | -0.057 | -0.4272 | No |
| 24 | CNOT2 | CNOT2 Entrez, Source | CCR4-NOT transcription complex, subunit 2 | 10411 | -0.089 | -0.4892 | No |
| 25 | SLC12A2 | SLC12A2 Entrez, Source | solute carrier family 12 (sodium/potassium/chloride transporters), member 2 | 11116 | -0.118 | -0.5248 | Yes |
| 26 | EDN2 | EDN2 Entrez, Source | endothelin 2 | 11154 | -0.119 | -0.5099 | Yes |
| 27 | ZBTB7A | ZBTB7A Entrez, Source | zinc finger and BTB domain containing 7A | 11305 | -0.127 | -0.5025 | Yes |
| 28 | BAT3 | BAT3 Entrez, Source | HLA-B associated transcript 3 | 11495 | -0.137 | -0.4964 | Yes |
| 29 | CIT | CIT Entrez, Source | citron (rho-interacting, serine/threonine kinase 21) | 11639 | -0.146 | -0.4856 | Yes |
| 30 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 12013 | -0.174 | -0.4879 | Yes |
| 31 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 12056 | -0.178 | -0.4648 | Yes |
| 32 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 12248 | -0.199 | -0.4498 | Yes |
| 33 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12401 | -0.215 | -0.4295 | Yes |
| 34 | PTPRD | PTPRD Entrez, Source | protein tyrosine phosphatase, receptor type, D | 12478 | -0.224 | -0.4021 | Yes |
| 35 | EIF2AK3 | EIF2AK3 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 3 | 12923 | -0.329 | -0.3868 | Yes |
| 36 | PPIC | PPIC Entrez, Source | peptidylprolyl isomerase C (cyclophilin C) | 13206 | -0.575 | -0.3230 | Yes |
| 37 | TSC22D1 | TSC22D1 Entrez, Source | TSC22 domain family, member 1 | 13246 | -0.674 | -0.2265 | Yes |
| 38 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.581 | 0.0002 | Yes |
